Cetrorelix Acetate CAS 130143-01-0 GnRH Antagonist Peptide Purity (HPLC) ≥98.0% Zoo

Lus piav qhia luv luv:

Lub npe tshuaj: Cetrorelix Acetate

CAS: 130143-01-0 Nr

Cov tsos mob: Dawb hmoov

Peptide Purity (HPLC): ≥98.0%

Synthetic Antagonist ntawm GnRH Receptor

GMP Peptides, API, Siab Zoo

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com 


Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Cetrorelix Acetate (CAS: 130143-01-0) nrog cov khoom zoo.Cetrorelix Acetate yog ib qho gonadotropin-tso hormone (GnRH) antagonist.Ruifu Chemical muab cov khoom ntawm GMP peptides.Ruifu tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav Cetrorelix Acetate,Please contact: alvin@ruifuchem.com

Chemical Properties:

Tshuaj npe Cetrorelix Acetate
Synonyms N-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-4-Chloro-D-Phenylalanyl-3-(3-Pyridinyl)-D-Alanyl-L-Seryl-L-Tyrosyl-N5-(Aminocarbonyl)- D-Ornithyl-L-Leucyl-L-Arginyl-L-Prolyl-D-Alaninamide Diacetate;NS-75A Diacetate;SB-075 Diacetate hmoov
Ib ntus Ac-3-(2-naphthyl)-D-Ala-4-Chloro-D-Phe-3(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala -NH 2
CAS Nr 130143-01-0
Tshuag xwm txheej Nyob rau hauv Tshuag, ntau lawm Scale mus txog Kilograms
Molecular Formula C70H92N17O14
Molecular Luj 1551.16
Cia Temp. Qhov chaw txias & qhuav (-20 ℃).Lub tub yees
Txee lub neej > 2 Xyoo yog khaws cia kom raug
Qeb GMP Peptides
Cov ntaub ntawv COA, MS, HPLC, NMR, MSDS, thiab lwm yam.
Hom Ruifu Tshuaj

Specifications:

Yam khoom Specifications
Qhov tshwm sim Dawb hmoov
Peptide Purity (los ntawm HPLC) ≥98.0% (los ntawm Cheeb Tsam Kev Koom Tes)
Cov ntsiab lus Peptide ≥80.0% (los ntawm %N)
Amino Acid Composition 10% ntawm Theetical
Cov ntsiab lus Acetate ≤10.0% (los ntawm HPLC)
TFA Cov ntsiab lus ≤ 1.0%
Ib leeg Impurity ≤1.0% (los ntawm HPLC)
Cov ntsiab lus dej (Karl Fischer) ≤8.0%
Assay 95.0 ~ 105.0% (los ntawm Anhydrous, acetic acid-dawb)
MS Zoo ib yam
Test Standard Enterprise Standard
Shipping Requirements Ice Bags, Desiccant Bags
Keeb kwm ntawm cov khoom Synthetic
Nco ntsoov Tsuas yog rau Kev Tshawb Fawb, Tsis yog siv rau tib neeg
Kev siv Synthetic Antagonist ntawm GnRH Receptor

Pob & Cia:

Pob:Yas vial (dawb rau peptide packing) los yog iav vial, kom muaj nuj nqis raws li tus neeg siv khoom xav tau.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov txias thiab qhuav (2 ~ 8 ℃) warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.

Qhov zoo:

1

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Daim ntawv thov:

Cetrorelix Acetate (CAS 130143-01-0) yog gonadotropin-tso cov tshuaj hormones (GnRH) antagonist uas tau ua lag luam feem ntau raws li hom npe Cetrotide.Ib tug hluavtaws decapeptide, nws yog siv nyob rau hauv kev pab kev yug me nyuam los inhibit qhov ntxov ntxov luteinizing hormone surges.Cov tshuaj no ua haujlwm los ntawm kev thaiv qhov kev txiav txim ntawm GnRH ntawm lub pituitary, yog li sai sai suppressing cov tshuaj hormones luteinizing (LH) thiab follicle-stimulating hormone (FSH).Cetrorelix Acetate yog tsim los ntawm ntau yam ntawm cov amino acids uas tsis yog-natural amino acids uas tiv thaiv ovulation ntxov nyob rau hauv kev sim tshuaj, ua rau ovulation sau thiab pab reproductive technology kev kho mob rau cov neeg mob nyob rau hauv kev tswj ntawm zes qe menyuam stimulation.
Cetrorelix Acetate yog ib qho tshuaj hormones uas thaiv cov teebmeem ntawm gonadotropin-tso hormone (GnRH).Hauv kev pabcuam kev ua menyuam yaus, hauv cov neeg mob uas tswj cov zes qe menyuam, tiv thaiv ovulation ntxov ntxov.
Pharmacological action Cetrorelix Acetate yog gonadotropin-tso tshuaj hormone (GnRH) antagonist.GnRH tuaj yeem khi rau membrane receptors ntawm pituitary hlwb.Cetrorelix acetate sib tw khi rau cov receptors nrog endogenous GnRH, yog li koob tshuaj tiv thaiv kev tso tawm ntawm luteinizing hormone (LH) thiab follicle stimulating hormone (FSH) los ntawm adenohypophysis.Cov nyhuv inhibitory tau tsim tam sim tom qab kev tswj hwm ntawm cetrorelix acetate, thiab cov nyhuv inhibitory tuaj yeem tswj tau los ntawm kev kho mob tas li.Rau cov poj niam, Cetrorelix Acetate tuaj yeem ncua sijhawm LH ncov, yog li ncua sijhawm ovulation.Rau cov poj niam uas tau txais kev txhawb nqa ntawm zes qe menyuam, lub sijhawm ua haujlwm yog nyob ntawm koob tshuaj.Ib koob tshuaj cetrorelix 3mg tau kwv yees tias muaj cov nyhuv inhibitory tsawg kawg yog 4 hnub, nrog rau cov nyhuv inhibitory ntawm kwv yees li 70% Hnub 4. Kev rov ua haujlwm ntawm cetrorelix acetate 0.25mg txhua 24 teev tuaj yeem tswj tau nws cov nyhuv.Cov tshuaj hormone-antagonizing nyhuv ntawm Cetrorelix Acetate tau thim rov qab tag nrho thaum kawg ntawm kev kho mob hauv cov tsiaj thiab tib neeg.
Cetrorelix Acetate yog lub zog antagonist ntawm GnRH receptor nrog IC50 tus nqi ntawm 1.21 nM.
Lub hom phiaj IC50: 1.21 nM GnRH.

Sau koj cov lus ntawm no thiab xa tuaj rau peb