Desquinolinyl Lenvatinib CAS 796848-79-8 Purity > 99.0% (HPLC) Lenvatinib Mesylate Intermediate Factory
Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Nrog Siab Purity
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Tom ntej: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Tom ntej: Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Tom ntej: Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Tshuaj npe | 1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea |
Synonyms | Desquinolinyl Lenvatinib;Lenvatinib Impurity 16;Lenvatinib Desquinolinyl Impurity;Lenvatinib Impurity LFS-A;Lenvatinib Mesylate Intermediate Ⅲ;N-(2-Chloro-4-Hydroxyphenyl)-N'-Cyclopropyl-Urea |
CAS Nr | 796848-79-8 |
CAT Number | RF-PI 1972 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C10H11ClN2O2 |
Molecular Luj | 226.66 ib |
Boiling Point | 364.6 ± 42.0 ℃ |
Qhov ntom | 1.43 ± 0.10g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Off-White to Reddish Brown Solid Powder |
Purity / Analysis Method | > 99.0% (HPLC) |
Moisture (KF) | <0.50% |
Residue ntawm Ignition | <0.20% |
Ib leeg Impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Hnyav Hlau | <10ppm |
Infrared Spectrum | Raws li tus qauv |
NMR | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Lenvatinib Mesylate (CAS: 857890-39-2) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea, tseem hu ua Desquinolinyl Lenvatinib, (CAS: 796848-79-8) yog ib qho nruab nrab lossis impurity ntawm Lenvatinib Mesylate (CAS: 857890-39-2).Desquinolinyl Lenvatinib yog ib qho metabolite ntawm Lenvatinib Mesylate uas yog qhov ncauj qhov ncauj inhibitor ntawm ntau yam receptors tyrosine kinases nrog rau VEGF, FGF thiab SCF receptors.Lenvatinib yog ib qho tshuaj tiv thaiv kab mob qog noj ntshav rau kev kho mob ntawm qee yam qog nqaij hlav qog noj ntshav, thiab muaj feem cuam tshuam rau lwm yam qog noj ntshav thiab.Thaum Lub Ob Hlis 13, 2015, US FDA tau pom zoo tshuaj tiv thaiv kab mob Lenvatinib rau kev kho mob qog noj ntshav.Lenvatinib yog ntau lub hom phiaj enzyme inhibitor, muaj peev xwm inhibiting VEGFR2 thiab VEGFR3 (vascular endothelial kev loj hlob receptor).Lub npe lag luam ntawm Lenvatinib yog Lenvima.