Cyano-Irbesartan CAS 138401-24-8 Purity > 98.0% (HPLC) Irbesartan Intermediate Factory
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
CAS Nr .: 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Tshuaj npe | Cyano-Irbesartan |
Synonyms | CyanoIrbesartan;Irbesartan Cyano impurity;Irbesartan Hydrocarbon;Irbesartan Impurity 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-ib;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile |
CAS Nr | 138401-24-8 |
CAT Number | Qauv: RF-PI1892 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C25H27N3O |
Molecular Luj | 385.51 ib |
Qhov ntom | 1.15 |
Solubility (Soluble hauv) | Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Yuav luag Dawb Hmoov rau Crystal |
Purity / Analysis Method | > 98.0% (HPLC) |
Purity | > 97.0% (Nrog Tag Nrho Nitrogen) |
Melting Point | 91.0 txog 95.0 ℃ |
Poob rau ziab | <1.00% |
Ib leeg Impurity | <1.00% |
Hnyav Hlau | <20 ppm |
Infrared Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate / Impurity ntawm Irbesartan (CAS: 138402-11-6) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Cyano-Irbesartan (CAS: 138401-24-8) yog ib qho nruab nrab lossis impurity ntawm Irbesartan (CAS: 138402-11-6).Irbesartan yog angiotensin II (Angiotensin II, Ang II) receptor inhibitor.Angiotensin II receptors muab faib ua ob hom: AT1 thiab AT2.Irbesartan xaiv blocks AT1 receptor ntawm AnglI.Nws tuaj yeem cuam tshuam kev hloov pauv ntawm Ang rau hauv Ang, tuaj yeem tiv thaiv cov angiotensin-hloov enzyme 1 receptor (AT1).Cov nyhuv antagonistic ntawm AT1 yog 8500 npaug ntawm AT2.Nws tuaj yeem xaiv qhov kev khi ntawm Ang thiab AT1 receptor los ntawm Inhibit vasoconstriction thiab tso tawm ntawm aldosterone, uas ua rau muaj cov nyhuv hypotensive.Cov khoom no tsis inhibit angiotensin converting enzyme (ACE), renin, lwm yam tshuaj hormones receptors, thiab nws tsis inhibit ion channels ntsig txog ntshav siab thiab sodium tshuav nyiaj li cas.Irbesartan kuj tseem tuaj yeem txo cov hluav taws xob hloov kho ntawm myocardium, yog li txo qis kev tuag ntawm cov neeg mob ntshav siab.Tam sim no nws yog cov tshuaj zoo tshaj plaws rau kev kho mob ntshav siab thiab kab mob plawv.