L-Histidine CAS 71-00-1 (H-His-OH) Kev Ntsuas 98.5 ~ 101.0% Lub Hoobkas Zoo
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm L-Histidine (H-His-OH; L-Nws; Abbreviated Nws lossis H) (CAS: 71-00-1) nrog cov khoom zoo.Raws li ib tug ntawm cov loj tshaj plaws amino acids lwm tus neeg nyob rau hauv Tuam Tshoj, Ruifu Chemical manufactures tsim nyog amino acids thiab derivatives mus rau thoob ntiaj teb cov qauv, xws li AJI, USP, EP, JP thiab FCC tus qauv.Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, me me thiab ntau ntau.Yog tias koj txaus siab rau L-Histidine,Please contact: alvin@ruifuchem.com
| Tshuaj npe | L-Histidine |
| Synonyms | H-Nws-OH;L-Nws;Abbreviated Nws los H;L-Histidine, Dawb Base;Laevo-Histidine;L-(+)-Histidin;Histidine;(S)-Histidine;(S)-4-(2-Amino-2-Carboxyethyl) imidazole;(S)-α-Amino-1H-Imidazole-4-Propanoic Acid;(2S)-2-Amino-3-(1H-Imidazol-4-yl)propanoic Acid;3-(1H-Imidazol-4-yl)-L-Alanine |
| Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 100 Tons ib Hlis |
| CAS Nr | 71-00-1 ib |
| Molecular Formula | C6H9N3O2 |
| Molecular Luj | 155.16 Nws |
| Melting Point | 281 ℃ (dej.) (lit.) |
| Solubility | Soluble hauv Dilute Hydrochloric Acid |
| Solubility hauv 1mol / L HCl | Yuav luag Transparency |
| Cia Temp. | Muab ntim rau hauv Qhuav, Khaws ntawm Chav Kub |
| COA & MSDS | Muaj |
| Kev faib tawm | Amino Acid Derivatives |
| Hom | Ruifu Tshuaj |
| Hazard Codes | Xn | RTECS | MS3070000 |
| Risk Statements | 22-36/37/38 ib | F | 10-23 |
| Cov lus hais txog kev nyab xeeb | 24/25-36/37-26-22 ib | TSCA | Yog lawm |
| WGK Germany | 2 | HS Code | 2933290090 ib |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb Crystals los yog Crystalline hmoov, me ntsis iab saj | Ua raws |
| Kev txheeb xyuas | Infrared Absorption Spectrum yog tsim | Ua raws |
| Kev sib hloov tshwj xeeb [α]20/D | 12.0 ° txog + 12.8 ° C (C = 11, 6 mol / L HCl) | + 12.3 ° C |
| State of Solution (Kev xa tawm) | Ntshiab thiab tsis muaj xim ≥98.0% | 98.5% |
| Chloride (Cl) | ≤ 0.020% | <0.020% |
| Sulfate (SO4) | ≤ 0.020% | <0.020% |
| Ammonium (NH4) | ≤ 0.020% | <0.020% |
| Hlau (Fe) | ≤10ppm | <10ppm |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤ 1.0ppm | <1.0ppm |
| Lwm yam Amino Acids | Ua raws | Ua raws |
| Poob rau ziab | ≤ 0.20% | 0.10% |
| Residue ntawm Ignition (Sulfated) | ≤0.10% | 0.08% |
| Assay | 98.5 mus rau 101.0% (Titration on qhuav Basis) | 99.7% |
| pH Test | 7.0 txog 8.5 (1.0g hauv 50 ml ntawm H2O) | 7.5 |
| Keeb kwm | Tsis yog Tsiaj Source | Ua raws |
| Xaus | Ua raws li tus qauv ntawm AJI97;USP 40 | |
| Txee lub neej | Txee Lub neej 24 Lub Hlis txij hnub tsim khoom yog tias khaws cia kom raug | |
| Kev siv tseem ceeb | Khoom noj khoom haus additives;Pharmaceuticals;Khoom noj khoom haus ntxiv | |
L-Histidine (H-His-OH) (CAS: 71-00-1) AJI97 Test Method
Kev txheeb xyuas: Sib piv cov infrared absorption spectrum ntawm cov qauv nrog cov qauv ntawm cov txheej txheem potassium bromide disc.
Kev sib hloov tshwj xeeb [α]20 / D: Cov Qauv Qhuav, C = 11, 6MOL / L HCl
State of Solution (Transmittance): .5g hauv 10ml ntawm H2O, yaj los ntawm cua sov spectrophotometer, 430nm, 10nm cell thickness.
Chloride (Cl): 0.7g, A-1, ref: 0.40ml ntawm 0.01mol / L HCl
Sulfate (SO4): 1.2g, (1), ref: 0.50ml ntawm 0.005mol / L H2SO4
Hlau (Fe): 1.5g, (1), ref: 1.5ml ntawm Hlau Std.(0.01 mg/ml)
Heavy Metals (Pb): 2.0g, (1), pH = 7, ref: 2.0ml ntawm Pb Std.(0.01 mg/ml)
Arsenic (As2O3): 2.0g, (1), ref: 2.0ml ntawm As2O3 Std.
Lwm Yam Amino Acids: Cov Qauv Xeem: 50μg, B-6-a, tswj: L-Nws 0.25μg
Poob rau ziab: ntawm 105 ℃ rau 3 teev.
Assay: Cov qauv qhuav, 150mg, (1), 2ml ntawm formic acid, 50ml ntawm glacial acetic acid, 0.1mol / L HCLO4 1ml = 15.516mg C6H9N3O2
pH Test: 1.0g hauv 50ml H2O)
L-Histidine (H-His-OH) (CAS: 71-00-1) USP36-NF31 Test Method
DEFINITION
Histidine muaj NLT 98.5% thiab NMT 101.5% ntawm L-Histidine (C6H9N3O2), suav ntawm lub hauv paus qhuav.
IDENTIFICATION
A. INFRARED ABSORPTION <197K> Cov Qauv thiab USP L-Histidine RS yog yav tas los recrystallized los ntawm 80% cawv.
QHIA
txheej txheem
Qauv: 150 mg ntawm Histidine
Tsis muaj: Sib tov 3 mL ntawm formic acid thiab 50 mL ntawm glacial acetic acid.
Titrimetric system
(Saib Titrimetry <541>)
Hom: Direct titration
Titrant: 0.1 N perchloric acid VS
Endpoint detection: Potentiometric
Kev Ntsuas: Dissolve cov qauv hauv 3 mL ntawm formic acid thiab 50mL ntawm glacial acetic acid.Titrate qeeb heev nrog Titrant.Ua qhov kev txiav txim siab Blank.
Xam cov feem pua ntawm Histidine (C 6H9N3O2) hauv cov qauv coj mus kuaj:
Result = {[(VS-VB) x N x F]/W} x100
VS = Titrant ntim tau noj los ntawm Cov Qauv (mL)
VB = Titrant ntim tau noj los ntawm Blank (mL)
N = qhov tseeb normality ntawm Titrant (mEq / mL)
F = equivalency factor, 155.2 mg/mEq
W = Sample nyhav (mg)
Kev lees txais: 98.5% ~ 101.5% ntawm lub hauv paus qhuav
IMPURITIES
RESIDUEON ON IGNITION <281>: NMT 0.4%
chloride thiab sulfate, chloride <221>
Standard tov: 0.50mL ntawm 0.020 N hydrochloric acid
Qauv: 0.73g ntawm Histidine
Kev lees txais: NMT 0.05%
chloride thiab sulfate, sulfate <221>
Standard tov: 0.10mL ntawm 0.020 N sulfuric acid
Qauv: 0.33g ntawm Histidine
Kev lees txais: NMT 0.03%
Hlau <241>: NMT 30ppm
Rho tawm cov hauv qab no:
HEAVY METALS, Method I <231>: NMT 15ppm
TXOJ CAI TSHIAB
Kev daws teeb meem tsim nyog: 0.4mg / mL txhua ntawm USP L-Histidine RS thiab USP L-Proline RS
Kev daws teeb meem: 0.05mg / mL ntawm USP L-Histidine RS hauv dej.[CEEB TOOM-Qhov kev daws teeb meem no muaj qhov sib npaug sib npaug rau 0.5% ntawm cov qauv tshuaj.]
Piv txwv li: 10mg / mL ntawm Histidine hauv dej
Chromatographic system (Saib Chromatography <621>, Thin-Layer Chromatography.)
Mode: TLC
Adsorbent: 0.25-mm txheej ntawm chromatographic silica gel sib tov
Daim ntawv ntim: 5μL
Tsim cov kuab tshuaj: Butyl cawv, glacial acetic acid, thiab dej (3: 1: 1)
Txau reagent: 2 mg / mL ntawm ninhydrin hauv kev sib xyaw ntawm butyl cawv thiab 2N acetic acid (95: 5)
Qhov system haum
Kev xav tau kev tsim nyog: Lub chromatogram ntawm qhov kev daws teeb meem tsim nyog nthuav tawm ob qhov sib cais kom meej.
Kev tsom xam
Cov Qauv: Cov kev daws teeb meem tsim nyog, Cov qauv kev daws teeb meem, thiab cov qauv kev daws teeb meem.
Tom qab cua qhuav lub phaj, tshuaj tsuag nrog tshuaj tsuag reagent, thiab cua sov ntawm 100 ° thiab 105 ° rau 15 min.Tshawb xyuas lub phaj hauv qab lub teeb dawb.
Kev lees txais cov qauv: Txhua qhov chaw thib ob ntawm cov qauv kev daws teeb meem tsis loj dua lossis hnyav dua li qhov chaw tseem ceeb ntawm Cov Txheej Txheem Kev daws teeb meem.
Tus kheej impurities: NMT 0.5%
Tag nrho impurities: NMT 2.0%
TSEEM CEEB
OPTICAL ROTATION, Kev sib hloov tshwj xeeb <781S>
Cov qauv tshuaj: 110 mg / mL hauv 6 N hydrochloric acid
Kev lees txais cov qauv: + 12.6 ° txog + 14.0 °
PH <791>
Sample kua: 20 mg/mL tov
Kev lees txais: 7.0 ~ 8.5
LOSSON RAU DRYING <731>: Qhuav ib qho qauv ntawm 105 ℃ rau 3 h: nws poob NMT 0.2% ntawm nws qhov hnyav.
TSEEM CEEB
PACKAGING THIAB STORAGE: Khaws rau hauv cov thawv kaw kom zoo.
USP REFERENCE STANDARDS <11>
USP L-Histidine RS
USP L-Proline RS UAS
Pob: Fluorinated Fwj, 25kg / hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias, qhuav thiab cua tshuab kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
L-Histidine (H-His-OH) (CAS: 71-00-1) Khoom Ua Haujlwm
1. L-Histidine yog ib qho tseem ceeb amino acid uas tsis tuaj yeem tsim los ntawm lwm cov as-ham, thiab yuav tsum muaj nyob rau hauv cov khoom noj kom muaj nyob rau hauv lub cev.
2. Feem ntau pom tau tias yog ib qho ua ntej rau cov tsos mob ua xua ua rau cov tshuaj histamine, ob qho tib si histidine thiab histamine muaj lub luag haujlwm tseem ceeb hauv lub cev dhau ntawm kev tsim txom cov neeg tsis haum tshuaj.
3. Histamine paub zoo txog nws lub luag haujlwm hauv stimulating inflammatory teb ntawm daim tawv nqaij thiab mucous daim nyias nyias xws li cov nyob rau hauv lub qhov ntswg - qhov kev txiav txim no yog ib qho tseem ceeb nyob rau hauv kev tiv thaiv ntawm cov teeb meem no thaum kis kab mob.
4. Histamine kuj txhawb kev tso tawm ntawm lub plab zom mov enzyme gastrin.Yog tias tsis muaj cov tshuaj histamine txaus, kev zom zaub mov zoo tuaj yeem ua rau tsis zoo.Yog tsis muaj cov khw muag khoom L-histidine txaus, lub cev tsis tuaj yeem tswj cov qib histamine txaus.
5. Tsis tshua paub zoo yog tias L-histidine yuav tsum tau los ntawm lub cev los tswj thiab siv cov khoom tseem ceeb xws li tooj liab, zinc, hlau, manganese thiab molybdenum.
L-Histidine (H-His-OH) (CAS: 71-00-1) Kev siv
1. Khoom noj khoom haus.Amino acid infusion thiab kev npaj cov amino acid yog cov khoom tseem ceeb heev.Kev kho mob, nws yog siv los kho gastric ulcer, anemia, allergy, thiab lwm yam. Nws yog siv rau kev tshawb fawb biochemical thiab tshuaj kho mob gastric ulcer, anemia, allergy, thiab lwm yam.
2. Amino acid tshuaj.Cov khoom tseem ceeb ntawm cov amino acid infusion thiab kev npaj cov amino acid yog siv los kho cov kab mob plawv xws li gastric ulcer, anemia, angina pectoris, arteritis thiab cardiac insufficiency.
3. Nws yog ib qho tseem ceeb ntawm cov amino acid infusion thiab compound amino acid npaj.Nws tuaj yeem siv los kho mob plab.Nws kuj tseem siv rau hauv kev tshawb fawb biochemical.
4. Siv los ua tshuaj raw khoom thiab khoom noj khoom haus additives.
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