HOBt Anhydrous CAS 2592-95-2 1-Hydroxybenzotriazole Anhydrous Peptide Coupling Reagent Purity > 99.0% (HPLC) Hoobkas
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom ntawm 1-Hydroxybenzotriazole Anhydrous (HOBt Anhydrous) (CAS: 2592-95-2) nrog cov khoom zoo.Ruifu Chemical muab cov txheej txheem tiv thaiv reagents thiab coupling reagents.Ruifu tuaj yeem muab kev xa khoom thoob ntiaj teb, tus nqi sib tw, me me thiab ntau ntau muaj.Yuav HOBt Anhydrous,Please contact: alvin@ruifuchem.com
Tshuaj npe | 1-Hydroxybenzotriazole Anhydrous |
Synonyms | HOBt Anhydrous;HOBt;1-Hydroxybenzotriazole;N-Hydroxybenzotrizole;1-Hydroxy-1H-Benzotriazole;1-Benzotriazolol;1-Hydroxy-1,2,3-Benzotriazole |
Tshuag xwm txheej | Hauv Tshuag, Kev Lag Luam Loj |
CAS Nr | 2592-95-2 |
Molecular Formula | C6H5N3O |
Molecular Luj | 135.1 g / mol |
Melting Point | 156.0 ~ 162.0 ℃ |
Qhov ntom | 1 g/cm3 |
Refractive Index n20/D | 1.488 ib |
rhiab heev | Lub teeb Sensitive |
Solubility hauv Methanol | Soluble nyob rau hauv Methanol, Yuav luag Transparency |
Kev ruaj ntseg | Stable, Tab sis muaj peev xwm txaus ntshai ntawm tawg yog Heated nyob rau hauv kaw.Flamable. |
Cia Temp. | Qhov chaw txias & qhuav (≤4 ℃) |
COA & MSDS | Muaj |
Qeb | Coupling Reagents |
Hom | Ruifu Tshuaj |
Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov | Ua raws |
Melting Point | 156.0 ~ 162.0 ℃ | 158.7 ~ 159.5 ℃ |
Dej los ntawm Karl Fischer | <0.50% | 0.24% |
Heavy Metals (Pb) | ≤ 20ppm | <20 ppm |
Purity / Analysis Method | > 99.0% (HPLC) | 99.90% |
300 MHz 1HNMR Spectrum | Raws li tus qauv | Ua raws |
Infrared Spectrum | Raws li tus qauv | Ua raws |
Xaus | Cov khoom tau raug kuaj & ua raws li cov lus qhia tshwj xeeb |
Pob:Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov txias thiab qhuav (≤4 ℃) warehouse kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Shipping:Xa mus thoob ntiaj teb los ntawm FedEx / DHL Express.Muab kev xa khoom sai thiab txhim khu kev qha.
1. Khoom: Cov khoom no yuav tsum yog dawb mus rau dawb crystalline hmoov.
2. Kev txiav txim siab txog cov ntsiab lus: raws li kev ua haujlwm siab ua kua chromatography (Suav Pharmacopoeia 2010 tsab ntawv ntxiv VI D) kev txiav txim siab
Chromatographic tej yam kev mob: Lub octadecylsilane bonded silica gel tau siv los ua muab tub lim, (250 * 4.6mm * 5.0μm);Nrog Acetonitrile: Dej (Ph = 2.5 trifluoroacetic acid aqueous tov) = 50:50 yog theem mobile;Kev kuaj pom wavelength yog 258nm.Tus nqi ntws: 0.5ml / min;Tus naj npawb ntawm cov phiaj xwm theoretical yuav tsum tsis pub tsawg dua 2000 raws li qhov tseem ceeb ntawm HOBt.
Txoj kev txiav txim siab: Noj cov khoom no, ua cov tshuaj acetonitrile uas muaj HOBt 20μg hauv txhua 1ml, raws li cov khoom siv tshuaj ntsuam xyuas kua.10μl ntawm cov tshuaj ntsuam xyuas tau txhaj rau hauv chromatograph, thiab chromatogram tau sau tseg rau 2 zaug ntawm lub sijhawm tuav ntawm lub ntsiab lus tseem ceeb.
Cov txiaj ntsig: HOBt tsis tsawg dua 99.0% los ntawm txoj kev normalization hauv cheeb tsam.
3. Melting point: raws li tus txheej txheem ntawm melting point kev txiav txim (Suav Pharmacopoeia 2010 tsab Appendix VIIC) txiav txim raws li txoj cai.
Lub melting point ntawm cov khoom no yuav tsum yog 156.0 ~ 162.0 ℃.
4. Kev ntsuas dej cov ntsiab lus: raws li kev ntsuas dej noo (KF txoj kev) los txiav txim siab cov ntsiab lus dej ntawm cov khoom yuav tsum tsawg dua 0.5%.
5. Cia: Khaws rau hauv qhov chaw txias thiab qhuav kom deb ntawm lub teeb.
6. Reinspection lub sij hawm: ib xyoos
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
Risk Codes
R11 - Cov nplaim hluav taws kub heev
R5 - Cua sov tuaj yeem ua rau tawg
R36/38 - Kab mob rau qhov muag thiab tawv nqaij.
R36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij.
R36 - Khau qhov muag
R20/21 - Ua phem los ntawm kev nqus pa thiab sib cuag nrog daim tawv nqaij.
R61 - Tej zaum yuav ua rau muaj mob rau tus menyuam hauv plab
R2 - Kev pheej hmoo ntawm kev tawg los ntawm kev poob siab, kev sib txhuam, hluav taws kub lossis lwm yam khoom siv hluav taws xob
Kev nyab xeeb piav qhia
S16 - Khaws kom deb ntawm qhov chaw hluav taws xob.
S33 - Siv cov kev tiv thaiv kev tiv thaiv zoo li qub.
S7/9 -
S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob.
S45 - Thaum muaj xwm txheej lossis yog tias koj tsis xis nyob, nrhiav kev kho mob tam sim ntawd (qhia daim ntawv lo thaum twg los tau.)
S53 - Tsis txhob raug - tau txais cov lus qhia tshwj xeeb ua ntej siv.
S15 - Cia kom deb ntawm tshav kub.
S36/37 - Hnav cov khaub ncaws tiv thaiv thiab hnab looj tes tsim nyog.
S35 - Cov khoom no thiab nws lub thawv yuav tsum muab pov tseg rau hauv txoj kev nyab xeeb.
UN IDs 1325
RTECS DM1288000
HS Code 2933990099
Hazard Chav Kawm 4.1
Packing Group III
1-Hydroxybenzotriazole Anhydrous (HOBt Anhydrous) (CAS: 2592-95-2), additives rau oligonucleotide couplings thiab nyob rau hauv racemization-dawb peptide couplings.HOBt, raws li kev lag luam khoom lag luam, nws yog tsuas yog siv los txo cov racemization ntawm ib leeg-enantiomerchiral molecules thiab txhim kho kev ua haujlwm ntawm peptide synthesis.automated peptide synthesisinvolves lub condensation ntawm cov amino pawg tiv thaiv amino acids nrog lub tshuab txais ester.HOBt tuaj yeem siv los tsim cov activated esters xws li n-hydroxysuccinimide ester.Cov esters no yog insoluble thiab hnov mob nrog amines ntawm ambient kub los muab amides.HOBt kuj tseem siv rau kev sib txuas ntawm amides los ntawm carboxylic acidsaside los ntawm cov amino acids.Cov substrates no yuav tsis hloov mus rau theacyl chlorides.Piv txwv li, amide derivatives ntawm ionophoric tshuaj tua kab mob tau npaj nyob rau hauv txoj kev no.
Siv ua ib qho nruab nrab hauv cov organic synthesis.Siv raws li nruab nrab hauv kev sib txuas ntawm ubenamex, polypeptide tiv thaiv tus neeg sawv cev.Siv ua ib qho nruab nrab hauv cov organic synthesis.
Amino Acids thiab Peptide Synthesis Reagents;Condensing Agents;Additives rau Condensation Reactions.