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N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity Featured duab
  • N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS 152460-09-8 Imatinib Mesylate Intermediate High Purity

Lus piav qhia luv luv:

N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine

CAS: 152460-09-8 Nr

Cov tsos mob: daj los yog yuav luag daj hmoov

Purity: ≥98.0% (HPLC)

Intermediate ntawm Imatinib Mesylate (CAS: 220127-57-1) hauv kev kho mob Philadelphia Chromosome-Positive Chronic Myeloid Leukemia (Ph + CML)

High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com


Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Kev muag khoom lag luam Imatinib Mesylate thiab Cov Khoom Sib Txuas Txuas:
Imatinib Mesylate CAS NO: 220127-57-1
N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine CAS: 152460-09-8
N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidinea CAS: 152460-10-1
4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride CAS: 106261-49-8

Chemical Properties:

Tshuaj npe N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine
Synonyms Imatinib Mesylate Intermediate;2-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine
CAS Nr 152460-09-8
CAT Number Qauv: RF-PI228
Tshuag xwm txheej Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula C16H13N5O2
Molecular Luj 307.31 Nws
Melting Point 188.0 ~ 193.0 ℃
Hom Ruifu Tshuaj

Specifications:

Yam khoom Specifications
Qhov tshwm sim Yellow los yog Yellow Powder
Purity ≥98.0% (HPLC)
Moisture (KF) ≤0.50%
Tag nrho cov impurities ≤ 2.0%
Qhov siab tshaj plaws ib leeg impurity ≤ 1.0%
Residue ntawm ignition ≤0.50%
Hnyav Hlau ≤ 20ppm
Test Standard Enterprise Standard
Kev siv Intermediate ntawm Imatinib Mesylate (CAS: 220127-57-1)

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.

Qhov zoo:

1

FAQ:

Daim ntawv thov:

Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab chaw muag khoom ntawm N-(2-Methyl-5-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine (CAS: 152460-09-8) nrog siab zoo.Nws yog ib qho nruab nrab feem ntau hauv kev sib txuas ntawm Imatinib Mesylate (CAS: 220127-57-1).
Imatinib Mesylate yog ib qho me me molecule uas inhibits c-Abl protein-tyrosine kinase, tshwj xeeb tshaj yog rau BCR-ABL, cov enzyme txuam nrog mob myelogenous leukemia (CML) thiab qee hom mob lymphoblastic leukemia (ALL).Ib qho kev hloov pauv ntawm chromosomes 9 thiab 22 ua rau Philadelphia chromosome, uas tom qab ntawd ua rau Bcr-Abl fusion protein nrog aberrant kinase kev ua haujlwm uas txhawb nqa kev loj hlob sai ntawm tes.Imatinib Mesylate khi rau qhov tseem ceeb kinase, txwv tsis pub CML ntsig txog kev loj hlob.Imatinib Mesylate tau nthuav tawm ntxiv los inhibit PDGFR thiab tyrosine kinases cuam tshuam nrog c-Kit.Cov tshuaj uas muaj Imatinib Mesylate tau siv los kho ntau yam qog noj ntshav.

Sau koj cov lus ntawm no thiab xa tuaj rau peb