Fmoc-Gly-OH CAS 29022-11-5 Fmoc-Glycine Purity > 99.0% (HPLC) Hoobkas

Fmoc-Glycine (Fmoc-Gly-OH) (CAS: 29022-11-5) yog N-Fmoc-tiv thaiv daim ntawv ntawm Glycine.Glycine yog ib qho tseem ceeb amino acid.Fmoc-amino acids, siv nyob rau hauv peptide synthesis, siv los ua cov organic synthesis intermediate, tshuaj intermediate, biochemical reagent lossis tshuaj reagent.
Taw qhia: Fmoc-Glycine yog Glycine tiv thaiv los ntawm Fmoc.Fluorene methoxycarbonyl (Fmoc) yog ib pab pawg tiv thaiv lub hauv paus, uas tuaj yeem siv rau hauv cov dej ntshiab ammonia lossis dioxane-methanol-4N NaOH (30: 9: 1) thiab piperidine, ethanolamine, cyclohexylamine, 1,4-Dioxane, pyrrolidone thiab lwm yam ammonia 50% dichloromethane tov.Raws li tsis muaj zog alkaline tej yam kev mob xws li sodium carbonate los yog sodium bicarbonate, Fmoc tiv thaiv pab pawg neeg feem ntau yog qhia los ntawm Fmoc-Cl los yog Fmoc-OSu.
Daim ntawv thov: Fmoc-Glycine yog Fmoc-tiv thaiv Glycine, uas yog siv los ua cov polypeptides.Qhov sib txawv ntawm cov amino acid tiv thaiv pawg muaj kev cuam tshuam zoo rau kev ua haujlwm thiab tawm los ntawm polypeptide synthesis.Piv txwv li, Fmoc-Glycine tuaj yeem siv los npaj glycine derivative corrosion inhibitor, thiab Fmoc-tiv thaiv pab pawg thiab hydrophobic ntev saw txuas nrog Glycine molecule los ntawm cov tshuaj tiv thaiv amidation, thiab heteroatom (N, O, thiab lwm yam) los yog. unsaturated bonds) thiab lub nplhaib bisphenyl uas muaj π electrons yog adsorbed ntawm cov hlau, thiab cov saw hlau ntev hydrophobic thaiv cov dej molecules, kom nws tsim cov yeeb yaj kiab tiv thaiv ntawm cov hlau nto kom ua tiav lub hom phiaj ntawm kev tiv thaiv corrosion.
Kev npaj: Fmoc-Glycine synthesis tshwj xeeb cov kauj ruam yog raws li nram no: 3.0g Glycine yog yaj nyob rau hauv 115ml ntawm 10% Na2CO3, txias rau -4 ~ 0 ℃, 11.2g Fmoc-Cl yaj nyob rau hauv 35.0ml ntawm acetone thiab ntxiv rau lub kaw lus dropwise, Tom qab qhov sib ntxiv ntawm dropwise, nplawm hauv dej khov rau 30 feeb, thiab tom qab ntawd nplawm hauv chav sov li 2.0h.Cov tshuaj tiv thaiv kev nce qib tau saib xyuas los ntawm nyias txheej chromatography.Tom qab cov tshuaj tiv thaiv ua tiav, 400ml dej tau nchuav rau hauv dej, ether tau muab rho tawm ob zaug, txias thiab hloov kho rau pH2 nrog concentrated hydrochloric acid, ib qho loj ntawm cov khoom dawb yog precipitated, 50 ml ntawm ethyl acetate tau muab rho tawm peb zaug, anhydrous magnesium. sulfate tau qhuav, hnyav tau distilled nyob rau hauv lub siab txo, thiab roj av ether yog siv los ua precipitate kom tau 11.5g ntawm Fmoc-Glycine.Tom qab purification, purity ntawm cov khoom yog 97.35% los ntawm kev ua haujlwm siab ua kua chromatography.