Fondaparinux Sodium CAS 114870-03-0 API

Lus piav qhia luv luv:

Lub npe tshuaj: Fondaparinux Sodium

CAS: 114870-03-0 Nr

Cov tsos mob: Dawb rau Off-White hmoov

Kev ntsuam xyuas: 95.0% ~ 103.0% (nyob rau hauv qhuav qhuav)

Ib qho Antithrombotic Anticoagulant, Factor Xa Inhibitor

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Muab khoom nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Fondaparinux Sodium
CAS: 114870-03-0 Nr
Ib qho Antithrombotic Anticoagulant, Factor Xa Inhibitor
API High Quality, Commercial Production

Chemical Properties:

Tshuaj npe	Fondaparinux Sodium
CAS Nr	114870-03-0
CAT Number	Tus Qauv Zauv: RF-API84
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms
Molecular Formula	C31H43N3O49S8.10Na
Molecular Luj	1728.08 Nws
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Powder
Assay / Analysis Method	95.0% ~ 103.0% (ntawm qhuav hauv paus)
Solubility	Dawb Soluble hauv dej, 2.0M Sodium Chloride thiab 0.5M Sodium Hydroxide thiab Insoluble hauv Ethanol
ID 13C-NMR	Resonances rau Fondaparinux Sodium yuav tsum raug soj ntsuam ntawm 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 1071.9, pp.Cov tshuaj hloov pauv ntawm cov cim no tsis txawv ntawm ntau dua ± 0.3ppm lwm cov cim ntawm qhov siab sib txawv thiab cov tshuaj hloov pauv, tshwm sim los ntawm Fondaparinux Sodium, tej zaum pom ntawm 58.0 ~ 80.5 ppm thiab 98.7 ~ 104.5ppm
Kev txheeb xyuas HPLC	Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv kev daws teeb meem sib raug rau cov qauv kev daws teeb meem
Identification AAS	Sodium yuav tsum muaj cov yam ntxwv nqus ntawm 330.2nm raws li kev txiav txim siab ntawm sodium
pH	6.0-8.0 Nws
Sodium (Na)	11.5% ~ 15.0% (Xam ntawm cov dej tsis muaj dej thiab cov kuab tshuaj dawb)
Dawb sulfate	≤ 0.30%
Residual Chloride	≤ 1.00%
Yam khoom muaj feem
impurity A	≤ 0.80%
Impurity B	≤ 0.60%
Ib leeg Lwm yam Impurity	≤ 0.30%
Tag nrho cov impurities	≤ 2.00%
Residual Solvents
Methanol	≤3000ppm
Ethanol	≤5000ppm
Ethyl Acetate	≤5000ppm
DMF	≤880ppm
Methylbenzene	≤890ppm
Pyridine	≤ 50ppm
Cov ntsiab lus dej (KF)	≤ 15.0%
Cov kab mob endotoxins	≤ 3.3EU / mg
Microbial txwv	Tag nrho cov kab mob microorganisms ≤100cfu / g
Test Standard	Enterprise Standard;Teb Chaws Asmeskas Pharmacopoeia (USP) Standard
Kev siv	API, Antithrombotic Anticoagulant, Factor Xa Inhibitor

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.

Qhov zoo:

FAQ:

Daim ntawv thov:

Fondaparinux Sodium (CAS 114870-03-0) yog thawj chav kawm tshiab ntawm cov tshuaj antithrombotic anticoagulant uas muaj feem xyuam rau qhov hnyav molecular heparins (LMWH).Fondaparinux sodium yog ib qho tseem ceeb Xa inhibitor los tsim lub siab affinity binding site rau anti-coagulant yam antithrombin III (ATIII).Fondaparinux sodium binding ntawm qhov chaw no potentiates lub ntuj inhibitory nyhuv ntawm ATIII tiv thaiv Factor Xa los ntawm ib qho ntawm kwv yees li 300, uas ua rau inhibition ntawm thrombin tiam.Nws yog ua lag luam los ntawm GlaxoSmithKline.Ib tug generic version tsim los ntawm Alchemia yog ua lag luam nyob rau hauv Teb Chaws Asmeskas los ntawm Dr. Reddy's Laboratories.Fondaparinux sodium yog thawj zaug qhia nyob rau hauv Teb Chaws Asmeskas rau kev tiv thaiv kab mob sib sib zog nqus vein thrombosis uas yuav ua rau pulmonary embolism tom qab kev phais loj orthopedic.Qhov no tag nrho cov hluavtaws molecule yog ib daim qauv ntawm heparin pentasaccharide ib ntus, qhov luv tshaj plaws fragment muaj peev xwm catalyze antithrombin lllmediated inhibition ntawm factor Xa yog li inhibiting thrombin tiam yam tsis muaj antithrombin ua.