Erlotinib Hydrochloride CAS 183319-69-9 Purity > 99.0% (HPLC) Cov duab tshwj xeeb

Erlotinib Hydrochloride CAS 183319-69-9 Kev Ntshiab > 99.0% (HPLC)

Lus piav qhia luv luv:

Lub npe tshuaj: Erlotinib Hydrochloride

Synonyms: Erlotinib HCl;Tarceva

CAS: 183319-69-9 Nr

Purity (HPLC):> 99.0%

Cov tsos mob: Dawb rau Off-White Crystalline Hmoov

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Xa email rau peb

Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Ua cov chaw tsim khoom thiab cov chaw muag khoom ntawm Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-one CAS 179688-29-0
Please contact: alvin@ruifuchem.com

Chemical Properties:

Tshuaj npe	Erlotinib Hydrochloride
Synonyms	Erlotinib HCl;Tarceva;CP-358774 Hydrochloride;6,7-Bis(2-methoxyethoxy)-4-(3-ethylanilinino) quinazoline Hydrochloride;N-(3-Ethynylphe nyl) [6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine HCl
CAS Nr	183319-69-9
CAT Number	Qauv TSIS MUAJ: RF-PI2242
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C22H24ClN3O4
Molecular Luj	429.90 Nws
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Crystalline Hmoov
Kev txheeb xyuas	A: IR: Sib tham rau Reference Spectrum B: HPLC: Sib Tham rau Reference RT
Solubility	Soluble me ntsis hauv dej, me ntsis soluble hauv Methanol thiab xyaum insoluble hauv Acetonitrile, Acetone, Ethyl Acetate thiab Hexane
Melting Point	223.0 ~ 229.0 ℃
Poob rau ziab	<0.50%
Residue ntawm Ignition	<0.20%
Hnyav Hlau	<20 ppm
Ib leeg Impurity	<0.50%
Tag nrho cov impurities	<1.00%
Residual Solvents
Pyridine	<4000ppm
Chloroform	<4000ppm
DMF	<3000ppm
Purity / Analysis Method	> 99.0%
Assay / Analysis Method	98.5% ~ 101.0% (Cau ntawm Anhydrous Basis)
Test Standard	Enterprise Standard
Kev siv	API

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

Erlotinib Hydrochloride (CAS: 183319-69-9) yog ib tug me me molecule ntawm epidermal loj hlob yam tseem ceeb receptor tyrosine kinase reversible inhibitor, yog tsuas yog siv nyob rau hauv kev kho mob ntawm lub zos advanced los yog metastatic tsis me me cell ntsws cancer thiab thib ob-kab los yog peb kab kev kho mob. mob qog noj ntshav pancreatic.Erlotinib Hydrochloride tau pom zoo nyob rau lub Kaum Ib Hlis, 2004, rau kev kho mob ntawm kev mob qog noj ntshav siab lossis metastatic uas tsis yog mob qog noj ntshav.Nws belongs rau tib chav kawm xws li Gefitinib, lwm quinazoline tau pom zoo rau kev kho mob qog noj ntshav siab, tab sis nrog kev txhim kho pharmacokinetic.Lub molecule tau pib los ntawm Pfizer thiab kev txhim kho pib hauv kev koom tes nrog OSI, uas suav tias muaj cai tag nrho rau cov tshuaj thaum Pfizer koom nrog Warner Lambert.Tom qab ntawd, Genentech / Roche tau mus rau hauv daim ntawv cog lus nrog OSI los tsim thiab ua lag luam cov tshuaj hauv Asmeskas thiab thoob ntiaj teb.Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor.Antineoplastic.Erlotinib Hydrochloride yog HER1 / EGFR inhibitor nrog IC50 ntawm 2 nM.Erlotinib HCl muaj xws li 25-, 100-, thiab 150-mg ntsiav tshuaj rau kev tswj hwm.