Diethylphosphonoacetic Acid CAS 3095-95-2 Purity > 99.5% (HPLC) Afatinib Dimaleate Intermediate Hoobkas Featured duab

Diethylphosphonoacetic Acid CAS 3095-95-2 Purity > 99.5% (HPLC) Afatinib Dimaleate Intermediate Factory

Lus piav qhia luv luv:

Lub npe tshuaj: Diethylphosphonoacetic Acid

CAS: 3095-95-2 Nr

Purity:> 99.5% (HPLC)

Cov tsos: Xim tsis muaj kua

Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com

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Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Intermediates ntawm Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
Tom ntej: Dimethylamino Acetaldehyde Diethyl Acetal CAS 3616-56-6
Tom ntej: Trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-ib CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS Nr .: 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS Nr .: 314771-88-5

Chemical Properties:

Tshuaj npe	Diethylphosphonoacetic acid
Synonyms	2- (Diethoxyphosphoryl) acetic acid;(Diethoxyphosphinyl) acetic acid;Diethyl Carboxymethylphosphonate;TIAB SA 272281
CAS Nr	3095-95-2 : kuv
CAT Number	Tus Qauv Zauv: RF-PI2024
Tshuag xwm txheej	Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 30MT / Lub Hlis
Molecular Formula	(C2H5O)2P(O)CH2CO2H
Molecular Luj	196.14 Nws
Boiling Point	150 ℃ / 0.05 mmHg (lit.)
Qhov ntom	1.220 g / mL ntawm 25 ℃ (lit.)
Refractive Index	n20/D 1.445 (lit.)
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Xim tsis muaj kua
Kev txheeb xyuas (HPLC)	Lub sijhawm khaws cia ntawm lub ntsiab ncov tau los ntawm cov qauv yog nyob rau hauv 5% ntawm cov qauv siv.
Purity / Analysis Method	> 99.5% (HPLC)
Infrared Spectrum	Raws li tus qauv
Proton NMR Spectrum	Raws li tus qauv
Moisture (KF)	<0.50%
Tag nrho cov impurities	<0.50%
Test Standard	Enterprise Standard
Kev siv	Intermediate of Afatinib Dimaleate (CAS: 850140-73-7)

Pob & Cia:

Pob: Fluorinated Fwj, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

Diethylphosphonoacetic Acid (CAS: 3095-95-2), Ua raws li ib tug nucleophile rau nucleophilic ntxiv tshuaj tiv thaiv rau synthesis ntawm allene epoxides Reactant rau: Stereoselectivity kev tshawb fawb ntawm cov tshuaj tiv thaiv Staudinger;Enantioselective tsim ntawm diols ntawm epoxidation thiab hydration tshuaj tiv thaiv;Horner-Wadsworth-Emmons cov tshuaj tiv thaiv;Tej thaj chaw deb chelation tswj Ireland-Claisen rearrangement;Ugi-Dieckmann cov tshuaj tiv thaiv rau kev sib txuas ntawm tetramic acid derivatives;Siv los ua phosphonoester intermediates rau intramolecular HEW cov tshuaj tiv thaiv.Diethylphosphonoacetic Acid yog ib qho nruab nrab ntawm Afatinib Dimaleate (CAS: 850140-73-7).Afatinib Dimaleate tau pom zoo los ntawm US Food and Drug Administration (FDA) hauv 2013 rau kev kho mob ntawm cov qog nqaij hlav tsis me me (NSCLC).Tshwj xeeb, nws tau pom zoo rau cov neeg mob uas nthuav tawm cov qog metastatic NSCLC uas muaj cov kab mob epidermal growth factor receptor (EGFR) exon deletions lossis exon 21 kev hloov pauv.Afatinib Dimaleate yog covalent inhibitor ntawm ErbB tyrosine kinases (tyk), uas downregulates ErbB signaling los ntawm irreversible binding ntawm EGFR tyk binding qhov chaw.