Entecavir CAS 142217-69-4 API Hoobkas High Quality Anti-HBV
Chaw tsim tshuaj paus Supply nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Entecavir
CAS: 142217-69-4 Nr
Tshuaj tua kab mob siv los kho kab mob siab B
API High Quality, Commercial Production
Tshuaj npe | Entecavir |
Synonyms | 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-ib |
CAS Nr | 142217-69-4 |
CAT Number | RF-API 80 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C12H15N5O3 |
Molecular Luj | 277.28 ib |
Melting Point | 249.0 ~ 252.0 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb Crystalline hmoov |
Identification IR | Lub infraed absorption spectrum ntawm cov qauv kuaj yuav tsum ua raws li tus qauv siv |
Kev txheeb xyuas HPLC | Lub sijhawm khaws cia ntawm cov qauv xeem sib raug raws li tus qauv siv |
pH | 5.5 ~ 7.5 hli |
Specific Optical Rotation | +24.0° - +28.0° (DMF: MeOH = 1:1 C = 1%) |
Yam khoom muaj feem | |
Tag nrho cov impurities | ≤ 0.30% |
Qhov siab tshaj plaws ib leeg impurity | ≤0.10% |
Enantiomer | ≤ 0.20% |
Residual Solvents | |
Methanol | ≤ 0.30% |
Dichloromethane | ≤0.06% |
n-Hexane | ≤ 0.029% |
Tetrahydrofuran | ≤ 0.072% |
N, N-Dimethylformamide | ≤ 0.088% |
Toluene | ≤ 0.089% |
Cov ntsiab lus dej | 5.8% ~ 6.5% |
Residue ntawm Ignition | ≤0.10% |
Hnyav Hlau | ≤ 20ppm |
Assay | 98.0% ~ 102.0% (C12H15N5O3 xam raws li anhydrous) |
Particle Loj | D90: ≤100µm |
Test Standard | Enterprise Standard |
Kev siv | API, Antiviral tshuaj siv los kho kab mob siab B |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Entecavir yog ib tiam tshiab ntawm guanine nucleoside analogues qhov ncauj tshuaj rau kev kho mob ntawm tus kab mob siab B Virus (HBV), feem ntau yog siv rau kev kho mob ntawm cov neeg laus cov neeg mob nrog viral replication ua si thiab serum transaminase txuas ntxiv mus, los yog daim siab cov ntaub so ntswg rau pathological kev ua ntawm tus kab mob siab B. , yog tam sim no cia tus kab mob sai tshaj plaws thiab muaj zog tshaj plaws, qhov hloov pauv tus nqi qis tshaj nucleoside analogues.Cov ntaub ntawv qhia tau hais tias sib txawv ntawm cov neeg mob uas muaj kab mob siab B, suav nrog nucleoside naive thiab nucleoside kho thiab cov neeg mob siab cirrhosis, siv cov ntsiav tshuaj entecavir zoo hauv kev kho mob tuaj yeem tswj tau tus kab mob sai thiab yooj yim mus txog kev kho mob ntawm qhov tseeb, uas yog tus kab mob siab B tsis tau ntsuas;los ntawm kev ua raws li kev kho mob, feem ntau ntawm cov neeg mob tuaj yeem tuaj txog thaum kawg ntawm kev kho mob siab, xws li e antigen serology hloov dua siab tshiab, qee cov neeg mob tuaj yeem ncav cuag qhov zoo tshaj plaws rau kev kho mob kawg, uas yog ntog antigen tsis zoo.