Indapamide CAS 26807-65-8 Purity ≥99.5% (HPLC) API EP Standard Hoobkas High Quality
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Indapamide thiab lwm yam intermediates nrog cov khoom zoo.
Indapamide CAS 26807-65-8
2-Methylindoline CAS 6872-06-6
1-Amino-2-Methylindoline Hydrochloride CAS 102789-79-7
| Tshuaj npe | Indapamide |
| Synonyms | N-(4-Chloro-3-Sulfamoylbenzamido)-2-Methylindoline |
| CAS Nr | 26807-65-8 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C16H16ClN3O3S |
| Molecular Luj | 365.83 ib |
| Melting Point | 160.0 ~ 162.0 ℃ |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb los yog Yuav luag Dawb Crystalline Hmoov |
| Solubility | Xyaum Insoluble hauv dej;Soluble hauv Ethanol |
| Kev Taw Qhia A | Ultraviolet thiab Visible Absorption Spectrophotometry |
| Kev Qhia B | Infrared Absorption Spectrophotometer |
| Kev txheeb xyuas C | Nyias-txheej Chromatography |
| Kev hloov kho qhov muag | -0.80 ° ~ + 0.80 ° (C = 5, C2H5OH) |
| Dej (EP 2.5.12) | <3.00% |
| Sulfated tshauv (EP 2.4.14) | <0.10% |
| Heavy Hlau (EP 2.4.8) | <10ppm |
| Yam khoom muaj feem | |
| Impurity B | <0.30% |
| Unspecified impurity | <0.10% |
| Tag nrho cov impurities | <0.50% |
| Purity / Analysis Method | > 99.5% (HPLC) |
| Test Standard | EP Txheem |
| Kev siv | API;Antihypertensive thiab Diuretic |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
Indapamide (CAS: 26807-65-8) yog ib qho tshuaj tiv thaiv kab mob siab thiab diuretic.Los ntawm inhibiting Na + reabsorption ntawm qhov kawg ntawm qhov kawg ntawm distal conflexion tubules, nws ua rau cov nyhuv diuretic thiab tseem thaiv Ca2 + influx.Nws muaj kev xaiv siab rau vascular du nqaij, dilates peripheral me hlab ntsha thiab ua rau cov nyhuv hypotensive.Tab sis cov nyhuv ntawm vascular du cov leeg muaj zog diuretic nyhuv, hauv qab cov tshuaj diuretic tuaj yeem txo qis, cov koob tshuaj ntau dua pom cov nyhuv diuretic, tab sis tsis muaj thiazide diuretic shortcomings, uas yog tsis ua rau orthostatic hypotension, flush thiab reflective tachycardia, ntawm cov ntshav duab, metabolism hauv cov ntshav. rog, qab zib thiab lub raum ua haujlwm kuj tsis muaj qhov pom tseeb, kev kho mob ntawm lub plawv dhia, lub plawv tso zis, tsis muaj kev hloov pauv tseem ceeb hauv electrocardiogram (ecg) yog Nws tsis muaj kev cuam tshuam rau lub hauv nruab nrab lub paj hlwb thiab lub paj hlwb autonomic.Kev tswj qhov ncauj ntawm 2 ~ 3 chemicalbook H ua rau cov nyhuv hypotensive, uas tau khaws cia rau 24 teev.Diuretic nyhuv tshwm sim ntawm 3h thiab mus txog nws qhov siab tshaj plaws ntawm 4 ~ 6h.Indapamide yog qhov tsim nyog rau cov ntshav siab me me thiab nruab nrab, kuj tuaj yeem siv rau kev mob plawv tsis ua haujlwm los ntawm dej sodium tuav, nrog rau lub raum tsis ua haujlwm kuj tseem siv tau rau cov neeg mob ntshav siab, ntshav qab zib, hyperlipidemia, siv cov nyhuv antihypertensive zoo kawg li.
