Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Hoobkas Zoo
Muab khoom nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1 Nr
Skeletal Muscle Relaxant.Calcium Channel Inhibitor
API High Quality, Commercial Production
| Tshuaj npe | Dantrolene Sodium ntsev Hydrate |
| Synonyms | 1- [5-(4-Nitrophenyl) furfurylideneamino] hydantoin Sodium ntsev Hydrate |
| CAS Nr | 14663-23-1 |
| CAT Number | RF-API 78 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
| Molecular Formula | C14H11N4NaO5 |
| Molecular Luj | 338.25 Nws |
| Solubility | Soluble hauv DMSO |
| Shipping Condition | Shipped nyob rau hauv ambient kub |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Yellowish-txiv kab ntxwv rau txiv kab ntxwv crystalline hmoov.Tsis pom muaj pov thawj ntawm kev kis kab mob los ntawm txawv teb chaws |
| Kev Taw Qhia A | IR Absorption (197K) |
| Kev Qhia B | Lub sijhawm khaws cia ntawm lub ncov loj hauv chromatogram ntawm kev tshuaj ntsuam kev npaj sib raug rau qhov hauv chromatogram ntawm tus qauv npaj, raws li tau txais hauv qhov kev xeem |
| Kev txheeb xyuas C | Ua tau raws li qhov yuav tsum tau ua ntawm cov nplaim hluav taws rau Sodium (191) |
| Kev Taw Qhia D | Ntu 1: Ib qho voluminous, dawb, crystalline precipitate yog tsim Ntu 2: Cov nag lossis daus tsis ploj Ntu 3: Lub precipitate dissolves kiag li Ntu 4: Tsis muaj nag lossis daus |
| Cov ntsiab lus dej (los ntawm KF) | 14.5% ~ 17.0%. |
| Particle Loj | 90% tsawg dua 200um |
| Assay | 90.0% ~ 96.0% ntawm C14H10N405 ntawm lub hauv paus anhydrous |
| Yam khoom muaj feem | (HPLC, cheeb tsam%) |
| Related Compound A | ≤ 0.15% |
| Related Compound B | ≤0.50% |
| Related Compound C | ≤ 0.30% |
| Residual Solvents | |
| Ethanol | ≤2000ppm |
| Methanol | ≤2000ppm |
| Acetone | ≤2000ppm |
| DMF | ≤620ppm |
| Hnyav Hlau | ≤10ppm |
| Txee lub neej | 2 Xyoo |
| Test Standard | Tebchaws Asmeskas Pharmocopoeia (USP) |
| Kev siv | Skeletal Muscle Relaxant.Calcium Channel Inhibitor |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), yog ib qho me me molecule inhibitor ntawm Ryanodine receptor antagonist thiab Calcium channel inhibitor.Dantrolene Sodium Salt yog cov leeg pob txha relaxant, uas inhibits intracellular Ca 2 + tso tawm los ntawm sarcoplasmic reticulum.Blockade ntawm Ca2 + tso tawm los ntawm sarcoendoplasmic reticulum, muaj feem xyuam rau excitation thiab contraction ntawm cov nqaij ntshiv, generates ib tug nqaij relaxant nyhuv correlated nrog Dantrolene.Cov neurotoxicity nthuav tawm los ntawm kev hais tawm glutamate muaj feem cuam tshuam rau kev nce siab hauv cytoplasmic Ca2+ qib, thiab Dantrolene tau qhia raws li tus neeg saib xyuas neuroprotective tiv thaiv neurotrasmitter-induced excitotoxicity.Dantrolene, Sodium ntsev yog ib qho inhibitor ntawm RyR-1 thiab RyR-3.
