Ibrutinib Deacryloylpiperidine CAS 330786-24-8 Purity > 99.0% (HPLC)

Lus piav qhia luv luv:

Lub npe tshuaj: Ibrutinib Deacryloylpiperidine

CAS: 330786-24-8 Nr

Purity:> 99.0% (HPLC)

Cov tsos mob: Tawm-dawb rau Khaki hmoov

Intermediate of Ibrutinib (CAS: 936563-96-1)

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Xa email rau peb

Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Chemical Properties:

Tshuaj npe	3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Synonyms	Ibrutinib intermeidate N-2;Ibrutinib Deacryloylpiperidine;Ibrutinib impurity 8;5-(4-Phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine;IB 4A;Ibrutinib N-Despiperidinyl Impurity
CAS Nr	330786-24-8
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C17H13N5O
Molecular Luj	303.32 Nws
Melting Point	≥262 ℃ (txog.)
Qhov ntom	1.380 ± 0.06g / cm3
Hazard Class	6.1;Tshuaj lom
Packing Group	III
COA & MSDS	Muaj
Keeb kwm	Shanghai, Suav
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Off-White rau Khaki hmoov
Kev txheeb xyuas	HNMR, LC-MS
Purity / Analysis Method	> 99.0% (HPLC)
Poob rau ziab	<1.00%
Single Max.impurity	<1.00%
Tag nrho cov impurities	<1.00%
Heavy Metals (raws li Pb)	<20 ppm
Test Standard	Enterprise Standard
Kev siv	Intermediate of Ibrutinib (CAS: 936563-96-1)

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.

Qhov zoo:

FAQ:

330786-24-8 - Daim ntawv thov:

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS: 330786-24-8) yog ib qho tseem ceeb hluavtaws intermediate hauv cov synthesis ntawm Ibrutinib (CAS: 936563-96-1) ).Ibrutinib yog ib hom Bruton tyrosine kinase (BTK) inhibitor, nws tuaj yeem siv rau kev kho mob ntawm cov qog ntshav qog ntshav qog ntshav (CLL) thiab mantle cell lymphoma (MCL).MCL thiab CLL yog koom nrog B-cell non-Hodgkin's lymphoma, uas nyuaj rau kho thiab yooj yim rau rov tshwm sim.Hom tshuaj tiv thaiv kab mob tsis muaj lub hom phiaj, feem ntau tshwm sim 3 lossis 4 qhov tsis zoo tshwm sim.Ibrutinib thiab B lymphocytes tuaj yeem tsom nrog BTK uas yog qhov tsim nyog rau kev tsim, sib txawv, thiab xa cov ntaub ntawv, inhibit BTK kev ua haujlwm tsis zoo, thiab inhibit qog cell proliferation thiab ciaj sia taus.Ibrutinib tuaj yeem nqus tau sai sai tom qab kev tswj hwm qhov ncauj, thaum lub sijhawm 1 ~ 2h mus txog qhov siab tshaj plaws ntawm cov ntshav, cov kev cuam tshuam tsis zoo rau ib lossis ob, yog li ntawd, Ibrutinib yuav dhau los ua kev xaiv tshiab ntawm kev kho mob CLL thiab MCL.