Doxorubicin Hydrochloride CAS 25316-40-9 API USP Standard Hoobkas High Purity
Chaw tsim tshuaj paus nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Doxorubicin Hydrochloride
CAS: 25316-40-9 Nr
Antitumor Tshuaj tua kab mob.Inhibits DNA Topoisomerase II
API High Quality, Commercial Production
Tshuaj npe | Doxorubicin Hydrochloride |
Synonyms | Doxorubicin HCl;Adriamycin HCL;Hydroxydaunorubicin Hydrochloride |
CAS Nr | 25316-40-9 |
CAT Number | RF-API 38 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C27H30ClNO11 |
Molecular Luj | 579.98 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Txiv kab ntxwv-liab los yog liab crystalline hmoov;Tsis pom muaj pov thawj ntawm kev kis kab mob los ntawm txawv teb chaws |
Solubility | Soluble hauv dej thiab methanol;me ntsis soluble hauv ethanol;xyaum insoluble hauv acetone |
Kev Taw Qhia A | IR spectrum sib raug rau IR spectrum ntawm tus qauv siv |
Kev Qhia B | Lub sijhawm khaws cia ntawm doxorubicin ncov nyob rau hauv chromatogram ntawm Assay kev npaj sib raug rau qhov uas nyob rau hauv chromatogram ntawm Standard npaj, raws li tau txais nyob rau hauv Assay. |
pH | 4.0 ~ 5.5 hli |
Cov ntsiab lus dej | ≤ 4.0% |
Yam khoom muaj feem | |
Doxorubicinol impurity A | ≤0.50% |
Lwm Yam Tsis Paub Tsis Paub | ≤ 0.20% |
Tag nrho Unknown Impurities | ≤0.50% |
Tag nrho cov impurities | ≤ 1.0% |
Assay | 98.0% ~ 102.0% ntawm C27H30ClNO11 suav ntawm cov dej tsis muaj dej, hnyav-dawb hauv paus |
Residual Solvents | |
Acetone | ≤0.50% |
Acetone + Ethanol | ≤ 2.5% |
Methanol | ≤ 0.30% |
Dichloromethane | ≤0.06% |
Test Standard | Teb Chaws Asmeskas Pharmacopeia (USP) Reference Standard |
Kev siv | Active Pharmaceutical Ingredients (API) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
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Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Doxorubicin Hydrochloride (CAS: 25316-40-9) nrog cov khoom zoo.Doxorubicin hydrochloride, cytotoxic anthracycline tshuaj tua kab mob, yog cov tshuaj tiv thaiv kab mob qog noj ntshav.Doxorubicin hydrochloride yog ib qho muaj zog tib neeg DNA topoisomerase I thiab topoisomerase II inhibitor nrog IC50s ntawm 0.8 μM thiab 2.67 μM, feem.Doxorubicin hydrochloride induces apoptosis thiab autophagy.Doxorubicin yog ib tug muaj zog antitumour tus neeg sawv cev tawm tsam ib tug dav spectrum ntawm malignancies, xws li leukemias, sarcomas, cancer ntawm lub mis, me me mob ntsws cancer thiab zes qe menyuam.
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