D-Sorbitol CAS 50-70-4 Assay 97.0 ~ 100.5% Hoobkas Zoo
Shanghai Ruifu Chemical Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm D-Sorbitol (CAS: 50-70-4) hauv Suav teb nrog cov khoom zoo, muaj peev xwm ntau lawm 20000 tons hauv ib xyoos.Peb D-Sorbitol tau muag zoo nyob rau hauv kev lag luam hauv tsev thiab txawv teb chaws, muaj kev ntseeg siab los ntawm cov neeg siv khoom.Peb tuaj yeem muab kev xa khoom thoob ntiaj teb, me me thiab ntau qhov ntau.Yog tias koj xav yuav D-Sorbitol,Please contact: alvin@ruifuchem.com
Tshuaj npe | D-Sorbitol |
Synonyms | D-(-)-Sorbitol;Sorbitol;(-) -Sorbitol;Dextro-Sorbitol;D-Glucitol;D-Sorbol;Gulitol;Esasorb;L-Gulitol |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 20000 Tons ib xyoos |
CAS Nr | 50-70-4 ib |
Molecular Formula | C6H14O6 |
Molecular Luj | 182.17 Nws |
Melting Point | 98.0 ~ 100.0 ℃ (lit.) |
Qhov ntom | 1.28 g / ml ntawm 25 ℃ |
Refractive Index n20/D | 1.46 ib |
rhiab heev | Hygroscopic |
Dej Solubility | Soluble heev hauv dej, Yuav luag Transparency |
Solubility | Insoluble hauv Ethanol (96 feem pua), Insoluble hauv Ether |
Cia Temp. | Muab ntim rau hauv Qhuav, Khaws ntawm Chav Kub |
COA & MSDS | Muaj |
Hom | Ruifu Tshuaj |
Hazard Codes | Xis | RTECS | LZ4290000 |
Risk Statements | 36/37/38 ib | F | 3 |
Cov lus hais txog kev nyab xeeb | 8-36-26-24/25 ib | TSCA | Yog lawm |
WGK Germany | 2 | HS Code | 2905440000 ib |
Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
Qhov tshwm sim | Dawb Crystalline hmoov | Ua raws |
Saj | Qab zib saj, hnov txias | Ua raws |
Kev daws teeb meem | Ntshiab thiab tsis muaj xim (5.0g hauv 20ml ntawm H2O) | Ua raws |
Chloride (Cl) | ≤ 0.005% | <0.005% |
Sulfate (SO4) | ≤ 0.005% | <0.005% |
Heavy Metals (raws li Pb) | ≤ 5.0ppm | <5.0ppm |
Nickel (Ni) | ≤ 1.0ppm | <1.0ppm |
Lead (Pb) | ≤ 1.0ppm | <1.0ppm |
Arsenic (As2O3) | ≤ 1.0ppm | <1.0ppm |
Txo Qab Zib (raws li Glucose) | ≤ 0.30% | <0.10% |
Tag Nrho Qab Zib | ≤0.50% | <0.50% |
Dej | ≤ 1.50% | <1.50% |
Residue ntawm Ignition (Sulfated) | ≤0.10% | <0.10% |
D-Sorbitol Assay | 97.0 ~ 102.0% (ntawm qhuav hauv paus) | 99.2% |
Tus nqi pH | 3.5 txog 7.0 (50% aq. Solution) | 6.0 |
Total Aerobic suav | ≤1000 cfu / g | <1000 cfu/g |
Tag nrho cov pwm thiab cov poov xab | ≤ 100 cfu / g | <100 cfu/g |
Escherichia Coli | Tsis muaj | Tsis muaj |
Salmonella | Tsis muaj | Tsis muaj |
Cov kab mob endotoxins | Ua raws | Ua raws |
Infrared Spectrum | Raws li tus qauv | Ua raws |
Xaus | Cov khoom no los ntawm Kev Tshawb Fawb Accords nrog cov Specifications |
D-Sorbitol (CAS: 50-70-4) EP8.7 Test Method
D-Glucitol (D-sorbitol).
Cov ntsiab lus: 97.0 feem pua rau 102.0 feem pua (cov khoom tsis muaj dej).
CEEB TOOM
Cov tsos mob: dawb los yog yuav luag dawb, crystalline hmoov.
Solubility: soluble hauv dej heev, xyaum insoluble hauv ethanol (96 feem pua).
Nws qhia txog polymorphism (5.9).
KEV KHO MOB
Kev txheeb xyuas thawj zaug: A.
Kev qhia thib ob: B, C, D
A. Tshawb xyuas cov chromatograms uas tau txais hauv qhov kev xeem.
Cov txiaj ntsig: lub ntsiab lus tseem ceeb hauv chromatogram tau txais nrog cov tshuaj ntsuam xyuas zoo sib xws hauv lub sijhawm khaws cia thiab qhov loj me rau lub ntsiab lus tseem ceeb hauv chromatogram tau nrog kev siv tshuaj (a).
B. Dissolve 0.5 g nrog cua sov nyob rau hauv ib tug sib tov ntawm 0.5 mL ntawm pyridine Rand 5 mL ntawm acetic anhydride R. Tom qab 10 min ncuav lub tov rau hauv 25 mL ntawm dej Rand cia sawv ntsug nyob rau hauv dej txias rau 2 h.Lub precipitate, recrystallised los ntawm ib tug me me ntim ntawm ethanol (96 ib xees) R thiab qhuav nyob rau hauv vacuo, melts (2.2.14) ntawm 98 ℃ to 104 ℃.
C. Nyias-txheej chromatography (2.2.27).
Test daws.Dissolve 25 mg ntawm cov tshuaj yuav tsum tau soj ntsuam nyob rau hauv dej R thiab dilute mus rau 10 mL nrog tib hnyav.
Kev daws teeb meem (a).Dissolve 25 mg ntawm sorbitol CRS hauv dej R thiab dilute mus rau 10 mL nrog tib cov kuab tshuaj.
Kev daws teeb meem (b).Dissolve 25 mg ntawm mannitol CRS thiab 25 mg ntawm sorbitol CRS hauv dej R thiab dilute mus rau 10 mL nrog tib cov kuab tshuaj.
Phaj: TLC silica gel G phaj R.
Mobile theem: dej R, ethyl acetate R, propanol R (10: 20: 70V / V / V).
Daim ntawv thov: 2 μL
Kev loj hlob: tshaj ib txoj kev ntawm 17cm
Qhuav: hauv huab cua.
Kev kuaj pom: tshuaj tsuag nrog 4-aminobenzoic acid tov R;qhuav nyob rau hauv ib tug tam sim no ntawm huab cua txias kom txog thaum lub acetone tshem tawm;kub ntawm 100 ℃ rau 15 min;cia txias thiab tshuaj tsuag nrog 2g / L tov ntawm sodium periodate R;qhuav nyob rau hauv ib tug tam sim no ntawm huab cua txias;Kub ntawm 100 ℃ rau 15 min.
System suitability: reference solution (b):
- cov chromatogram qhia 2 qhov sib cais kom meej.
Cov txiaj ntsig: qhov chaw tseem ceeb hauv chromatogram tau txais nrog cov tshuaj ntsuam xyuas zoo sib xws hauv txoj hauj lwm, xim thiab qhov loj me rau qhov chaw tseem ceeb hauv chromatogram tau nrog kev siv tshuaj (a).
D. Kev sib hloov kho qhov muag tshwj xeeb (2.2.7): +4.0 txog +7.0 (anhydrou tshuaj).
Dissolve 5.00 g ntawm cov tshuaj yuav tsum tau soj ntsuam thiab 6.4 g ntawm disodium tetraborate R nyob rau hauv 40 mL dej R. Cia sawv ntsug rau 1h, co qee zaus, thiab dilute mus rau 50.0mL nrog dej R. Lim yog tsim nyog.
KEV KAWM
Qhov tshwm sim ntawm kev daws.Qhov kev daws teeb meem yog qhov tseeb (2.2.1) thiab tsis muaj xim (2.2.2, Txoj Kev II).
Dissolve 5 g hauv dej R thiab dilute mus rau 50 mL nrog tib cov kuab tshuaj.
Conductivity (2.2.38): siab tshaj 20 μS·cm−1
Dissolve 20.0 g incarbon dioxide-dawb dej R npaj los ntawm distilled dej R thiab dilute mus rau 100.0 mL nrog tib hnyav.Ntsuas cov conductivity ntawm cov tshuaj thaum maj mam nplawm nrog ib tug sib nqus stirrer.
Txo cov suab thaj: siab tshaj 0.2 feem pua, qhia tias yog cov piam thaj sib npaug.
Dissolve 5.0 g hauv 6 mL dej R nrog kev pab ntawm maj mam tshav kub.Txias thiab ntxiv 20 mL ntawm cupri-citric tov R thiab ob peb iav hlaws dai.Tshav kub kom npau npau pib tom qab 4 feeb thiab tuav lub boil rau 3 feeb.Txias sai sai thiab ntxiv 100 mL ntawm 2.4 feem pua V / V tov ntawm glacial acetic acid R thiab 20.0 mL ntawm 0.025 M iodine.Nrog tas li co, ntxiv 25 mL ntawm ib tug sib tov ntawm 6 ntim ntawm hydrochloric acid R thiab 94 ntim dej R thiab, thaum lub precipitate tau yaj, titrate tshaj ntawm iodine nrog 0.05 M sodium thiosulfate siv 1 mL ntawm starch tov R, ntxiv. mus rau qhov kawg ntawm titration, raws li qhov taw qhia.Yuav tsum tsis pub tsawg tshaj 12.8 mL ntawm 0.05 M sodium thiosulfate.
Cov khoom muaj feem xyuam.Ua kua chromatography (2.2.29).
Test daws.Dissolve 5.0 g ntawm cov tshuaj yuav tsum tau kuaj nyob rau hauv 20 mL dej R thiab dilute mus rau 100.0 mL nrog tib hnyav.
Kev daws teeb meem (a).Dissolve 0.50g ntawm sorbitol CRS hauv 2 mL dej R thiab dilute mus rau 10.0 mL nrog tib cov kuab tshuaj.
Kev daws teeb meem (b).Dilute 2.0mL ntawm cov tshuaj ntsuam xyuas rau 100.0 mL nrog dej R.
Kev daws teeb meem (c).Dilute 5.0 mL ntawm kev siv tshuaj (b) rau 100.0 mL nrog dej R.
Kev daws teeb meem (d).Dissolve 0.5g ntawm sorbitol R thiab 0.5 g ntawm mannitol R ( impurity A) hauv 5 mL dej R thiab dilute mus rau 10.0 mL nrog tib cov kuab tshuaj.
Kem:
Luas = 0.3 m, Ø 7.8 mm
-stationary theem: muaj zog cation-exchange resin (calcium form) R (9 μm);
Qhov kub thiab txias: 85 ± 1 ° C
Mobile theem: degassed dej R.
Tus nqi ntws: 0.5mL / min
Kev kuaj pom: refractometer khaws cia ntawm qhov kub thiab txias (piv txwv li 35 ° C).
Txhaj tshuaj: 20μL ntawm cov tshuaj ntsuam xyuas thiab siv cov kev daws teeb meem (b) (c) thiab (d)
Lub sijhawm ua haujlwm: ob zaug lub sijhawm khaws cia ntawm sorbitol.
Cov txheeb ze tuav nrog siv sorbitol (lub sijhawm khaws cia = txog 27 min): impurity C = txog 0.6;impurity A = txog 0.8;impurity B = txog 1.1.
System suitability: reference solution (d):
-kev daws teeb meem: yam tsawg kawg 2.0 nruab nrab ntawm lub ncov vim impurity A thiab sorbitol.
txwv:
-Txhua yam impurity: rau txhua qhov impurity, tsis pub ntau tshaj qhov chaw ntawm lub hauv paus ncov hauv chromatogram tau nrog kev siv tshuaj (b) (2 feem pua);
-tag nrho: tsis pub ntau tshaj 1.5 npaug ntawm thaj tsam ntawm lub hauv paus ncov hauv chromatogram tau nrog kev siv tshuaj (b) (3 feem pua);
-tsis quav ntsej txwv: thaj tsam ntawm lub hauv paus ncov hauv chromatogram tau txais nrog kev siv tshuaj (c) (0.1 feem pua).
Lead (2.4.10): siab tshaj 0.5ppm.
Nickel (2.4.15): siab tshaj 1 ppm.
Dissolve cov tshuaj yuav tsum tau kuaj nyob rau hauv 150.0 mL ntawm cov tshuaj sib tov ntawm cov kuab tshuaj.
Dej (2.5.12): siab tshaj 1.5 feem pua, txiav txim siab ntawm 1.00 g.Siv ib qho sib xyaw ntawm 1 ntim ntawm formamide R thiab 2 ntim ntawm anhydrous methanol R ua hnyav.
Cov kab mob microbial
Yog hais tias npaj rau siv nyob rau hauv kev tsim cov parenteral npaj:
- TAMC: kev lees paub 102CFU/g (2.6.12).
Yog tias tsis npaj rau kev siv hauv kev tsim cov tshuaj parenteral:
- TAMC: kev lees paub 103CFU/g (2.6.12);
- TYMC: kev lees paub 102CFU/g (2.6.12);
- tsis muaj Escherichia coli (2.6.13);
- tsis muaj Salmonella (2.6.13).
Cov kab mob endotoxins (2.6.14).Yog tias npaj rau kev siv hauv kev tsim cov tshuaj parenteral yam tsis muaj cov txheej txheem ntxiv tsim nyog rau kev tshem tawm cov kab mob endotoxins:
- tsawg dua 4 IU / g rau kev npaj parenteral uas muaj cov ntsiab lus tsawg dua 100g / L ntawm sorbitol
- tsawg dua 2.5 IU / g rau kev npaj parenteral uas muaj cov ntsiab lus ntawm 100g / L lossis ntau dua ntawm sorbitol
QHIA
Liquid chromatography (2.2.29) raws li tau piav qhia hauv kev sim rau cov tshuaj muaj feem xyuam nrog kev hloov kho hauv qab no.
Txhaj tshuaj: kuaj tshuaj thiab siv tshuaj (a).
Xam cov ntsiab lus feem pua ntawm D-sorbitol los ntawm cov ntsiab lus tshaj tawm ntawm sorbitol CRS.
LABELING
Daim ntawv lo hais tias:
- qhov twg siv tau, qhov siab tshaj plaws ntawm cov kab mob endotoxins;
- qhov muaj feem xyuam, cov khoom tsim nyog rau kev siv cov khoom siv parenteral npaj.
IMPURITIES
A. D-mannitol,
B. D-iditol,
C. 4-O-α-D-glucopyranosyl-D-glucitol (D-maltitol).
D-Sorbitol (CAS: 50-70-4) USP Test Method
DEFINITION
Sorbitol muaj NLT 91.0% thiab NMT 100.5% ntawm D-sorbitol, suav nrog lub hauv paus anhydrous.Tus nqi ntawm tag nrho cov suab thaj, lwm yam dej cawv polyhydric, thiab ib qho hexitol anhydrides, yog tias kuaj pom, tsis suav nrog hauv cov kev xav tau, lossis nyob rau hauv tus lej suav raws li Lwm Cov Khoom Siv Hauv Cov Ntawv Ceeb Toom.
IDENTIFICATION
• A.
Piv txwv li: 1g ntawm Sorbitol hauv 75 mL dej
Kev tsom xam: Hloov 3 mL ntawm cov qauv tshuaj mus rau lub raj 15-cm, thiab ntxiv 3 mL ntawm cov tshuaj catechol tshiab (1 hauv 10), thiab sib tov.Ntxiv 6 mL ntawm sulfuric acid, maj mam muab tso rau hauv lub qhov cub rau 30 feeb.
• B. Lub sij hawm tuav ntawm lub ncov loj ntawm cov qauv kev daws teeb meem sib raug rau qhov ntawd los ntawm cov txheej txheem kev daws teeb meem, raws li tau txais hauv Assay.
QHIA
• KEV PAB CUAM
Mobile theem: Siv dej degassed.
Kev daws teeb meem tsim nyog: Npaj cov tshuaj uas muaj 4.8 mg / g ntawm txhua USP Sorbitol RS thiab mannitol
Kev daws teeb meem: 4.8 mg / g ntawm USP Sorbitol RS
Piv txwv li: Dissolve 0.10 g ntawm Sorbitol hauv dej, thiab dilute nrog dej mus rau 20g.Sau qhov kawg daws qhov hnyav, thiab sib tov kom huv si.
Chromatographic system
(Saib Chromatography <621>, System Suitability.)
Qauv: LC
Detector: Refractive Index
Kem: 7.8-mm x 10-cm;kev L34
Kub
Kem: 50 ± 2 °
Ntes: 35 °
Tus nqi ntws: 0.7 mL / min
Kev txhaj tshuaj loj: 10 μL
Qhov system haum
Cov Qauv: Cov kev daws teeb meem tsim nyog thiab cov qauv kev daws teeb meem [CEEB TOOM-Lub sij hawm tuav cov txheeb ze rau mannitol thiab sorbitol yog kwv yees li 0.6 thiab 1.0, feem.]
Suitability xav tau
Kev daws teeb meem: NLT 2.0 ntawm sorbitol thiab mannitol, Kev daws teeb meem tsim nyog
Tus txheeb ze tus qauv sib txawv: NMT 2.0%, Standard tov
Kev tsom xam
Qauv: Cov qauv kev daws teeb meem thiab cov qauv kev daws teeb meem
Xam cov feem pua, ntawm lub hauv paus anhydrous, ntawm D-sorbitol nyob rau hauv ib feem ntawm Sorbitol noj:
Result = (rU/rS) x (CS/CU) x (100/(100 -W)) x 100
rU = ncov teb los ntawm Sample tov
rS = ncov teb los ntawm Standard tov
CS = concentration ntawm USP Sorbitol RS nyob rau hauv Standard tov (mg / g)
CU = concentration ntawm Sorbitol nyob rau hauv cov qauv tov (mg / g)
W = feem pua tau txais hauv kev xeem rau Kev Txiav Txim Dej
Kev lees txais cov qauv: 91.0% -100.5% ntawm lub hauv paus anhydrous
IMPURITIES
• LIMITOF NICKE
Piv txwv li: Dissolve 20.0 g ntawm Sorbitol nyob rau hauv diluted acetic acid, thiab diluted nrog diluted acetic acid rau 150 mL.
Cov tshuaj dawb: 150 mL ntawm diluted acetic acid
Cov txheej txheem kev daws teeb meem: Npaj peb txoj kev daws teeb meem los ntawm kev ntxiv 0.5, 1.0, thiab 1.5 mL ntawm nickel standard tov TS rau 20.0 g ntawm Sorbitol yaj hauv diluted acetic acid, thiab dilute nrog tib cov kuab tshuaj rau 150 mL.
Instrumental mob
(Saib Spectrophotometry thiab Lub Teeb-Scattering <851>)
Hom: Atomic absorption spectrophotometric
Kev ntsuas wavelength: 232.0nm
Lub teeb: Nickel hollow-cathode
Nplaim: Cua-acetylene
Kev tsom xam
Qauv: Cov qauv kev daws teeb meem thiab cov qauv kev daws teeb meem
Rau txhua tus qauv ntxiv 2.0 mL ntawm saturated ammonium pyrrolidinedithiocarbamate tov (muaj 10g / L ntawm ammonium pyrrolidinedithiocarbamate) thiab 10.0 mL ntawm methyl isobutyl ketone, thiab co rau 30 s.Tiv thaiv los ntawm lub teeb ci.Cia ob txheej sib cais, thiab siv cov txheej txheem methyl isobutyl ketone.Teem lub ntsuas rau xoom siv cov organic txheej los ntawm Blank tov.
Concomitantly txiav txim siab absorbances ntawm cov organic txheej los ntawm cov qauv tsawg kawg peb zaug txhua.Sau qhov nruab nrab ntawm cov ntawv nyeem tsis tu ncua rau txhua qhov kev daws teeb meem Standard thiab cov qauv kev daws teeb meem.Nruab nrab ntawm txhua qhov kev ntsuas, aspirate cov organic txheej los ntawm Blank tov, thiab paub tseeb tias qhov kev nyeem ntawv rov qab mus rau xoom.Npaj cov absorbances ntawm Standard daws teeb meem thiab cov qauv tov piv rau ntxiv kom muaj nuj nqis ntawm npib tsib xee.
Extrapolate kab koom nrog cov ntsiab lus ntawm daim duab kom txog rau thaum nws ua tau raws li qhov concentration axis.Qhov kev ncua deb ntawm qhov taw tes no thiab kev sib tshuam ntawm cov axes sawv cev rau qhov concentration ntawm npib tsib xee hauv cov qauv tshuaj.
Kev lees txais: NMT 1 ppm
• RESIDUEON IGNITION <281>: NMT 0.1%, txiav txim siab ntawm 1.5g feem
QHOV TSEEB
[CEEB TOOM-Tus nqi txiav txim siab hauv qhov kev sim no tsis suav nrog hauv cov nyiaj suav nrog hauv Lwm Cov Khoom Siv Hauv Cov Ntawv Ceeb Toom.]
Piv txwv li: Dissolve 3.3 g ntawm Sorbitol hauv 3 mL dej nrog kev pab ntawm maj mam tshav kub.Txias, thiab ntxiv 20.0 mL ntawm khob citrate TS thiab ob peb iav hlaws dai.Tshav kub kom npau npau pib tom qab 4 feeb, thiab tuav lub boil rau 3 feeb.Txias sai sai, thiab ntxiv 40 mL ntawm diluted acetic acid, 60 mL dej, thiab 20.0 mL ntawm 0.05 N iodine VS.Nrog tas li co, ntxiv 25 mL ntawm ib tug sib tov ntawm 6 mL ntawm hydrochloric acid thiab 94 mL dej.
Kev tsom xam: Thaum cov dej nag tau yaj, titrate ntau tshaj ntawm iodine nrog 0.05 N sodium thiosulfate VS siv 2mL ntawm cov hmoov txhuv nplej siab TS, ntxiv rau qhov kawg ntawm titration, raws li qhov taw qhia.
Kev lees txais: NLT 12.8 mL ntawm 0.05 N sodium thiosulfate VS yog xav tau, sib xws rau NMT 0.3% ntawm kev txo cov suab thaj, raws li cov piam thaj.
• CHLORIDEAND SULFATE, Chloride <221> (yog tias sau npe siv rau hauv kev npaj cov ntawv noj tshuaj parenteral)
Qauv: 1.5 g
Kev lees txais cov qauv: Cov qauv qhia tsis muaj cov tshuaj chloride ntau dua li 0.10 mL ntawm 0.020 N hydrochloric acid (NMT 0.0050%).
• CHLORIDEAND SULFATE, Sulfate <221> (yog tias tau sau npe siv rau hauv kev npaj cov ntawv noj tshuaj parenteral)
Qauv: 1.0g
Kev lees txais cov qauv: Cov qauv qhia tsis muaj sulfate ntau dua li 0.10 mL ntawm 0.020 N sulfuric acid (NMT 0.01%).
TSEEM CEEB
• MICROBIAL ENUMERATION TESTS <61> thiab TESTS FOR SPECIFIED MICROORGANISMS <62>: Tag nrho cov suav aerobic siv Plate Method yog NMT 1000 cfu/g, thiab tag nrho cov pwm thiab cov poov xab suav suav yog NMT 100 cfu/g
• PH <791>: 3.5-7.0, hauv 10% (w/w) tov hauv dej tsis muaj carbon dioxide
• KEV TIV THAIV DUA, Txoj Kev I <921>: NMT 1.5%
CLARITYAND COLOROF SOLUTION (yog tias sau npe rau kev siv hauv kev npaj cov ntawv noj tshuaj parenteral)
Qhov hnyav: 10.0 g
Kev Ntsuam Xyuas: Dissolve cov qauv hauv 100.0 mL ntawm cov dej tsis muaj carbon dioxide.
Kev lees txais cov qauv: Cov tshuaj yog ntshiab thiab tsis muaj xim.
• BACTERIAL ENDOTOXINS TEST <85> (yog tias sau npe rau siv hauv kev npaj cov ntawv noj tshuaj parenteral): NMT 4 USP Endotoxin Units/g rau parenteral dosage forms uas muaj ntau dua 100g/L ntawm sorbitol, thiab NMT 2.5 USP Endotoxin Units/g rau cov ntaub ntawv parenteral ntau npaum li cas muaj qhov concentration ntawm 100g / L lossis ntau dua ntawm sorbitol.
TSEEM CEEB
• PACKAGINGAND STORAGE: Khaws rau hauv cov thawv kaw kom zoo.Tsis muaj qhov yuav tsum tau khaws cia.
• LABELING: Sorbitol npaj los siv rau hauv kev npaj cov ntaub ntawv noj tshuaj parenteral yog li sau npe.
USP REFERENCE STANDARDS <11>
Tom ntej: USP Endotoxin RS
USP Sorbitol RS
Pob: Fluorinated Fwj, 25kg / hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias, qhuav thiab cua tshuab kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
D-Sorbitol (CAS: 50-70-4) yog ib qho uas tsis yog-volatile polyhydric qab zib cawv.Nws yog tshuaj ruaj khov thiab tsis yooj yim rau oxidized los ntawm huab cua.Nws yog yooj yim soluble hauv dej, kub ethanol, methanol, isopropanol, butanol cawv, cyclohexanol, phenol, acetone, acetic acid thiab dimethyl formamide.Nws tsis yog yooj yim rau fermented los ntawm ntau yam kab mob thiab muaj ib tug zoo heev tshav kub kuj.Nws yog thawj zaug sib cais los ntawm roob strawberry los ntawm Boussingault (Fabkis) li al.Tus nqi pH ntawm saturated aqueous tov yog 6 mus rau 7. Nws yog isomer ntawm mannitol, Taylor cawv, thiab galactose cawv.Nws muaj ib qho qab zib qab zib nrog qab zib yog 65% ntawm sucrose.Nws muaj peev xwm nqus dej noo zoo heev nrog tus nqi qis calorific thiab muaj ntau yam cuam tshuam rau cov khoom noj, tshuaj pleev ib ce, chaw tshuaj.Thaum siv rau hauv cov khoom noj, nws tuaj yeem tiv thaiv cov zaub mov kom qhuav, kev laus, thiab tuaj yeem txuas ntxiv lub neej txee ntawm cov khoom, nrog rau kev tiv thaiv kom tsis txhob nag lossis daus ntawm cov suab thaj thiab ntsev uas muaj nyob hauv cov khoom noj thiab yog li tuav lub zog sib npaug ntawm qab zib, qaub, iab thiab txhim khu zaub mov tsw.Nws tuaj yeem ua ke los ntawm hydrogenation ntawm cov piam thaj hauv qab cua sov thiab siab siab nrog lub neej ntawm nickel catalyst.
Kev siv tseem ceeb ntawm D-Sorbitol Powder
1. Kev lag luam tshuaj txhua hnub
Sorbitol tuaj yeem siv los ua cov khoom siv ntxiv, cov khoom siv moisturizing, thiab cov tshuaj tiv thaiv kab mob hauv cov tshuaj txhuam hniav, nrog cov nyiaj ntxiv txog li 25 txog 30%.Qhov no tuaj yeem pab tswj lub lubrication, xim, thiab saj zoo rau kev muab tshuaj txhuam.Hauv cov tshuaj pleev ib ce, nws yog siv los ua cov tshuaj tiv thaiv kom qhuav (hloov glycerol) uas tuaj yeem txhim kho qhov ncab thiab lubricity ntawm emulsifier, thiab yog li tsim nyog rau lub sijhawm ntev;Sorbitan esters thiab sorbitan fatty acid ester nrog rau nws cov ethylene oxide adducts muaj qhov zoo ntawm cov tawv nqaij me me uas yog li siv dav hauv kev lag luam tshuaj pleev ib ce.
2. Kev lag luam zaub mov
Sorbitol yog hygroscopic, dej-retaining tus neeg sawv cev uas yog siv nyob rau hauv zus tau tej cov pos hniav thiab confectionery kom zaub mov mos, txhim kho cov nqaij mos thiab txo hardening ntawm cov xuab zeb.Dav siv rau zaub mov, siv los tsim cov khoom qab zib uas tsis yog qab zib thiab cov ntawv kho mob hauv chav kawm (muaj cov khoom).Ntxiv sorbitol rau hauv cov zaub mov tuaj yeem tiv thaiv kom qhuav ntawm cov zaub mov thiab ua kom cov zaub mov nyob twj ywm tshiab thiab mos.Daim ntawv thov nyob rau hauv qhob cij ncuav mog qab zib muaj txiaj ntsig zoo.Sweetener lossis anti-sticking agent ntawm cov pos hniav tsis muaj qab zib, chocolate flavour icing rau ua ice cream thiab khoom qab zib, siv hauv dej haus, khoom qab zib, ci thiab lwm yam khoom noj.
Qhov qab zib ntawm sorbitol yog qis dua li ntawm sucrose, thiab tsis tuaj yeem siv los ntawm cov kab mob.Nws yog ib qho tseem ceeb raw khoom rau kev tsim cov khoom qab zib tsis muaj qab zib thiab ntau yam khoom noj los tiv thaiv kab mob.Txij li thaum cov metabolism hauv cov khoom tsis ua rau cov ntshav qab zib nce ntxiv, nws tuaj yeem siv los ua cov khoom qab zib thiab cov khoom noj khoom haus rau cov zaub mov ntawm cov neeg mob ntshav qab zib.
Sorbitol tsis muaj aldehyde pawg thiab tsis yooj yim oxidized.Nws yuav tsis muaj cov tshuaj tiv thaiv Maillard nrog cov amino acids thaum cua sov.Nws kuj muaj qee yam kev ua physiological.Nws tuaj yeem tiv thaiv qhov denaturation ntawm carotenoids thiab noj cov rog thiab cov protein;ntxiv cov khoom no rau cov kua mis muaj zog tuaj yeem txuas ntxiv lub neej txee;nws kuj tuaj yeem siv los txhim kho cov xim, tsw thiab saj ntawm cov hnyuv me thiab muaj cov nyhuv stabilizing tseem ceeb thiab lub sij hawm ntev cia cov nyhuv ntawm cov ntses pate.Cov nyhuv zoo sib xws kuj tuaj yeem pom hauv jam.
3. Pharmaceutical Industry
Sorbitol tuaj yeem siv los ua raw khoom hauv vitamin C;kuj tuaj yeem siv los ua cov kua txiv hmab txiv ntoo, cov tshuaj txhaj tshuaj, thiab cov khoom siv raw ntawm cov tshuaj ntsiav tshuaj;Raws li cov tshuaj dispersion tus neeg saib xyuas thiab muab tub lim, cryoprotectants, anti-crystallizing agent, tshuaj stabilizers, wetting agents, capsules plasticized agents, sweetening agents, and ointment matrix.
Sorbitol kuj tseem siv rau hauv kev tsim cov softgel capsules los khaws ib koob tshuaj ntawm cov tshuaj ua kua.Kev kho mob rau hyperkalemia (ntshav ntshav potassium) siv sorbitol thiab ion-exchange resin sodium polystyrene sulfonate.
4. Kev lag luam tshuaj
Sorbitol abietin feem ntau yog siv los ua cov khoom siv raw rau cov txheej txheem tsim vaj tsev, kuj tseem siv los ua cov yas thiab cov roj nplaum rau daim ntawv thov hauv polyvinyl chloride resin thiab lwm yam polymers.
Nws tuaj yeem los ntawm txoj hauv kev nrog hlau, tooj liab, thiab txhuas ion hauv alkaline tov los siv rau kev ntxuav thiab tshuaj dawb hauv kev lag luam textile.
Siv sorbitol thiab propylene oxide ua cov khoom pib tuaj yeem tsim cov polyurethane ua npuas ncauj thiab muaj qee cov nplaim hluav taws.
5. Kev lag luam tshuaj pleev ib ce:
Nyob rau hauv tshuaj pleev ib ce txoj hauj lwm dav daim ntawv thov.
Lub sorbitol yog ib hom tshuaj muaj peev xwm ua tau zoo, nws muaj ntau yam kev ua haujlwm hauv cov zaub mov, tshuaj txhua hnub, tshuaj thiab lwm yam, thiab tuaj yeem siv tau raws li lub qab zib saj, excipient, antiseptic thiab lwm yam, ib txhij muaj cov khoom noj khoom haus polyols superiority, xws li tsis tshua muaj nqi hluav taws xob, tsis tshua muaj suab thaj, tiv thaiv cov nyhuv thiab lwm yam.
6. D-Sorbitol tuaj yeem siv los ua cov khoom qab zib rau cov neeg mob ntshav qab zib.Nws muaj kev txuag hluav taws xob zoo, acid tsis kam thiab tsis-fermentability.
7. Lwm tus:
Txhawm rau hloov glycerin los tsim cov tshuaj txhuam hniav, mannitol polyurethane, mannitol anhydride oleate, electrolytic tov ntawm electrolytic capacitors, thiab cov kab lis kev cai zoo rau qee yam kab mob.
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D-Sorbitol CAS 50-70-4 Assay 97.0 ~ 100.5% Khoom...
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D-(-)-Leucinol CAS 53448-09-2 Purity > 98.5% (GC ...
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D-(-)-Ribose CAS 50-69-1 Assay 97.0 ~ 102.0% AJI ...
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D-(-)-Tartaric Acid CAS 147-71-7 Assay 99.5% ~ 10...
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Diethyl D-(-)-Tartrate CAS 13811-71-7 Purity ≥9...
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Benzyl D-(-)-Mandelate CAS 97415-09-3 Assay ≥98...
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(R)-(-)-Methyl Mandelate;Methyl D-(-)-Mandela...
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DL-Alanine CAS 302-72-7 (H-DL-Ala-OH) Assay 98....
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D-Phenylalanine CAS 673-06-3 (HD-Phe-OH) Kev Tshawb...
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L-Carnosine CAS 305-84-0 (β-Alanyl-L-Histidine) ...
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D-Alaninol CAS 35320-23-1 (HD-Ala-Ol) Purity >...
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D-Prolinol CAS 68832-13-3 Purity > 99.0% (GC) E....
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L-Tryptophan CAS 73-22-3 (H-Trp-OH) Kev Ntsuas 98.5 ~ ...
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Inosine CAS 58-63-9 Assay 98.0 ~ 102.0% Hoobkas H...