Ethyl (S)-4-Chloro-3-hydroxybutyrate CAS 86728-85-0 Atorvastatin Calcium Intermediate
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Tshuaj npe | Ethyl (S)-4-Chloro-3-hydroxybutyrate |
Synonyms | (S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester |
CAS Nr | 86728-85-0 |
CAT Number | Qauv: RF-PI139 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C6H11ClO3 |
Molecular Luj | 166.6 ib |
Qhov ntom | 1.19 g / mL ntawm 25 ℃ (lit.) |
Refractive Index | n20/D 1.453 (lit.) |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Colorless to Pale Yellow Liquid |
Purity / Analysis Method | ≥98.0% (GC) |
Moisture (KF) | ≤0.50% |
Ethyl-4-Chloro Aceto Acetate | ≤0.50% |
Test Standard | Enterprise Standard |
Kev siv | Pharmaceutical Intermediate;Organic Synthesis |
Tom ntej: Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0)
Txoj kev tsom xam
Kev piav qhia
Siv li 10ml qauv hauv lub khob huv thiab qhuav thiab kos.
Kev sib hloov tshwj xeeb
Hloov kom raug li ntawm 1.0g ntawm cov qauv mus rau 100ml volumetric hwj thiab yaj nyob rau hauv10 ml ntawm chloroform, ces dilute nrog chloroform mus rau 100ml thiab sib tov.
Ntsuas qhov kev hloov kho qhov muag ntawm cov qauv ntsuas ntawm 25ºC thiab 589nm wavelengthsuav cov kev sib hloov tshwj xeeb raws li cov qauv muab.
[α]25D = (v×a)/[w×(1-b)]
[α]25D: qhov kev sib hloov ntawm kev xeemqauv;α: qhov pom kev sib hloov hauvangular degree;w: qauv hnyav (g);
v: ntim (mL);
b: Cov ntsiab lus dej (%)
Purity (los ntawm GC)
Chromatographic tej yam kev mob: Gas chromatography yog nruab nrog nplaim tawsionization ntes
Kem: SE-54, 30m × 0.35mm × 0.25µm
Qhov cub kub: Pib kub 120 ℃, Tuav lub sijhawm rau 2 min
Kev kub ceev: 20 ℃ / min
Kub: 250 ℃, Tuav lub sijhawm rau 2 min
Injector kub: 250 ℃
Kev ntsuas kub: 250 ℃ (FID)
Txhaj ntim: 0.2µl
Piv txwv li: dilute 1ml A4 nrog 1ml acetone.
Cov txheej txheem: Txhaj 0.2µl ntawm acetone raws li qhov khoob thiab sau cov chromatogram.Hauvchromatogram tau los ntawm diluent yuav tsum tsis txhob muaj kev cuam tshuam ntawm lubtuav lub sij hawm ntawm lub ntsiab ncov thiab impurity ncov.Tshaj Txhaj cov qauv tshuaj hauvduplicate rau hauv chromatograph thiab sau cov chromatogram.Qhia qhov Purity ntawmcoj mus kuaj los ntawm cheeb tsam normalization txoj kev.
Pob: Lub raj mis, chim, 25kg / chim, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
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Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0) nrog cov khoom zoo, nws yog ib qho nruab nrab feem ntau nyob rau hauv cov synthesis ntawm Atorvastatin. Calcium (CAS: 134523-03-8).
Atorvastatin Calcium (CAS: 134523-03-8) [lub npe lag luam: Lipitor] feem ntau yog qhia rau kev kho mob plawv thiab dyslipidemia vim nws cov txiaj ntsig hauv kev txo cov roj cholesterol hauv cov ntshav.Atorvastatin ua haujlwm feem ntau hauv daim siab.Txo cov roj cholesterol hauv siab ntxiv ua rau lub siab nce siab ntawm cov cholesterol thiab txo cov roj cholesterol hauv cov ntshav.Lipitor, txij li xyoo 1996, tau dhau los ua lub ntiaj teb cov tshuaj muag zoo tshaj plaws rau qhov ntawd.
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