Cisatracurium Besylate CAS 96946-42-8 Assay 95.0% ~ 102.0% API Hoobkas Zoo
Chaw tsim tshuaj paus nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Cisatracurium Besylate
CAS: 96946-42-8 Nr
API High Quality, Commercial Production
Tshuaj npe | Cisatracurium Besylate |
CAS Nr | 96946-42-8 |
CAT Number | RF-API 13 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C53H72N2O12.2C6H5O3S |
Molecular Luj | 1243.49 Nws |
Melting Point | 90.0 ~ 93.0 ℃ |
Shipping Condition | Nyob rau hauv Ambient Kub |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov, tsis muaj ntxhiab, me ntsis hygroscopic |
Solubility | Dawb soluble hauv dichloromethane, acetonitrile, me ntsis soluble hauv dej |
Kev sib hloov tshwj xeeb | -35.0 ° rau -45.0 ° (C = 10mg / ml, 0.1mg / ml benzene sulfonic acid) |
Kev txheeb xyuas | Dissolve nrog dilute hydrochoric acid, dropwise dilute bismuth potassium iodide TS, daj nag lossis daus yuav raug tsim |
Kev txheeb xyuas | 1. HPLC;2. IR |
Assay | 95.0 ~ 102.0% (C65H82N2O18S2 ntawm lub hauv paus qhuav) |
pH | 3.5 rau 5.0 |
Clarity & Xim ntawm cov tshuaj | Yuav tsum Clear & Colorless |
Poob rau ziab | ≤ 2.0% |
Residual ntawm Ignition | ≤ 0.20% |
Hnyav Hlau | ≤ 20ppm |
Trans-Trans Isomer | ≤0.50% |
Cis-Trans Isomer | ≤0.50% |
Mono-quaternaries | ≤ 1.50% |
Lwm tus neeg Impurity | ≤ 1.50% |
Tag nrho cov impurities | ≤ 5.0% |
Optical Isomer SS-Isomer Cov | ≤ 1.50% |
Optical Isomer RS- Isomer Cov | ≤ 1.00% |
Sulfate | ≤ 50ppm |
Ethyl | ≤0.50% |
Acetone | ≤0.50% |
Methanol | ≤ 0.3% |
Dichloromethane | ≤0.06% |
Cov tshuaj acetonitrile | ≤ 0.041% |
Methylbenzene | ≤ 0.089% |
Residual Solvents Acetonitrile | ≤410ppm |
Test Standard | Suav Pharmacopoeia (CP) |
Kev siv | Active Pharmaceutical Ingredients (API) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Cisatracurium Besylate (CAS 96946-42-8) yog benzene sulfonate ntsev daim ntawv ntawm atracurium.Nws yog ib yam ntawm cov hluavtaws hluavtaws uas tsis yog-depolarizing cov leeg nqaij so nrog nws lub luag haujlwm zoo ib yam li tubocurarine.Cov koob tshuaj kho mob tsis cuam tshuam rau lub plawv, lub siab thiab lub raum ua haujlwm.Nws kuj tsis muaj khoom tsub zuj zuj.Nws kuj tuaj yeem ua rau muaj kev tso tawm ntawm histamine thaum siv ntau npaum li cas.Rau cov leeg nqaij so lossis kev tswj ua pa yuav tsum tau ua hauv kev phais, piv nrog tam sim no cov chaw kho mob loj cov leeg-txo cov tshuaj loog, cisatracurium besylate tsis metabolized los ntawm daim siab lossis lub raum, thiab muaj cov hlab plawv;nws cov nyhuv ntawm cov leeg so yog 3 npaug zog li atracurium yam tsis muaj kev mob plawv.Cisatracurium besylate feem ntau yog siv rau kev siv tshuaj loog, thiab tuaj yeem siv dav hauv intubation, kho lub siab thiab lub raum tsis ua haujlwm, siv rau hauv kev phais plawv thiab cov neeg laus thiab menyuam yaus.Piv nrog rau atracurium, cov khoom no tsis muaj kev cuam tshuam ntawm cov tshuaj histamine tso tawm;Txawm li cas los xij, qhov tsis zoo yog tias cov neeg mob lub siab thiab lub raum tsis ua haujlwm yuav tsum tau ceev faj.Txij li thaum xyoo 1996 thawj zaug thaum cov tshuaj no tau nkag mus rau hauv kev ua lag luam hauv UK, cov teb chaws txawv teb chaws tau maj mam siv nws los hloov vecuronium thiab atracurium ua lub ntsiab ntawm kev kho cov leeg nqaij.