Docetaxel CAS 114977-28-5 Kev Ntsuas 98.0% ~ 102.0%
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Docetaxel (Taxotere) (CAS: 114977-28-5) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, kev pabcuam zoo heev, me me thiab ntau ntau muaj.Yuav Docetaxel,Please contact: alvin@ruifuchem.com
| Tshuaj npe | Docetaxel |
| Synonyms | Taxotere;Taxotere Anhydrous;Docetaxel Anhydrous;N-Debenzoyl-N-tert-Butoxycarbonyl-10-Deacetyltaxol;PIB - 56976 |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Ntau Lawm |
| CAS Nr | 114977-28-5 |
| Molecular Formula | C43H53NO14 |
| Molecular Luj | 807,89 g / mol |
| Melting Point | 186.0 ~ 192.0 ℃ (lub kaum hli ntuj) |
| Qhov ntom | 1.38 ib |
| Solubility | Soluble heev hauv Acetone, Dimethylformamide.Soluble hauv Ethanol, Dichloromethane, Methanol.Insoluble hauv dej |
| COA & MSDS | Muaj |
| Keeb kwm | Shanghai, Suav |
| Hom | Ruifu Tshuaj |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb Crystalline hmoov | Dawb Crystalline hmoov |
| Kev txheeb xyuas | IR & HPLC | Ua raws |
| Kev sib hloov tshwj xeeb [a]20/D | -42.0° to -45.0° (C = 1 in EtOH) | -43.1° Nws |
| Poob rau ziab | <3.00% | 2.05% |
| Residue ntawm Ignition | <0.10% | 0.04% |
| Heavy Metals (Pb) | ≤ 20ppm | <20 ppm |
| Arsenic (As) | ≤1.5ppm | <1.5ppm |
| Yam khoom muaj feem | ||
| Qhov siab tshaj plaws ib leeg impurity | <0.50% | <0.50% |
| Tag nrho cov impurities | <1.00% | <1.00% |
| Microbial Limit Tests | ||
| TAMC | ≤100cfu / g | <100cfu/g |
| TYMC | ≤10cfu/g | <10cfu/g |
| Cov kab mob endotoxins | ≤ 0.3IU / mg | <0.3IU/mg |
| Assay / Analysis Method | 98.0% ~ 102.0% (Ntawm Anhydrous thiab Solvent-Free Basis) | 100.9% |
| Xaus | Cov khoom tau raug kuaj thiab ua raws li cov lus qhia tshwj xeeb | |
Pob:Fluorinated Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, lossis raws li cov neeg siv khoom xav tau.
Cia:Khaws lub thawv kaw kom nruj thiab khaws cia rau hauv qhov chaw txias, qhuav (2 ~ 8 ℃) thiab lub tsev tso cua txias kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.Incompatible nrog muaj zog oxidizing neeg sawv cev.
Shipping:Xa mus thoob ntiaj teb los ntawm huab cua, los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Hazard Symbols Xi - Irritant
Risk Codes
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R61 - Tej zaum yuav ua rau muaj mob rau tus menyuam hauv plab
Kev nyab xeeb piav qhia
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36/37 - Hnav cov khaub ncaws tiv thaiv thiab hnab looj tes tsim nyog.
S53 - Tsis txhob raug - tau txais cov lus qhia tshwj xeeb ua ntej siv.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg los tau.)
UN IDs 1544
WGK Germany 3
TIAB SA 4172750
HS Code 2932999029
Hazard Class 6.1(b)
Packing Group III
Toxicity LD50 intravenous in aub: 2500ug/kg
Docetaxel (Taxotere) (CAS: 114977-28-5) muag li Taxotere lossis Docecad, yog ib qho tshuaj tiv thaiv mitotic chemotherapy uas ua haujlwm los ntawm kev cuam tshuam nrog kev faib cell.Docetaxel tau pom zoo los ntawm FDA rau kev kho mob qog noj ntshav hauv zos lossis mob qog noj ntshav, mob qog noj ntshav hauv lub taub hau thiab caj dab, mob qog noj ntshav, mob qog nqaij hlav qog nqaij hlav prostate thiab cov qog nqaij hlav qog nqaij hlav me me.Docetaxel tuaj yeem siv los ua ib tus neeg sawv cev lossis ua ke nrog lwm cov tshuaj kws khomob raws li qhia nyob ntawm seb hom mob qog noj ntshav thiab theem twg.Docetaxel yog ib tug tswv cuab ntawm pawg tshuaj taxane, uas kuj muaj xws li cov tshuaj chemotherapeutic paclitaxel.Txawm hais tias docetaxel tseem tshuav ob zaug li muaj zog li paclitaxel (vim docetaxel cov nyhuv ntawm lub centrosome ntawm mitotic spindle), ob lub taxanes tau pom tias muaj txiaj ntsig zoo sib xws.Ob peb tsab xov xwm tsis ntev los no tau pom "tsis muaj pov thawj tias cov tshuaj muaj docetaxel tau txais txiaj ntsig ntau dua li cov suav nrog paclitaxel."Txawm hais tias qhov ua tau zoo ntawm ob tus neeg ua haujlwm tau pom tias muaj qhov sib npaug, paclitaxel tuaj yeem ua rau muaj kev phiv tsawg dua.Tsis tas li ntawd, nws tau raug sau tseg tias docetaxel yog qhov ua rau cov tshuaj tiv thaiv cellular ntawm ntau yam sib txawv.
1. Docetaxel yog ib qho chaw kho mob zoo tsim tshuaj tiv thaiv mitotic chemotherapy (uas yog, nws cuam tshuam nrog kev faib cell).
2. Docetaxel feem ntau yog siv rau kev kho mob ntawm lub mis, zes qe menyuam, thiab cov qog nqaij hlav tsis me me.
3. Docetaxel muaj FDA pom zoo thov rau kev kho mob ntawm cov neeg mob hauv zos, los yog metastatic mis los yog cov qog nqaij hlav tsis me me uas tau txais kev kho mob anthracycline raws li kws khomob thiab tsis tuaj yeem tiv thaiv kev mob qog noj ntshav lossis rov qab los.Kev pom zoo nyob sab Europe doce-taxel rau kev siv tshuaj hormone-refractory prostate cancer.
4. Docetaxel yog suav hais tias zoo dua, raws li cytotoxic antimicrotubule.
