Hydroxypropyl-β-Cyclodextrin CAS 128446-35-5 (HP-β-CD) Pharmaceutical Excipients

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Lub npe tshuaj: Hydroxypropyl-β-Cyclodextrin

Synonyms: Cyclodextrin HPB;HPBCD;HP-β-CD

CAS: 128446-35-5 Nr

Dawb los yog Yuav luag Dawb Amorphous lossis Crystalline Hmoov

Hu rau: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

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Nqe lus piav qhia:

Ruifu Chemical yog cov chaw tsim khoom ntawm Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Hydroxypropyl-β-Cyclodextrin,Please contact: alvin@ruifuchem.com

Chemical Properties:

Tshuaj npe	Hydroxypropyl-β-Cyclodextrin
Synonyms	Cyclodextrin HPB;Hydroxypropyl-Beta-Cyclodextrin;(2-Hydroxypropyl)-β-Cyclodextrin;(2-Hydroxypropyl)-beta-Cyclodextrin;beta-Hydroxypropylcyclodextrin;HBC;HPBCD;HP-β-CD
Tshuag xwm txheej	Hauv Tshuag, Kev Lag Luam Ntau Lawm
CAS Nr	128446-35-5
Molecular Formula	C63H112O42
Molecular Luj	1541.54 g / mol
Melting Point	262.0 ~ 269.0 ℃
Qhov ntom	1.05 Nws
Kev sib hloov tshwj xeeb [a]20/D	+120 ° txog +135 ° C = 1, H2O
Dej Solubility	Soluble hauv dej
COA & MSDS	Muaj
Qauv dawb	Muaj
Keeb kwm	Shanghai, Suav
Hom	Ruifu Tshuaj

Specifications:

Cov khoom	Specifications	Cov txiaj ntsig
Qhov tshwm sim	Dawb hmoov, Insipid, Innocent	Ua raws
IR Spectrum	Tib Qhov Sib Nqus Bands nrog USP Hydroxypropyl Betadex RS	Ua raws
pH	5.0 ~ 7.5 hli	6.57 ib
Clarity of Solution	Clear thiab Colorless Solution	Ua raws
Poob rau ziab	≤ 10.0%	3.5%
Residue ntawm Ignition	≤ 0.20%	0.09%
Hnyav Hlau	≤ 20ppm	<10ppm
Chloride	≤ 0.05%	<0.05%
Molar Hloov	0.4 ~ 1.5 hli	0.63 ib
Kev coj ua	10% (w/v) Dej daws ≤200μS/cm	154 µS/cm
Degree ntawm Hloov	2.8-10.5 Nws	5.3
Residue Betadex	≤ 1.50%	0.12%
Propylene Glycol	≤ 2.50%	0.29%
Propylene Oxide	≤1ppm	<1 ppm
Lwm Yam Ib Leeg Impurity	≤ 0.25%	<0.25%
Lwm yam impurities	≤1.00% (Tsis suav nrog Betadex thiab Propylen Glycol)	0.51%
TAMC	≤1000cfu / g	30 cfu/g
TYMC	≤100cfu / g	10 cfu/g
Escherichia Coli	Tsis Detectable	Ua raws
Salmonella	Tsis muaj	Tsis muaj
Cov kab mob endotoxins	<10IU/g	<10IU/g
Xaus	Kuaj thiab ua raws li tus qauv USP35

Pob / Cia /Shipping:

Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia txias:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav thiab zoo-ventilated warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.Incompatible nrog muaj zog oxidizing neeg sawv cev.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.

Qhov zoo:

Muaj peev xwm txaus: Muaj cov chaw txaus thiab cov kws tshaj lij

Kev Pabcuam Kev Ua Haujlwm: Ib qho kev pabcuam kev yuav khoom

Pob OEM: Kev cai pob thiab daim ntawv lo muaj

Kev xa khoom sai: Yog tias nyob hauv Tshuag, peb hnub xa khoom lav

Stable Supply: Khaws cov khoom tsim nyog

Kev them nyiaj yug Technical: Technology tov muaj

Kev Pabcuam Synthesis: Ntau yam ntawm grams mus rau kilos

High Quality: Tsim kom muaj kev ruaj ntseg zoo

FAQ:

Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.

Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.

Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.

ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.

Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.

Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.

MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.

Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.

Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.

Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.

Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.

Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.

128446-35-5 - Kev pheej hmoo thiab kev nyab xeeb:

Kev nyab xeeb piav qhia	24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag.
WGK Germany	3
RTECS	GU2293332
HS Code	3505100 000

128446-35-5 - Siv:

Hydroxypropyl-β-Cyclodextrin (HPBCD; HP-β-CD) (CAS: 128446-35-5) yog siv dav siv hloov kho cyclodextrin, lipophilic kab noj hniav tsim los ntawm 7 cov piam thaj.Cov tshuaj solubility hauv dej yog txhim kho zoo heev los ntawm kev sib xyaw nrog HP-β-CD.Enteric txheej, sustained tso formulations, buccal thiab transdermal tshuaj xa.
Hydroxypropyl-β-Cyclodextrin, hydroxyalkyl derivative, pom daim ntawv thov raws li lub tsheb formulation uas yog siv los txhim kho cov solubility ntawm cov tshuaj nyob rau hauv aqueous daws rau kev ua tau zoo ntawm kev xa cov tshuaj kho mob rau cov kab mob lom.Nws yog feem ntau ua hauj lwm los hloov α-, β- thiab γ-Cyclodextrins.

128446-35-5 - Pharmaceutical Applications:

Hydroxypropyl betadex tau raug tshawb xyuas dav hauv cov chaw muag tshuaj thiab tau siv los ua cov tshuaj solubilizer rau hydrophobic molecules hauv cov kua hauv qhov ncauj, cov kua hauv qhov ncauj, parenterals, cov tshuaj txhaj tshuaj siab, cov tshuaj inhalers qhuav, thiab cov tshuaj pleev ib ce.Nws kuj tau pom tias ua tus stabilizer thaum ua thiab khaws cia ntawm cov formulations.Hydroxypropyl betadex suav nrog cov complexes tau tshaj tawm los qhia cov khoom siv kho tshuab sib txawv ntawm cov ntaub ntawv ntshiab.Qhov kev tshaj tawm zoo ntawm hydroxypropyl betadex tshaj qhov tsis hloov pauv b-cyclodextrin yog nws cov dej ntau dua solubility.

128446-35-5 - Ua haujlwm:

1. Solubilization thiab solubilization, ua rau cov tshuaj insoluble yaj, txhim kho cov solubility ntawm active Cheebtsam ntawm oily tshuaj, lub hom phiaj kev xa tshuaj thiab tiv thaiv kev ua tau zoo ntawm cov khoom xyaw tshuaj.
2. Txhim kho bioavailability ntawm cov tshuaj, ua kom cov nyhuv curative ntawm cov tshuaj los yog txo qhov ntau npaum.
3. Kho lossis tswj qhov tso tawm ntawm cov tshuaj kom txo tau cov kev mob tshwm sim.
4. Npog tus ntxhiab tsw phem.

128446-35-5 - Xov.Daim ntawv thov:

1) Hauv kev lag luam tshuaj,
1. Hydroxypropyl Beta Cyclodextrin tuaj yeem ua rau kom cov tshuaj solubility ntawm cov tshuaj thiab cov khoom muaj roj ntsha, kuj ntxiv cov nyhuv zoo thiab txo cov koob tshuaj.
2. HP-β-CD tuaj yeem tswj lossis kho qhov nrawm nrawm, txo cov tshuaj toxicity thiab txhim khu kev ruaj ntseg ntawm cov tshuaj.
3. Ib qho zoo tagnrho txhaj tshuaj solubilizer thiab cov tshuaj excipients vim yog qhov qis qis thiab kev ua haujlwm hemolytic, tsis muaj nqaij tawv.
4. HP-β-CD tsis yog tsuas yog siv rau hauv cov tshuaj hauv qhov ncauj, txhaj tshuaj, mucosal tshuaj xa system, transdermal tshuaj xa system, lipotropy tsom cov neeg nqa tshuaj, tab sis kuj tuaj yeem siv los ua cov tshuaj tiv thaiv kab mob thiab stabilizer.
5. Txhawm rau txhim kho organoleptic zog ntawm iab los yog tsis kaj siab active.
2) Hauv cov khoom noj khoom haus,
1. HP-β-CD tuaj yeem tiv thaiv evaporation ntawm volatile tshuaj tswj kev ruaj ntseg ntawm nws cov as-ham, tshem tawm cov ntxhiab tsw phem thiab tuaj yeem txhim kho cov teebmeem ntawm emulsification nrog kev sib xyaw ua ke ntawm cov khoom noj emulsifiers.
2. HP-β-CD kuj tseem tuaj yeem ua rau cov khoom noj khoom haus tso tawm maj mam, tsa cov nyhuv los tiv thaiv corrosion thiab ua rau lub neej txee ntawm cov zaub mov.
3) Hauv kev lag luam tshuaj pleev ib ce
1. Nyob rau hauv cov tshuaj pleev ib ce raw khoom siv stabilizer, emulsifier, solubilizer thiab lwm yam.
2. HP-β-CD tuaj yeem txo qhov stimulation ntawm daim tawv nqaij, thiab txhim khu kev ruaj ntseg ntawm cov khoom siv tau zoo
3. HP-β-CD tuaj yeem txo lossis npog qhov tsw phem ntawm cov khoom noj khoom haus molecular.
4. Tiv thaiv cov khoom muaj pes tsawg leeg ntawm volatile, oxidation, ua rau kom infusibility, essence, naj hoom dej-soluble thiab Khaws cov tshuaj tsw qab qeeb thiab kav ntev.