Epalrestat CAS 82159-09-9 Purity > 99.5% (HPLC) Hoobkas
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Epalrestat (CAS: 82159-09-9) nrog cov khoom zoo.Ruifu Chemical tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav Epalrestat,Please contact: alvin@ruifuchem.com
| Tshuaj npe | Epalrestat |
| Synonyms | Epalrest;ONO-2235;Eabeth;Kinedak;Sorbistat;(5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2-[(5Z)-5-[(E)-3-Phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid;(E,E)-2-[5-(2-Methyl-3-phenyl-prop-2-enylidene)-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic acid |
| Tshuag xwm txheej | Hauv Tshuag, Kev Tsim Khoom Loj |
| CAS Nr | 82159-09-9 |
| Molecular Formula | C15H13NO3S2 |
| Molecular Luj | 319,39 g / mol |
| Melting Point | 222.0 txog 226.0 ℃ |
| Qhov ntom | 1.43 ± 0.10g / cm3 |
| Solubility | DMSO 2 mg/mL Dej <1 mg/mL Ethanol <1 mg/mL |
| Cia Temp. | Qhov chaw txias & qhuav (-20 ℃) |
| COA & MSDS | Muaj |
| Qeb | API |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Txiv kab ntxwv rau txiv kab ntxwv liab Crystalline hmoov | Ua raws |
| Kev txheeb xyuas | Zoo ib yam li HPLC tuav lub sij hawm ntawm tus qauv | Hla |
| Melting Point | 222.0 txog 226.0 ℃ | 222.4 ~ 224.3 ℃ |
| Poob rau ziab | <0.50% | 0.04% |
| Residue ntawm Ignition | <0.20% | 0.03% |
| Heavy Metals (Pb) | ≤ 20ppm | <20 ppm |
| Tag nrho cov impurities | ≤0.50% | 0.20% |
| Purity / Analysis Method | > 99.5% (HPLC) | 99.8% |
| Infrared Spectrum | Raws li tus qauv | Ua raws |
| Xaus | Cov khoom tau raug kuaj & ua raws li cov lus qhia tshwj xeeb | |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov txias thiab qhuav (-20 ℃) warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
UN IDs 2811
WGK Germany 3
RTECS XJ5131855
Hazard Chav Kawm 6.1
Packing Group II
Epalrestat (CAS: 82159-09-9) yog tus thib ob aldose reductase inhibitor uas tau tshaj tawm thoob ntiaj teb thiab thawj zaug tau tshaj tawm hauv Nyij Pooj.Epalrestat yog qhia rau kev kho mob ntshav qab zib neuropathy.Nws tseem raug tshuaj xyuas rau ntshav qab zib retinopathy thiab nephropathy.Epalrestat yog ib qho aldose reductase inhibitor nrog IC50 ntawm 72 nM.
Epalrestat inhibits Aldose Reductase (AR) koom nrog hauv tus nqi txwv cov kauj ruam hauv kev hloov pauv cov piam thaj mus rau sorbitol hauv cov xwm txheej hyperglycemic.Aldose reductase tau ua lub hom phiaj ntawm ntau qhov kev tshawb fawb soj ntsuam los kho mob ntshav qab zib neuropathy thiab retinopathy.Epalrestat yog ib qho tshuaj pom zoo hauv Nyiv thiab Is Nrias teb, siv rau kev kho mob ntshav qab zib neuropathy.
Epalrestat yog siv los tiv thaiv, ameliorate, thiab kho cov kab mob peripheral neuropathy (xws li, mob), vibrational paresthesia, thiab plawv abnormality txuam nrog ntshav qab zib.
Epalrestat raws li nws cov tshuaj sawv cev txo qis intracellular tsub zuj zuj ntawm fructose thiab sorbitol los ntawm reversibly inhibiting aldose reductase kev ua, restores Na +-K +-ATPase thiab inositol kev ua, tsub kom tsis muaj tsim nyob rau hauv endothelial hlwb, inhibits protein kinase C signaling pathway, endothelial cell kua nplaum, siab adhesion. mediated neutrophil thiab endothelial adhesion factor qhia thiab txo cov khoom carboxymethyl lysine hauv cov neeg mob ntshav qab zib, yog li kho cov kab mob xws li ntshav qab zib thiab nws cov teeb meem.
