Glimepiride CAS 93479-97-1 Assay 98.0% ~ 102.0% API Hoobkas High Purity
Muab khoom nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Glimepiride
CAS: 93479-97-1 Nr
Glimepiride hauv kev kho mob ntawm Noninsulin-Dependent Type 2 Diabetes Mellitus
API High Quality, Commercial Production
Tshuaj npe | Glimepiride |
Synonyms | Amaryl |
CAS Nr | 93479-97-1 |
CAT Number | RF-API 24 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C24H34N4O5S |
Molecular Luj | 490.62 ib |
Melting Point | 212.2 ~ 214.5 ℃ |
Shipping Condition | Nyob rau hauv Ambient Kub |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Yuav luag Dawb Hmoov |
Kev txheeb xyuas | IR (zoo ib yam li Standard) |
Yam khoom muaj feem | |
Cis-Isomer (A) | ≤ 0.80% |
Sulfonamide (B) | ≤ 0.40% |
Urethane (C) | ≤0.10% |
3-Isomer (D) | ≤ 0.20% |
Lwm yam impurity | ≤0.10% |
Tag nrho cov impurities | ≤0.50% |
Poob rau ziab | ≤0.50% |
Residue ntawm Ignition | ≤0.10% |
Hnyav Hlau | ≤ 0.001% |
Assay | 98.0% ~ 102.0%. |
Test Standard | European Pharmacopeia (EP);Tebchaws Asmeskas Pharmocopoeia (USP) |
Kev siv | Active Pharmaceutical Ingredients (API) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Glimepiride (CAS: 93479-97-1) nrog cov khoom zoo, cov khoom siv tshuaj nquag (API).Glimepiride yog ib qho tshuaj tua kab mob uas pab tswj cov ntshav qab zib.Glimepiride yog ib qho kev ua haujlwm ntev, thib peb tiam sulfonylurea nrog kev ua haujlwm hypoglycemic.
Glimepiride (lub npe lag luam qub Amaryl) yog qhov ncauj muaj nyob nruab nrab-rau-ntev-ua yeeb yam sulfonylurea antidiabetic tshuaj.Zoo li txhua yam sulfonylureas, glimepiride ua raws li cov tshuaj insulin secretagogue.Nws txo qis cov piam thaj hauv ntshav los ntawm kev txhawb nqa kev tso tawm ntawm insulin los ntawm kev ua haujlwm ntawm pancreatic beta hlwb thiab los ntawm kev ua kom muaj zog ntawm cov ntaub so ntswg peripheral rau insulin.Glimepiride yuav khi rau ATP-sensitive potassium channel receptors ntawm lub pancreatic cell nto, txo cov potassium conductance thiab ua rau depolarization ntawm daim nyias nyias.Membrane depolarization stimulates calcium ion influx los ntawm voltage-sensitive calcium raws.Qhov kev nce ntxiv hauv cov calcium ion concentration hauv intracellular induces qhov tso tawm ntawm insulin.Glimepiride feem ntau yog siv los kho cov neeg mob ntshav qab zib hom 2 thiab tseem tuaj yeem txo qhov kev pheej hmoo uas ib tus neeg yuav muaj teeb meem ntawm hom 2 mob ntshav qab zib.Cov tshuaj tau pom zoo los ntawm FDA hauv 1995 thiab yog tsim los ntawm Sanofi-Aventis.Nws tuaj yeem siv nrog rau kev noj zaub mov kom zoo thiab kev tawm dag zog thiab tuaj yeem siv ib leeg lossis nrog lwm cov tshuaj tiv thaiv kab mob yog tias xav tau.Glimepiride tuaj yeem siv los ua monotherapy lossis ua ke nrog insulin.