Inosine CAS 58-63-9 Assay 98.0 ~ 102.0% Hoobkas Zoo
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Inosine (CAS: 58-63-9) nrog cov khoom zoo, ua tau raws li tus qauv ntawm Suav Pharmacopoeia ChP2020 II.Peb cov khoom yog muag rau Asmeskas thiab Europe, Is Nrias teb, thiab cov tuam txhab tshuaj muaj npe nrov hauv Suav teb.Cov khoom tau txais lub koob npe nrov hauv kev lag luam thoob ntiaj teb thiab hauv tsev.Peb tuaj yeem muab kev xa khoom thoob ntiaj teb, me me thiab ntau qhov ntau.Yog tias koj txaus siab rau Inosine (CAS: 58-63-9),Please contact: alvin@ruifuchem.com
Tshuaj npe | Inosine |
Synonyms | (-)-Inosine;Hypoxanthine 9-β-D-Ribofuranoside;Hypoxanthine-9-beta-D-Ribofuranoside;Atorel;beta-Inosine;Hypoxanthine D-Riboside;1,9-Dihydro-9-β-D-Ribofuranosyl-6H-purin-6-ib;Hypoxanthine Riboside;Hypoxanthine Ribonucleoside;9-β-D-Ribofuranosylhypoxanthine |
Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 30 Tons ib Hlis |
CAS Nr | 58-63-9 |
Molecular Formula | C10H12N4O5 |
Molecular Luj | 268.23 ib |
Melting Point | 222.0 ~ 226.0 ℃ (dec.) (lit.) |
rhiab heev | Hygroscopic |
Solubility | Me ntsis Soluble hauv dej, Insoluble hauv Ethanol, thiab Soluble hauv Dilute Hydrochloric Acid thiab Sodium Hydroxide Solution. |
tsw | Tsis hnov tsw |
Cia Temp. | Muab ntim rau hauv Qhuav, Khaws ntawm Chav Kub |
COA & MSDS | Muaj |
Hom | Ruifu Tshuaj |
Hazard Codes | Xis - Irritant | RTECS | NM7460000 |
Risk Statements | 36/37/38 ib | F | 10 |
Cov lus hais txog kev nyab xeeb | 24/25-36-26 ib | TSCA | Yog lawm |
WGK Germany | 2 | HS Code | 2934993090 ib |
Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
Qhov tshwm sim | Dawb Crystals lossis Crystalline Hmoov;Tsis muaj ntxhiab tsw;Me ntsis iab saj | Ua raws |
Kev txheeb xyuas | 1) Qhia qhov zoo tshwm sim 2) Lub Sijhawm khaws cia ua raws li tus qauv 3) Infraned Absorption | Ua raws |
State of Solution (Kev xa tawm) | ≥98.0% | Ua raws |
Heavy Metals (Pb) | ≤10ppm | <10ppm |
Arsenic (As2O3) | ≤ 1.0ppm | <1.0ppm |
Poob rau ziab | ≤1.00% (ntawm 105 ℃ rau 3 teev) | 0.40% |
Residue ntawm Ignition (Sulfated) | ≤ 0.20% | 0.07% |
Yam khoom muaj feem | Tag nrho impurities nto thaj tsam max 1.0% ntawm qhov dav peek cheeb tsam | Ua raws |
Assay | 98.0 txog 102.0% | 99.4% |
Tus nqi pH | 4.8 txog 5.8 (1.0g hauv 100ml ntawm H2O) | 5.0 |
Kev ntsuam xyuas microbiological | ||
Tag nrho Aerobic txwv | ≤800CFU / g | 40 CFU/g |
Tag nrho Pwm txwv | ≤80 CFU / g | 10 CFU/g |
Poov xab | ≤80 CFU / g | 10 CFU/g |
Escherichia Coli | Tsis zoo | Tsis zoo |
Xaus | Ua tau raws li tus qauv ntawm ChP2020 II |
Inosine (CAS: 58-63-9) ChP2020 Test Method
Inosine - KEV NTSEEG
Cov ntsiab lus ntawm C10H12N4O5 yuav tsum nyob nruab nrab ntawm 98.0% thiab 102.0% xam ntawm cov khoom qhuav.
Inosine - Cim Cov khoom no yog dawb crystalline hmoov;Tsis hnov tsw.Cov khoom no yog me ntsis soluble hauv dej, insoluble hauv ethanol, thiab soluble hauv dilute hydrochloric acid thiab sodium hydroxide tov.
Inosine - IDENTIFICATION
1. Siv cov tshuaj 0.01% ntawm cov khoom no, ntxiv cov ntim sib npaug ntawm 3, 5-dihydroxytoluene tov ( noj 3, 5-dihydroxytoluene thiab ferric chloride 0.lg, ntxiv hydrochloric acid ua 100ml), sib tov zoo, tom qab ntawd cua sov hauv dej da dej li 10 feeb, pom xim ntsuab.
2. Nyob rau hauv chromatogram sau tseg nyob rau hauv cov ntsiab lus kev txiav txim cov khoom, lub sij hawm tuav ntawm lub ntsiab ncov ntawm cov tshuaj ntsuam xyuas yuav tsum tau raws li lub sij hawm tuav ntawm lub ntsiab ncov ntawm cov ntaub ntawv siv.
3. Lub infrared absorption spectrum ntawm cov khoom no yuav tsum ua raws li cov kev tswj hwm (Spectrum teeb 605).
Inosine - Kev tsom xam
Transmittance ntawm kev daws teeb meem
Noj 0.5g ntawm cov khoom no, ntxiv 50ml dej kom yaj, raws li UV-pom spectrophotometry (Txoj cai lij choj 0401), txiav txim siab qhov kev xa tawm ntawm 430nm wavelength, tsis tsawg dua 98.0%.(rau txhaj tshuaj)
Yam khoom muaj feem
Noj cov khoom no, ntxiv dej kom yaj thiab dilute los ua cov tshuaj uas muaj 0.5mg ib 1ml raws li kev sim tshuaj;Siv 1ml rau kev ntsuas qhov tseeb, muab tso rau hauv 100ml ntsuas lub khob, dilute nws nrog dej mus rau qhov ntsuas, raws li kev tswj kev daws teeb meem.Raws li cov xwm txheej chromatographic nyob rau hauv cov ntsiab lus kev txiav txim siab, 20 u1 ntawm kev ntsuas kev daws teeb meem thiab kev tswj kev daws teeb meem feem ntau raug txhaj rau hauv cov kua chromatograph, thiab chromatogram raug kaw rau 2 zaug ntawm lub sijhawm tuav ntawm lub ntsiab ncov.Yog hais tias muaj impurity peaks nyob rau hauv lub chromatogram ntawm cov tshuaj ntsuam xyuas, cov sum ntawm txhua impurity ncov cheeb tsam yuav tsum tsis txhob ntau tshaj lub ntsiab ncov cheeb tsam ntawm kev tswj cov tshuaj (1.0%).
Poob rau ziab
Noj cov khoom no, qhuav mus tas li qhov hnyav ntawm 105 ° C, qhov hnyav poob yuav tsum tsis pub tshaj 1.0% (Txoj cai 0831).
Residue ntawm Ignition (Sulfated)
Tsis ntau tshaj 0.1% (rau kev txhaj tshuaj), lossis tsis ntau tshaj 0.2% (rau kev siv qhov ncauj) (Txoj cai 0841).
Hnyav Hlau
Noj cov khoom no 1.0g, tshuaj xyuas raws li txoj cai (Cov Ntsiab Cai 0821 thib ob txoj cai), uas muaj cov hlau hnyav yuav tsum tsis pub tshaj 10 feem ntawm ib lab.
Mob toxicity
Noj cov khoom no, ntxiv cov tshuaj sodium chloride kom yaj thiab dilute cov tshuaj uas muaj inosine 10mg ib 1ml, xyuas raws li txoj cai (Txoj cai 1141), yuav tsum ua raws li cov kev cai.(rau txhaj tshuaj)
Inosine - Kev txiav txim siab txog cov ntsiab lus
Ntsuas los ntawm High Performance Liquid Chromatography (General 0512).
Chromatographic tej yam kev mob thiab system haum xeem silica gel bonded nrog kaum yim alkyl silane tau siv los ua tus muab tub lim;Methanol-dej (10:90) tau siv los ua lub sijhawm txawb;Kev kuaj pom wavelength yog 248nm.Noj li 10mg ntawm inosine siv, ntxiv 1 mol / L hydrochloric acid tov (1ml), tshav kub hauv dej da dej ntawm 80 ℃ rau 10 feeb, cia nws txias, ntxiv 1ml ntawm 1 mol / L sodium hydroxide tov, ntxiv dej rau 50ml, 20u1 txhaj tshuaj kua chromatograph, kho lub chromatographic system, kev sib cais degree ntawm inosine ncov thiab nyob ib sab impurity ncov yuav tsum tau raws li qhov yuav tsum tau, tus naj npawb ntawm theoretical phaj raws li inosine ncov xam tsis tsawg tshaj li 2000.
Assay
Siv cov khoom tsim nyog ntawm cov khoom no, ua kom raug hnyav, ntxiv dej kom yaj thiab ua kom muaj nuj nqis los ua cov tshuaj uas muaj li 20ug ib lml, co nws, thiab siv nws los ua cov tshuaj ntsuam xyuas, A 20ul txhaj tshuaj kua chromatograph raug ntsuas kom raug thiab cov chromatogram tau sau tseg.Tus nqi tsim nyog ntawm inosine siv tau raug ntsuas raug ntsuas thiab txiav txim siab los ntawm tib txoj kev, thiab thaj chaw ncov raug xam raws li tus qauv txheej txheem sab nraud.
Inosine - Qeb
Cell metabolism txhim kho cov tshuaj.
Inosine - Cia
Lub teeb shielding, kaw ruaj khov.
Pharmaceuticals: (1) Inosine Oral Solution (2) Inosine Tablets (3) Inosine Txhaj (4) Inosine Capsules (5) Inosine thiab Glucose Txhaj (6) Inosine thiab Sodium Chloride Txhaj (7) Inosine txhaj
Pob: Fluorinated Fwj, 25kg / hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias, qhuav thiab cua tshuab kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
1. Inosine (CAS: 58-63-9), raws li cov khoom siv nucleoside, feem ntau yog siv los tsim cov tshuaj rau kev kho mob ntawm cov kab mob thiab lwm yam kab mob.
2. Inosine yog ib qho non-canonical nucleotide feem ntau yog monophosphate.Nws muaj peev xwm los ua khub nrog deoxythymidine, deoxyadenosine thiab deoxyguanosine.Kev koom ua ke ntawm inosine nyob rau hauv qhov chaw ntawm guanine modulates translational txheej xwm.Inosine muaj antioxidant, anti-inflammatory thiab neuroprotective functionality.Inosine yog tshuaj raws li kev kho mob ntxiv rau cov hlab ntsha raug mob, o thiab oxidative kev nyuaj siab.Nws hloov cov txheej txheem lom neeg los ntawm adenosine receptors.Nws txhim kho neurite outgrowth nyob rau hauv kev nyuaj siab mob ntawm adenosine receptors.Inosine kuj tseem siv rau kev kho mob sepsis hauv kev kis kab mob.
3. Inosine yog cov khoom tseem ceeb ntawm tib neeg lub cev, ib hom tshuaj coenzyme dav siv hauv cov tshuaj thiab kev lag luam khoom noj.Nws tuaj yeem nkag mus rau cell membrane rau hauv lub cell ntawm lub cev ncaj qha, thiab ua rau lub cell nyob rau hauv lub xeev ntawm tsis muaj zog thiab anoxia txuas mus rau metabolize smoothly.Thiab nws tuaj yeem qhib caetone acid oxides, thiab koom nrog lub cev protein hauv synthesizing.
Kev siv tshuaj Inosine, xws li Inosine Tablets thiab Inosine Txhaj Tshuaj
1. Siv nyob rau hauv kev kho mob ntawm leukopenia thiab thrombocytopenia.
2. Nyob rau hauv kev kho mob ntawm tus kab mob siab thiab kab mob siab ntev thiab daim siab cirrhosis, hepatic encephalopathy.
3. Siv rau cov kab mob plawv atherosclerotic ( kab mob hauv lub plawv), myocardial infarction, rheumatic heart disease, cor pulmonale auxiliary drug use.
4. Siv los tiv thaiv thiab txo cov tshuaj tiv thaiv kab mob schistosomiasis los ntawm lub plawv thiab lub siab toxicity.
5. Siv rau cov kab mob qhov muag (central retinal o, optic atrophy) siv tshuaj pab.
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