(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6 Purity > 99.0% (GC) Afatinib Dimaleate Intermediate Factory
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Tshuaj npe | (Dimethylamino) acetaldehyde Diethyl Acetal |
Synonyms | 2,2-Diethoxy-N, N-Dimethylethylamine;N-(2,2-Diethoxyethyl) dimethylamine;2,2-Diethoxy-N, N-Dimethylethan-1-Amine |
CAS Nr | 3616-56-6 |
CAT Number | Qauv TSIS MUAJ: RF-PI2031 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C8H19 NPO 2 |
Molecular Luj | 161.25 Nws |
rhiab heev | Moisture Sensitive |
Boiling Point | 60 ℃ / 5 mmHg |
Flash Point | 45 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Colorless Clear kua |
Purity / Analysis Method | > 99.0% (GC) |
Refractive Index N20/D | 1.410-1.414 Nws |
Lub ntiajteb txawj nqus (20/20 ℃) | 0.865-0.870 Nws |
Proton NMR Spectrum | Raws li tus qauv |
Tag nrho cov impurities | <1.00% |
Heavy Metals (raws li Pb) | ≤ 20ppm |
Test Standard | Enterprise Standard |
Kev siv | Pharmaceutical Intermediates;Afatinib Dimaleate;Sumatriptan |
Pob: Fluorinated Fwj, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
(Dimethylamino)acetaldehyde Diethyl Acetal (CAS: 3616-56-6) yog siv los ua tshuaj intermediates.(Dimethylamino)acetaldehyde Diethyl Acetal tuaj yeem siv rau hauv kev sib txuas ntawm Afatinib Dimaleate (CAS: 850140-73-7), Sumatriptan (CAS: 103628-46-2).Afatinib (lub npe lag luam Gilotrif hauv Asmeskas thiab Giotrif hauv Tebchaws Europe, yav dhau los Tomtovok thiab Tovok) yog cov tshuaj pom zoo hauv Tebchaws Meskas, Europe, Taiwan, Mexico, Chile thiab Nyiv thiab lwm lub tebchaws rau thawj kab kev kho mob ntawm cov neeg mob sib txawv. hom metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), tsim los ntawm Boehringer Ingelheim.Afatinib ua raws li qhov tsis tuaj yeem hloov pauv covalent inhibitor ntawm thereceptor tyrosine kinases epidermal growth factor receptor (EGFR) thiab erbB-2 (HER2).Sumatriptan yog thawj triptan pom zoo (1991) rau kev kho mob ntawm migraine mob taub hau.Nws muaj qhov lowestoral bioavailability ntawm tag nrho cov triptans vim nws lowlipophilicity.Muaj ntau ntau hom tshuaj sib txawv (piv txwv li, ib ntsiav tshuaj ntawm qhov ncauj, SC txhaj tshuaj, tshuaj tua kab mob hauv qhov ntswg, thiab tshuaj suppository) tso cai rau qhov yooj yim ntawm kev kho mob rau cov kev xav tau ntawm tus neeg mob, yog li ua rau sumatriptans yog ib qho tshuaj zoo heev rau kev kho mob migraine. mob taub hau.Sumatriptan kuj tseem muaj qhov ua tau sai heev ntawm kev txhaj tshuaj SC lossis tshuaj tsuag qhov ntswg.