Histrelin Acetate CAS 76712-82-8 Peptide Purity (HPLC) ≥98.0% Hoobkas
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm Histrelin Acetate (CAS: 76712-82-8) nrog cov khoom zoo.Ruifu Chemical muab cov khoom ntawm GMP peptides.Ruifu tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav Histrelin Acetate,Please contact: alvin@ruifuchem.com
| Tshuaj npe | Histrelin Acetate |
| Synonyms | Histrelin;Histrelin acetic acid ntsev;Hom tshuaj npe Supprelin (Roberts Pharmaceutical);[des-Gly 10, D-His(Bzl) 6]-LH-RH Ethylamide;5-oxo-L-Prolyl-L-Histidyl-L-Tryptophyl-Lseryl-L-Tyrosyl-Nt-Benzyl-D-Histidyl-L-Leucyl-L-Arginyl-N-Ethyl-L-Prolinamide Diacetate |
| Peptide Sequence | Pyr-His-Trp-Ser-Tyr-D-His (Bzl)-Leu-Arg-Pro-NHEt Acetate ntsev |
| Daim ntawv ntsev | Acetate |
| Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Loj |
| CAS Nr | 76712-82-8 |
| Molecular Formula | C66H86N18O12 |
| Molecular Luj | 1323.52 g / mol |
| Qhov ntom | 1.46 ± 0.10g / cm3 |
| rhiab heev | Hygroscopic.Moisture Sensitive |
| Cia Temp. | Qhov chaw txias & qhuav (2 ~ 8 ℃).Lub tub yees |
| COA & MSDS | Muaj |
| Qeb | GMP Peptides |
| Txee lub neej | 24 lub hlis txij hnub tsim khoom yog tias khaws cia kom raug |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb Lyophilized Hmoov | Ua raws |
| Solubility | Soluble nyob rau hauv dej los yog 1% Acetic Acid ntawm ib tug Concentration ntawm ≥1mg / ml los muab ib tug ntshiab xim tsis tov tshuaj | Ua raws |
| MS | Monoisotopic pawg: 1323 ± 1.0 | 13 23.1 |
| Identity HPLC | Ib yam nrog rau Kev Siv Tshuaj | Ua raws |
|
Amino Acid Analysis | Ser: Present | Ua raws |
| Qhov hnyav: 0.85 ~ 1.1 | 0.95 ib | |
| Pro: 0.85 ~ 1.1 | 1.05 Nws | |
| Loj: 0.85 ~ 1.1 | 1.01 Nws | |
| Loj: 0.85 ~ 1.1 | 1.00 Nws | |
| Nws: 1.70 ~ 2.2 | 0.99 ib | |
| Qhov siab: 0.85 ~ 1.1 | 0.98 ib | |
| Trp: Tam sim no | Kev txiav txim | |
| Peptide Purity (HPLC) | ≥98.0% | 99.58% |
| Yam khoom (HPLC) | Tag nrho impurities (%) ≤2.0% | 0.42% |
| Lwm yam impurity ≤1.0% | 0.24% | |
| Cov ntsiab lus Acetate (HPLC) | ≤ 12.0% | 11.5% |
| Cov ntsiab lus dej (Karl Fischer) | ≤ 5.0% | 1.0% |
| Assay | 95.0 ~ 105.0% (Anhydrous, Acetic Acid Dawb) | 98.5% |
| Keeb kwm ntawm cov khoom | Synthetic | |
| Nco ntsoov | Tsuas yog rau Kev Tshawb Fawb, Tsis yog siv rau tib neeg | |
| Xaus | Cov khoom tau raug kuaj & ua raws li cov specifications | |
Pob:Yas vial (dawb rau peptide packing) los yog iav vial, kom muaj nuj nqis raws li tus neeg siv khoom xav tau.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov txias thiab qhuav (2 ~ 8 ℃) warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Hazard Symbols T - Toxic
Risk Codes
60 - Tej zaum yuav cuam tshuam fertility
Kev nyab xeeb piav qhia
S53 - Tsis txhob raug - tau txais cov lus qhia tshwj xeeb ua ntej siv.
S22 - Tsis txhob nqus plua plav.
S36/37/39 - Hnav cov khaub ncaws tiv thaiv, hnab looj tes thiab tiv thaiv qhov muag / ntsej muag.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg los tau.)
WGK Germany 3
TIAB SA 6370800
Histrelin Acetate (CAS: 76712-82-8), hluavtaws gonadotrophin-releasing hormone (GnRH) agonist, tau qhia ua thawj kab kev kho mob rau kev kho mob ntawm lub hauv paus precocious puberty.Thaum muab tshuaj rau lub sijhawm ntev, nws inhibits kev tso tawm ntawm gonadotrophin, inhibits zes qe menyuam thiab testicular steroidogenesis, thiab tiv thaiv kev sib deev maturation.Superior rau cov kev kho mob ib txwm muaj nrog cov tshuaj progestational, histrelin zoo nkaus li muaj kev cuam tshuam ntawm cov pob txha loj hlob uas tso cai rau kev loj hlob ntau dua thiab ua rau cov neeg laus qhov siab kawg.Histrelin kuj tau siv los kho lwm yam kab mob xws li endometriosis, polycystic zes qe menyuam kab mob, uterine leiomyomas, mob hnyav premenstrual syndrome thiab tiv thaiv mob porphyria mob.
Lus Txhais: Ib qho oligopeptide suav nrog pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, 1-benzyl-D-histidyl, leucyl, arginyl, thiab N-ethylprolinamide residues koom ua ke.Nws yog ib qho hluavtaws nonapeptide analogue ntawm gonadotro hauv-tso cov tshuaj hormones, thiab yog siv los ua subcutaneous hydrogel implant (tshwj xeeb yog cov ntsev diacetate) rau kev kho mob qog noj ntshav prostate thiab rau kev tawm tsam ntawm gonadal txiv neej pw cov tshuaj hormones hauv cov menyuam yaus nrog lub hauv paus precocious puberty.Siv rau precocious puberty.
Biochem/Physiol Actions: Histrelin Acetate yog GnRH (gonadotropin-tso hormone) agonist, histerelin.GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), uas tseem hu ua LHRH (luteinizing hormone-releasing hormone) los yog gonadorelin, yog qhov tseem ceeb rau cov tsiaj yug me nyuam thiab tso tawm los ntawm hypothalamic neurons.Nws yog lub luag haujlwm rau kev tso tawm ntawm gonadotropins, luteinizing hormone (LH) thiab follicle-stimulating hormone (FSH), los ntawm cov qog pituitary.Kev hloov pauv hauv GnRH muaj feem cuam tshuam nrog rau qhov normosmic congenital hypogonadotropic hypogonadism.Histerelin yog siv rau kev kho mob ntawm central precocious puberty nyob rau hauv cov me nyuam.Nws inhibits kev ua ntawm kev sib deev steroids ntawm tus txiv neej thiab poj niam lub cev xeeb tub.
Nws muaj raws li kev txhaj tshuaj intramuscular txhua hnub.Histrelin tseem muaj nyob rau hauv 12-hli subcutaneous implant (Vantas) rau palliative kev kho mob ntawm prostate mob cancer siab heev (txij li thaum 2005 nyob rau hauv Teb Chaws Asmeskas, thiab txij li thaum Lub ib hlis ntuj 2010 nyob rau hauv UK. Puberty (CPP) tau pom zoo rau lub Tsib Hlis 3, 2007 los ntawm US Food and Drug Administration.
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