Ibrutinib CAS 936563-96-1 Purity > 99.5% (HPLC) API

Lus piav qhia luv luv:

Lub npe tshuaj: Ibrutinib

CAS: 936563-96-1 Nr

Purity:> 99.5% (HPLC)

Cov tsos mob: Dawb rau Off-White Crystal Powder

Ibrutinib yog BTK inhibitor siv los kho cov kab mob Lymphocytic Leukemia (CLL) thiab Mantle Cell Lymphoma (MCL)

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Xa email rau peb

Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Chemical Properties:

Tshuaj npe	Ibrutinib
Synonyms	1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1- ib;PCI-32765
CAS Nr	936563-96-1
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C25H24N6O2
Molecular Luj	440.50 Nws
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Crystal Powder
Kev txheeb xyuas	IR;HPLC
Poob rau ziab	<0.50%
Residue ntawm Ignition	≤0.10%
Heavy Metals (raws li Pb)	≤ 20ppm
Ib qho Impurity	≤ 0.20%
Tag nrho cov impurities	<0.50%
Purity / Analysis Method	> 99.5% (HPLC)
Test Standard	Enterprise Standard
Kev siv	API

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.

Qhov zoo:

FAQ:

Daim ntawv thov:

Ibrutinib (CAS: 936563-96-1) yog ib qho inhibitor ntawm Bruton tyrosine kinase (BTK) rau kev kho mob ntawm chronic lymphocytic leukemia (CLL) thiab mantle cell lymphoma (MCL).Ob leeg MCL thiab CLL belongs rau B-cell non-Hodgkin's lymphoma, uas yog refractory thiab nquag rov qab.Kev siv tshuaj chemoimmunotherapy feem ntau tsis yog lub hom phiaj, thiab qib 3 lossis 4 cov kev phiv tshwm sim feem ntau tshwm sim.Ibrutinib tuaj yeem ua ke nrog BTK, uas yog tsim nyog rau kev tsim, sib txawv, kev sib txuas lus thiab kev ciaj sia ntawm B lymphocytes, thiab irreversibly inhibit qhov kev ua ntawm BTK, zoo inhibit qhov kev loj hlob thiab ciaj sia ntawm cov qog hlwb.Tsis tas li ntawd, nws tau nqus sai sai tom qab kev tswj hwm qhov ncauj, qhov siab tshaj plaws ntawm plasma concentration yog mus txog 1 ~ 2h, thiab cov kev cuam tshuam tsis zoo yog qib 1 lossis 2, uas yuav dhau los ua qhov kev xaiv tshiab rau kev kho mob ntawm CLL thiab MCL.Thaum Lub Kaum Ib Hlis 13, 2013, US FDA txhawm rau txhawm rau pom zoo Johnson & Johnson lub tuam txhab thiab Tebchaws Asmeskas Imbruvica (ib lub npe: Ibrutinib) rau kev kho mob ntawm mantle cell lymphoma (MCL).Ibrutinib, tau txais txiaj ntsig los ntawm Kev Kho Mob los ntawm FDA thaum Lub Ob Hlis 2013 thiab tau pom zoo rau MCL thaum Lub Kaum Ib Hlis 13, 2013 thiab CLL rau Lub Ob Hlis 12, 2014, raws li.