Darunavir CAS 206361-99-1 Anti-HIV Purity ≥99.0% API Siab Purity HIV Protease Inhibitor
Chaw tsim khoom SupplyDarunavir Yam Khoom:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Tshuaj npe | Darunavir |
| Synonyms | TMC 114;UA-94017 |
| CAS Nr | 206361-99-1 |
| CAT Number | RF-API 68 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
| Molecular Formula | C27H37N3O7S |
| Molecular Luj | 547.66 ib |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
| Kev txheeb xyuas | MS/HNMR HPLC |
| Solubility | Soluble hauv DMSO, me ntsis Soluble hauv dej |
| Melting Point | 74.0 ~ 76.0 ℃ |
| Kev txheeb xyuas | 1 H NMR |
| Purity / Analysis Method | ≥99.0% (HPLC) |
| Yam khoom muaj feem | |
| Max ib leeg impurity | ≤ 0.30% |
| Tag nrho cov impurities | ≤ 1.0% |
| Residual Solvents | Ethanol ≤0.30% |
| Poob rau ziab | ≤0.50% |
| Residue ntawm Ignition | ≤0.10% |
| Hnyav Hlau | ≤ 20ppm |
| Arsenic | ≤1.5ppm |
| Test Standard | Enterprise Standard |
| Kev siv | Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor Anti-HIV |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard Nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Darunavir (lub npe npe Prezista, yav tas los hu ua TMC114) yog cov tshuaj tiv thaiv kab mob protease siv los kho tus kab mob HIV.Darunavir yog OARAC pom zoo xaiv kev kho mob rau kev kho mob-naive thiab kev kho mob-kev paub txog cov neeg laus thiab cov tub ntxhais hluas.Darunavir yog ib yam tshiab uas tsis yog peptide anti retroviral protease inhibitors hauv kev kho mob AIDS.Nws yog thawj zaug tsim los ntawm Johnson kws kho mob Iceland ceg, Tibotec.Nws yog cov bioavailability siab tshaj plaws nyob rau hauv 6 protease inhibitors (saquinavir, ritonavirir, indinavir, naphthalene nelfinavir, amprenavir thiab ABT378 / r).Nws ua los ntawm kev thaiv kev tsim cov kab mob tshiab thiab paub tab los ntawm qhov chaw ntawm cov kab mob hauv lub cev thiab inhibiting tus kab mob protease.Thaum cov khoom siv rau lub sijhawm ntev, nws feem ntau tuaj yeem txo cov kab mob HIV kab mob hauv cov ntshav, nce cov CD4 hlwb, txo cov kab mob HIV, txhim kho lub neej zoo thiab ua kom lub neej ntev.Nws tsim nyog rau cov neeg laus uas muaj tus kab mob HIV tab sis tsis muaj kev cuam tshuam rau kev siv cov tshuaj tiv thaiv kab mob uas twb muaj lawm.Cov tshuaj yuav tsum tau ua ke nrog kev siv tshuaj tsawg ntawm ritonavir lossis lwm yam tshuaj tiv thaiv kab mob, txhawm rau txhim kho kev ua tau zoo.Cov tshuaj tiv thaiv kab mob hauv vitro tuaj yeem raug soj ntsuam los ntawm kev tiv thaiv tus mob hnyav thiab mob ntev lymphocytes thiab lymphocytes hauv cov ntshav peripheral.
