Ganciclovir CAS 82410-32-0 API BW 759 GCV Antiviral CMV Inhibitor Siab Zoo
Chaw tsim tshuaj paus Supply nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Ganciclovir
CAS: 82410-32-0 Nr
Antiviral Agent rau Kev Kho Mob ntawm Cytomegalovirus (CMV) Kab Mob
API High Quality, Commercial Production
Tshuaj npe | Gancilovir |
Synonyms | GCV;BW 759;9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine;2-Amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-ib;2'-Nor-2'-Deoxyguanosine |
CAS Nr | 82410-32-0 |
CAT Number | Tus Qauv Zauv: RF-API82 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C9H13N5O4 |
Molecular Luj | 255.23 Nws |
Melting Point | 250 ℃ |
Cia Kub | 2-8 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov |
Solubility | Heev me ntsis soluble nyob rau hauv dej |
Kev txheeb xyuas | Ultraviolet Absorption, Infrared Absorption |
Poob rau ziab | ≤ 6.0% |
Residue ntawm Ignition | ≤0.10% |
Yam khoom muaj feem | Ganciclovir Related Compound A ≤0.50% |
Limit ntawm Guanine | ≤0.50% |
Residual Solvents (GC) | Ethanol ≤5000ppm |
Hnyav Hlau | ≤10ppm |
Absorption Coefficient | 516-548 ntawm 252nm |
Cov kab mob endotoxins | ≤0.84EU/mg |
Assay | 98.0% ~ 102.0% (Titration) |
Test Standard | Enterprise Standard;Teb Chaws Asmeskas Pharmacopoeia (USP) Standard |
Kev siv | API, CMV Inhibitor |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Ganciclovir (CAS 82410-32-0) belongs rau cov tshuaj tua kab mob nucleoside, yog ib hom guanosine derivatives.Ganciclovir yog ib tug parenterally-active antiviral tus neeg sawv cev qhia rau pom- los yog lub neej-kev hem thawj cytomegalovirus (CMV) kab mob nyob rau hauv immunocompromised cov neeg mob.Nws muaj qhov dav dav, muaj txiaj ntsig zoo inhibitory cuam tshuam rau tus kab mob herpes thiab yog thawj cov tshuaj xaiv rau kev kho mob ntawm cytomegalovirus uas muaj zog tiv thaiv kab mob siab B thiab adenovirus ib yam nkaus.Nws yog homologue ntawm acyclovir (ACV) nrog nws cov tshuaj tiv thaiv kab mob zoo ib yam li, tab sis muaj zog dua aciclovir, tshwj xeeb tshaj yog muaj zog inhibitory cuam tshuam rau cytomegalovirus cuam tshuam nrog cov neeg mob AIDS.Nws yog qhov chaw kho mob siv rau kev kho mob ntawm induction theem thiab txij nkawm theem ntawm cov neeg mob immunocompromised (xws li cov neeg mob AIDS) nrog concurrent cytomegalovirus retinitis.Nws tseem tuaj yeem siv rau kev tiv thaiv kab mob cytomegalovirus rau cov neeg mob tau txais kev hloov pauv hauv nruab nrog cev lossis cov neeg mob AIDS nrog cov txiaj ntsig zoo hauv cytomegalovirus serology test.
Ganciclovir (CAS 82410-32-0) yog ib qho ua tau zoo, tsis muaj tshuaj lom thiab xaiv tus kab mob siab uas tsim los ntawm Syntex Company (United States).Nws yog thawj cov tshuaj uas tau pom zoo los ntawm US FDA rau kev kho mob ntawm cytomegalovirus (CMV) kab mob.Syntex tau txais kev tso cai tshwj xeeb ntawm kev tsim khoom.Thaum Lub Rau Hli 1988, cov ntsiav tshuaj no tau pom zoo thawj zaug rau npe hauv tebchaws Askiv, tom qab ntawd tau txais kev pom zoo los ntawm Fabkis, Tebchaws Meskas, Nyiv, thiab Tebchaws Yelemees sab hnub poob, Ltalis thiab Canada thiab lwm lub tebchaws.Txog rau thaum kawg ntawm Lub Rau Hli 1999, nws tau pom zoo nyob hauv ntau dua 70 lub teb chaws thiab cheeb tsam rau kev tiv thaiv cov neeg mob tiv thaiv kab mob thiab kab mob cytomegalovirus ntawm cov neeg mob ntawm kev hloov pauv hauv nruab nrog cev.Hauv xyoo 2002, cov ntsiav tshuaj Ganciclovir tau txais kev pom zoo los ntawm FDA, tau dhau los ua tam sim no.