Decitabine CAS 2353-33-5 Purity > 99.5% (HPLC) Hoobkas
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Decitabine (CAS: 2353-33-5) nrog cov khoom zoo.Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, me me thiab ntau ntau.Yog tias koj txaus siab rau cov khoom no, thov xa cov ncauj lus kom ntxaws suav nrog CAS naj npawb, cov khoom npe, kom muaj nuj nqis rau peb.Please contact: alvin@ruifuchem.com
| Tshuaj npe | Decitabine |
| Synonyms | 5-Aza-2'-Deoxycytidine;5-Aza-1-(2-Deoxy-β-D-Ribofuranosyl) cytosine;5-Aza-CdR;5-Aza-dC;5-Deoxy-2'-Azacytidine;ZdCyd;DAC;β-Decitabine |
| CAS Nr | 2353-33-5 : kuv |
| CAT Number | TIAB SA 2728 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C8H12N4O4 |
| Molecular Luj | 228.21 Nws |
| Melting Point | 191 ℃ (txog.) |
| rhiab heev | Cua Sensitive, Thaum tshav kub kub Sensitive |
| Solubility | Dissolved hauv DMSO;Me ntsis Soluble hauv dej |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
| Kev Taw Qhia A | IR: Tus qauv IR Spectrum sib haum nrog tus qauv |
| Kev Qhia B | HPLC: Lub RT ntawm Qhov Loj Peak ntawm Kev Ntsuas Kev Ntsuas Zoo sib xws rau cov txheej txheem daws teeb meem |
| Kev txheeb xyuas C | PXRD: Zoo |
| Purity / Analysis Method | > 99.5% (HPLC) |
| Alpha | +56.0° ~ 63.0° |
| Poob rau ziab | <0.50% |
| Residue ntawm Ignition | <0.10% |
| Hnyav Hlau | <20 ppm |
| Yam khoom muaj feem | |
| α-Decitabine | <0.20% |
| Ib Unknown Impurity | <0.20% |
| Tag nrho cov impurities | <0.50% |
| Residual Solvents | |
| DMSO | <0.50% |
| Methanol | <0.30% |
| Methyl Formate | <0.05% |
| Cov tshuaj acetonitrile | <0.041% |
| Solubility | Colorless Clear 50 mg/ml, HOAc thiab H2O (1: 1) Pass |
| Test Standard | Enterprise Standard |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Yuav Yuav Li Cas?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Russia, Kauslim Teb, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Decitabine (CAS: 2353-33-5) (lub npe lag luam Dacogen), los yog 5-Aza-2'-Deoxycytidine.Chemically, nws yog cytidine analogue.Decitabine yog ib qho tshuaj hypomethylating.Decitabine tau tshaj tawm rau kev kho mob myelodysplastic syndromes (MDS).MDS yog cov kab mob hematologic uas cuam tshuam rau cov pob txha pob txha uas ua rau muaj kev tsim tsis zoo thiab kev loj hlob ntawm cov ntshav.Tsis tas li ntawd, cov neeg mob MDS muaj kev pheej hmoo siab ntawm kev loj hlob mus rau mob myeloid leukemia (AML).Cov kev kho mob ib txwm muaj xws li kev tso ntshav, ntshav hematopoietic kev loj hlob, thiab tshuaj tua kab mob prophylactic, tab sis cov kev ntsuas no tsuas yog txhim kho lub neej zoo nrog cov lus nug txog kev hloov kho kab mob.Txawm hais tias kev hloov pauv ntawm qia-cell yog ib qho kev txhoj puab heev, muaj peev xwm kho tau, lub hnub nyoog siab tshaj lossis lwm yam teeb meem kev noj qab haus huv ntawm cov neeg mob feem ntau txwv tsis pub lawv xav txog qhov kev xaiv no.Kev nce qib tsis ntev los no hauv cov hauv paus etiology ntawm MDS, txawm li cas los xij, tau ua rau kev txhim kho cov chav kawm tshiab ntawm cov tshuaj hu ua "demethylating agents".Decitabine ua raws li kev qhia ua tiav ntawm thawj DNA methyltransferase inhibitor Azacitidine.Nws hypomethylates DNA los ntawm inhibiting DNA methyltransferase.Nws ua haujlwm zoo ib yam li Azacitidine, txawm hais tias decitabine tsuas tuaj yeem muab tso rau hauv DNA strands thaum azacitidine tuaj yeem muab tso rau hauv ob qho tib si DNA thiab RNA chains.Kev tshawb fawb reagents: Decitabine yog siv dav hauv molecular biology, pharmacology, thiab lwm yam kev tshawb fawb.Decitabine raws li ib tug tshwj xeeb DNA methyltransferase inhibitor, reversible DNA methylation txheej txheem, induced qog hlwb rau ib txwm hlwb kom sib txawv los yog induce qog cell apoptosis.Ua siab zoo nco ntsoov tias qhov siab ntawm Decitabine yuav ua rau nws cov nyhuv cytotoxic: tuaj yeem cuam tshuam DNA synthesis induced cell tuag.
