HBTU CAS 94790-37-1 Peptide Coupling Reagent Purity > 99.0% (HPLC) Hoobkas

Lus piav qhia luv luv:

Lub npe tshuaj: HBTU

CAS: 94790-37-1 Nr

Purity:> 99.0% (HPLC)

Cov tsos mob: Dawb crystalline hmoov

Peptide Coupling Reagent, Siab Zoo

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Product Detail

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Nqe lus piav qhia:

Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm HBTU (CAS: 94790-37-1) nrog cov khoom zoo.Ruifu Chemical muab cov txheej txheem tiv thaiv reagents thiab coupling reagents.Ruifu tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav HBTU,Please contact: alvin@ruifuchem.com

Chemical Properties:

Tshuaj npe HBTU
Synonyms 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium 3-Oxide Hexafluorophosphate;N, N, N′, N′-Tetramethyl-O-(1H-Benzotriazol-1-yl) uronium Hexafluorophosphate;O-Benzotriazole-N, N, N', N'-Tetramethyluronium-Hexafluorophosphate;O-(1H-Benzotriazol-1-yl)-N, N, N', N'-Tetramethyluronium Hexafluorophosphate;2-(1H-Benzotriazole-1-yl)-1,1,3,3-Tetramethyluronium Hexafluorophosphate
Tshuag xwm txheej Hauv Tshuag, Kev Lag Luam Loj
CAS Nr 94790-37-1 ib
Molecular Formula C11H16F6N5 PAB
Molecular Luj 379.25 g / mol
Melting Point ≥200 ℃
Qhov ntom 1.509 5
rhiab heev Lub teeb Sensitive, Moisture Sensitive
Dej Solubility Xyaum Insoluble hauv dej
Solubility Soluble hauv Acetonitrile.Me ntsis Soluble hauv Acetone, Ethanol
Cia Temp. Qhov chaw txias & qhuav (2 ~ 8 ℃)
COA & MSDS Muaj
Qeb Coupling Reagents
Hom Ruifu Tshuaj

Specifications:

Cov khoom Kev soj ntsuam Standards Cov txiaj ntsig
Qhov tshwm sim Dawb Crystalline hmoov Ua raws
Melting Point ≥200 ℃ 205.6 ℃
Poob rau ziab <0.50% 0.11%
Purity / Analysis Method > 99.0% (HPLC) 99.9%
Infrared Spectrum Raws li tus qauv Ua raws
NMR Spectrum 1H Raws li tus qauv Ua raws
Fluorine NMR Spectrum Raws li tus qauv Ua raws
Solubility Test hauv Acetonitrile 1g hauv 10ml Acetonitrile Clear Solution Hla
Xaus Cov khoom tau raug kuaj & ua raws li cov specifications

Pob / Cia /Kev xa khoom:

Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov txias thiab qhuav (2 ~ 8 ℃) warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.

HBTU Test Method:

1. Khoom: Cov khoom no yuav tsum yog cov hmoov dawb crystalline hmoov.
2. Kev txiav txim siab txog cov ntsiab lus: raws li kev ua haujlwm siab ua kua chromatography (Suav Pharmacopoeia 2010 tsab Appendix VI D) kev txiav txim.
Chromatographic tej yam kev mob: Lub octadecylsilane bonded silica gel tau siv los ua muab tub lim, (250 * 4.6mm * 5.0μm);Acetonitrile: dej = 15:85 (pH kho los ntawm acetic acid = 2.5) raws li theem mobile;Kev kuaj pom wavelength yog 258nm.Tus nqi ntws: 0.5ml / min;Tus naj npawb ntawm cov phiaj xwm theoretical raws li HBTU
Qhov siab tshaj plaws yuav tsum suav tsis pub tsawg tshaj 2000.
Kev txiav txim siab txoj kev: Siv cov khoom tsim nyog ntawm cov khoom no, ua rau lub xov tooj ntawm tes uas muaj HBTU 20μg ib 1ml, raws li cov tshuaj ntsuam xyuas.10 μL ntawm cov tshuaj ntsuam xyuas tau txhaj rau hauv chromatograph thiab ob zaug ntawm lub sijhawm khaws cia ntawm lub ntsiab lus tseem ceeb ntawm lub ncov tau sau tseg.
Cov txiaj ntsig: Raws li txoj hauv kev normalization ntawm cheeb tsam, HBTU cov ntsiab lus yuav tsum tsis pub tsawg dua 99.0%.
3. Melting point: raws li txoj kev txiav txim siab melting point (Appendix VIIC of Chinese Pharmacopoeia 2010 edition), cov cua kub yog 3 ℃ / min.
Lub melting point ntawm cov khoom no tsis tsawg tshaj li 200.0 ℃.
4. Poob ntawm kev ziab: nqa cov khoom no mus rau 80 ℃ thiab qhuav hauv qhov txo qis rau 4 teev kom qhov hnyav tas li, thiab qhov hnyav poob yuav tsum tsis pub tshaj 0.50%.
5. Qhov tseeb ntawm cov tshuaj: noj 1g ntawm cov khoom no, ntxiv 10ml ntawm acetonitrile, co zoo, cov tshuaj yuav tsum tau meej thiab pob tshab.
6. Cia: Khaws rau hauv qhov chaw tsaus thiab txias qhuav (2 ~ 8 ℃).
7. Lub sijhawm tshuaj xyuas: ib xyoos.

Qhov zoo:

Muaj peev xwm txaus: Muaj cov chaw txaus thiab cov kws tshaj lij

Kev Pabcuam Kev Ua Haujlwm: Ib qho kev pabcuam kev yuav khoom

Pob OEM: Kev cai pob thiab daim ntawv lo muaj

Kev xa khoom sai: Yog tias nyob hauv Tshuag, peb hnub xa khoom lav

Stable Supply: Khaws cov khoom tsim nyog

Kev them nyiaj yug Technical: Technology tov muaj

Kev Pabcuam Synthesis: Ntau yam ntawm grams mus rau kilos

High Quality: Tsim kom muaj kev ruaj ntseg zoo

FAQ:

Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.

Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.

Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.

ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.

Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.

Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.

MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.

Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.

Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.

Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.

Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.

Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.

94790-37-1 - Kev pheej hmoo thiab kev nyab xeeb:

Risk Codes
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R20/21/22 - Ua phem los ntawm kev nqus pa, tiv tauj nrog daim tawv nqaij thiab yog tias nqos.
R42/43 - Tej zaum yuav ua rau rhiab heev los ntawm kev nqus pa thiab sib cuag ntawm daim tawv nqaij.
Kev nyab xeeb piav qhia
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S36 - Hnav khaub ncaws tiv thaiv zoo.
S22 - Tsis txhob nqus plua plav.
WGK Germany 3
FLUKA BRAND F CODE 8-10-21
HS Code 2933990099
Hazard Note Irritant
Toxicity LD50 qhov ncauj hauv Luav:> 2000 mg / kg

Daim ntawv thov:

HBTU (CAS: 94790-37-1) yog ib qho kev sib txuas reagent siv hauv peptide synthesis.HBTU tau pom tias muaj txiaj ntsig zoo rau kev tshem tawm racemization.
HBTU yog ib qho kev sib txuas reagent feem ntau siv hauv cov khoom theem peptide synthesis.HBTU kuj tau siv rau hauv tus qauv Fmoc-based solid-phase peptide synthesis (SPPS) raws tu qauv.
HBTU, tom qab tau tshaj tawm hauv xyoo 1978, HBTU tus neeg sawv cev qhia tau hais tias muaj koob npe hauv chemistry thiab kev lag luam siv vim nws cov khoom ua kom me me.Ntxiv mus, nws kuj qhia tau hais tias tsis kam tawm tsam racemization.Tsis tshua muaj siab rau racemization yog ib qho tseem ceeb ntawm peptide synthesis.tshwj xeeb tshaj yog rau cov theem peptide synthesis, ntau yields nrog luv luv cov tshuaj tiv thaiv lub sij hawm yog ib qho tseem ceeb nyob rau hauv thiaj li yuav ua rau cov synthesis ntawm loj peptides ua tau.
Cov kev tshawb fawb tsis ntev los no qhia tau hais tias siv lead ua thiab cov qauv kev daws teeb meem ntawm tus neeg sawv cev sib txuas no yog guanidinium N-oxide thiab tsis yog uronium compound;Coupling reagent rau peptide synthesis;Qhov zoo yog: racemization tsawg heev, cov tshuaj tiv thaiv yooj yim, lub sijhawm luv luv, thiab cov txiaj ntsig siab.
Peptide synthesis vam khom feem ntau ntawm kev sib txuas ua haujlwm zoo thiab nyab xeeb.HBTU tau ua pov thawj los hloov cov carboxylic acids rau hauv azides zoo thiab siv tau.Cov txheej txheem yuav siv tau rau ntau yam carboxylic acids nrog rau n-tiv thaiv amino acids.Tsis tas li ntawd, HBTU yog qhov muaj txiaj ntsig zoo hauv ib lub lauj kaub sib xyaw ntawm dipeptidyl urea esters, ureas, thiab carbamates los ntawm cov kua qaub.Qhov zoo ntawm HBTU suav nrog cov ntsiab lus hauv qab no: 1) tsis tawg thiab yog li tsim nyog rau kev daws teeb meem / cov khoom siv theem peptide synthesis.2) siab solubility thiab stability nyob rau hauv classical kuab tshuaj.3) ua tau rau kev tshuaj xyuas cov tshuaj tiv thaiv colorimetric.

Sau koj cov lus ntawm no thiab xa tuaj rau peb