Despropionyl Ramelteon Hydrochloride CAS 196597-80-5 Purity > 98.0% (HPLC)
Tuam Tshoj Chaw tsim tshuaj paus thiab tsum
Intermediates ntawm Ramelteon:
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-one CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
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Tshuaj npe | (S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl)ethylamine Hydrochloride |
Synonyms | Despropionyl Ramelteon Hydrochloride;(S)-2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride;(S)-2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine HCl;Ramelteon impurity 15 HCl;Ramelteon Amine impurity |
CAS Nr | 196597-80-5 |
CAT Number | TIAB SA 2888 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C13H17NO.HCl |
Molecular Luj | 239.74 ib |
Melting Point | 270 ℃ |
Solubility hauv dej | Soluble hauv Chloroform, Dichloromethane, Ethyl Acetate, Methanol |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Solid Powder |
Purity / Analysis Method | > 98.0% (HPLC) |
Poob rau ziab | <1.00% |
Ib leeg Impurity | <1.00% |
Tag nrho cov impurities | <2.00% |
1 H NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate of Ramelteon (CAS: 196597-26-9) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
(S)-2-(1,6,7,8-Tetrahydro-2H-Indeno[5,4-b]furan-8-yl)ethylamine Hydrochloride, los yog Despropionyl Ramelteon Hydrochloride (CAS: 196597-80-5) ) yog ib qho nruab nrab ntawm Ramelteon (CAS: 196597-26-9).Ramelteon (TAK-375) yog ib qho tshiab melatonin receptor agonist rau tib neeg MT1 thiab MT2 receptors thiab nqaij qaib forebrain melatonin receptors nrog Ki ntawm 14 pM, 112 pM thiab 23.1 pM, feem.Lub melatonin molecule tau hloov pauv feem ntau los ntawm kev hloov cov nitrogen ntawm lub nplhaib indole nrog cov pa roj carbon monoxide kom muab lub nplhaib indane thiab los ntawm kev sib xyaw 5-methoxyl pawg hauv lub nplhaib indole rau hauv lub nplhaib furan nruj dua.Qhov kev xaiv ntawm qhov tshwm sim Ramelteon rau MT1 receptor iseight lub sij hawm ntau dua li ntawm MT2 receptor.Tsis zoo li melatonin, nws muaj txiaj ntsig zoo hauv kev pib pw tsaug zog (MT1 kev ua si) dua li hloov kho lub circadian atherosclerosis (MT2 kev ua si).Nws pom tau tias muaj txiaj ntsig zoo dua li melatonin tab sis tsis muaj txiaj ntsig zoo dua li benzodiazepines raws li hypnotic.Qhov tseem ceeb, cov tshuaj no tsis muaj kev lav phib xaub (nws tsis yog cov tshuaj tswj hwm).Yog li ntawd, nws tsis ntev los no tau pom zoo rau kev kho mob ntawm insomnia.