Irbesartan Intermediate Side Chain Hydrochloride CAS 151257-01-1 Purity > 99.0% (HPLC) Hoobkas
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
CAS Nr .: 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Tshuaj npe | 2-Butyl-1,3-diazaspiro[4.4]Non-1-en-4-ib Hydrochloride |
Synonyms | Irbesartan Side Chain Hydrochloride;Irbesartan Lactam impurity;Irbesartan Impurity A;2-Butyl-4-spirocyclopentane-2-imidazolin-5-ib Hydrochloride;2-Butyl-1,3-diaza-spiro[4.4]Non-1-en-4-one HCl |
CAS Nr | 151257-01-1 |
CAT Number | RF-PI 1894 UAS |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C11H18N2O · HCl |
Molecular Luj | 230.74 Nws |
Solubility hauv dej | Soluble hauv dej |
Melting Point | 235.0 ~ 240.0 ℃ |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Yuav luag Dawb Dawb Crystalline Hmoov |
Purity / Analysis Method | > 99.0% (HPLC) |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.20% |
Tag nrho cov impurities | <1.00% |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Irbesartan (CAS: 138402-11-6) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one Hydrochloride (CAS: 151257-01-1), tseem hu ua Irbesartan Side Chain Hydrochloride, yog Intermediate ntawm Irbesartan (Avapro) (CAS) : 138402-11-6).Irbesartan yog angiotensin II receptor inhibitor, angiotensin II receptors muab faib ua AT1, AT2, irbesartan tuaj yeem cuam tshuam AngⅠ hloov mus rau AngII los ntawm kev xaiv thaiv cov AT1 receptor ntawm AngII, tshwj xeeb antagonize angiotensin converting enzyme 1 receptor (AT5 ntawm 0), AT1 antism ntawm 0. lub sij hawm tshaj li ntawm AT2, nws muaj peev xwm inhibit vasoconstriction thiab aldosterone tso tawm los ntawm kev xaiv thaiv kev khi AngII nrog AT1 receptor thiab ua rau cov nyhuv antihypertensive.Cov khoom no tsis inhibit angiotensin converting enzyme (ACE), renin, thiab lwm yam tshuaj hormones receptors, tsis txwv cov ntshav siab tswj thiab qhov sib npaug ntawm sodium ion channels.Irbesartan tseem tuaj yeem txo cov hluav taws xob hloov kho ntawm myocardium, yog li txo qis kev tuag ntawm cov neeg mob ntshav siab, nws yog cov tshuaj zoo tshaj plaws rau kev kho mob ntshav siab thiab kab mob plawv.