L-(+)-Lysine Monohydrochloride CAS 657-27-2 (H-Lys-OH·HCl) Assay 98.5 ~ 101.0% Hoobkas High Quality
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm L-(+)-Lysine Monohydrochloride (H-Lys-OH·HCl) (CAS: 657-27-2) nrog cov khoom zoo, muaj peev xwm ntau lawm 1000 Tons ib. xyoo.Raws li ib tug ntawm cov loj tshaj plaws amino acids lwm tus neeg nyob rau hauv Tuam Tshoj, Ruifu Chemical muab cov amino acids mus rau thoob ntiaj teb cov qauv, xws li AJI, USP, EP, JP thiab FCC cov qauv.Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, me me thiab ntau ntau.Yog tias koj txaus siab rau L-(+)-Lysine Monohydrochloride,Please contact: alvin@ruifuchem.com
| Tshuaj npe | L-(+)-Lysine Monohydrochloride |
| Synonyms | H-Lys-OH · HCl;L-Lysine Monohydrochloride;L-Lysine Hydrochloride;L-Lysine HCl;Laevo-Lysine Hydrochloride;Lysine Hydrochloride;Lysine Monohydrochloride;(S)-2,6-Diaminohexanoic Acid Monohydrochloride |
| Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 1000 Tons ib xyoos |
| CAS Nr | 657-27-2 : kuv |
| Molecular Formula | C6H14N2O2 · HCl |
| Molecular Luj | 182.65 Nws |
| Melting Point | 263 ℃ (dec.) (lit.) |
| Qhov ntom | 1.28g / cm3 (20 ℃) |
| Dej Solubility | Soluble hauv dej, Yuav luag Transparency |
| Solubility | Dawb Soluble hauv dej thiab Formic Acid.Heev me ntsis Soluble nyob rau hauv Ethanol.Xyaum Insouble hauv Ether |
| Cia Temp. | Muab ntim rau hauv Qhuav, Khaws ntawm Chav Kub |
| COA & MSDS | Muaj |
| Kev faib tawm | Amino Acid thiab Derivatives |
| Hom | Ruifu Tshuaj |
| Risk Codes | 34 - Ua rau kub hnyiab |
| Kev nyab xeeb piav qhia | S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag. |
| UN IDs | UN 1789 8/PG 3 |
| WGK Germany | 2 |
| HS Code | 29 224 1900 IB |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb Crystals los yog Crystalline Hmoov | Ua raws |
| Kev txheeb xyuas | Infrared Absorption Spectrum yog tsim | Ua raws |
| Kev sib hloov tshwj xeeb [α]20/D | + 20.4 ° rau + 21.4 ° C = 8 hauv 6N HCl) | + 20.8 ° C |
| State of Solution (Kev xa tawm) | Ntshiab thiab tsis muaj xim ≥98.0% | 98.8% |
| Chloride (Cl) | 19.0 txog 19.6% | 19.15% |
| Sulfate (SO4) | ≤ 0.020% | <0.020% |
| Ammonium (NH4) | ≤ 0.020% | <0.020% |
| Hlau (Fe) | ≤10ppm | <10ppm |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤ 1.0ppm | <1.0ppm |
| Lwm yam Amino Acids | ≤0.50% (TLC) | Ua raws |
| Poob rau ziab | ≤0.40% (ntawm 105 ℃ rau 3 teev) | 0.25% |
| Residue ntawm Ignition (Sulfated) | ≤0.10% | 0.06% |
| Assay | 98.5 mus rau 101.5% (raws li Qhuav Basis) | 99.7% |
| Organic Volatile Impurities | Ua raws li qhov yuav tsum tau ua | Ua raws |
| pH Test | 5.0 txog 6.0 (1.0g hauv 10ml ntawm H2O) | 5.2 |
| Residual Solvents | Ua raws | Ua raws |
| Xaus | Ua tau raws li tus qauv ntawm AJI97;USP;JP | |
| Txee lub neej | 24 lub hlis txij hnub tsim khoom yog tias khaws cia kom raug | |
| Kev siv tseem ceeb | Amino Acids;Khoom noj khoom haus / Pub Additives;Tshuaj;Khoom noj khoom haus Enhancer;lwm. | |
L-(+)-Lysine Monohydrochloride (CAS: 657-27-2) AJI 97 Test Method
Kev txheeb xyuas: Sib piv cov infrared absorption spectrum ntawm cov qauv nrog cov qauv ntawm cov txheej txheem potassium bromide disc.
Kev sib hloov tshwj xeeb [α]20 / D: Cov Qauv Qhuav, C = 8, 6mol / L HCl
Lub xeev ntawm kev daws teeb meem (Transmittance): 1.0g hauv 10ml ntawm H2O spectrophotometer, 430nm, 10nm cell thickness.
Chloride (Cl): Cov Qauv Qhuav, 370mg, B-1
Ammonium (NH4): B-1
Sulfate (SO4): 1.2g, (1), ref: 0.50ml ntawm 0.005mol / L H2SO4
Hlau (Fe): 1.5g, (1), ref: 1.5ml ntawm Hlau Std.(0.01 mg/ml)
Heavy Metals (Pb): 2.0g, (4), ref: 2.0ml ntawm Pb Std.(0.01 mg/ml)
Arsenic (As2O3): 2.0g, (1), ref: 2.0ml ntawm As2O3 Std.
Lwm Yam Amino Acids: Test Sample: 50μg, S-6-a, tswj: L-Lys HCl 0.25μg
Poob rau ziab: ntawm 105 ℃ rau 3 teev.
Assay: Cov qauv qhuav, 110mg, (3), 2ml ntawm formic acid, 0.1mol/L HCLO4 1ml = 9.133mg C6H14N2O2 · HCl
pH Test: 1.0g hauv 10ml ntawm H2O
L-(+)-Lysine Monohydrochloride (CAS: 657-27-2) USP35 Test Method
DEFINITION
Lysine Hydrochloride muaj NLT 98.5% thiab NMT 101.5% ntawm L-Lysine Hydrochloride (C6H14N2O2·HCl), suav ntawm lub hauv paus qhuav.
IDENTIFICATION
A. INFRARED ABSORPTION <197K>
QHIA
txheej txheem
Qauv: 90 mg ntawm Lysine Hydrochloride
Tsis muaj: Sib tov 3 mL ntawm formic acid thiab 50 mL ntawm glacial acetic acid.
Titrimetric system
(Saib Titrimetry <541>)
Hom: Direct titration
Titrant: 0.1 N perchloric acid VS
Endpoint detection: Potentiometric
Kev Ntsuas: Dissolve cov qauv hauv 3 mL ntawm formic acid thiab 50mL ntawm glacial acetic acid.Ntxiv 10 mL ntawm mercuric acetate TS, thiab titrate nrog Titrant.Ua qhov kev txiav txim siab Blank.
Xam cov feem pua ntawm Lysine Hydrochloride (C6H14N2O2 · HCl) hauv cov qauv coj mus kuaj:
Result = {[(VS-VB) xNxF]/W} x100
VS = Titrant ntim tau noj los ntawm Cov Qauv (mL)
VB = Titrant ntim tau noj los ntawm Blank (mL)
N = qhov tseeb normality ntawm Titrant (mEq / mL)
F = equivalency factor, 91.33 mg/mEq
W = Sample nyhav (mg)
Kev lees txais: 98.5% ~ 101.5% ntawm lub hauv paus qhuav
Lwm yam khoom
Cov ntsiab lus ntawm chloride
Qauv: 350 mg ntawm Lysine Hydrochloride
Dej: 140 mL dej
Titrimetric system
(Saib Titrimetry <541>)
Hom: Direct titration
Tug: 0.1N nyiaj nitrate VS
Endpoint detection: Visual
Kev tsom xam: Hloov cov qauv mus rau lub plooj (porcelain casserole), thiab ntxiv 140 mL dej thiab 1 mL ntawm dichlorofluorescein TS.Titrate nrog Titrant kom txog rau thaum cov nyiaj chloride flocculates thiab cov sib tov tau txais cov xim liab liab.Ua qhov kev txiav txim siab Blank.
Xam qhov feem pua ntawm cov tshuaj chloride (Cl) hauv cov qauv coj mus kuaj:
Result = {[(VS − VB) × N × F]/W} × 100
VS = Titrant ntim tau noj los ntawm Sample (mL)
VB = Titrant ntim tau noj los ntawm Blank (mL)
N = qhov tseeb normality ntawm Titrant (mEq/mL)
F = equivalency factor, 35.45 mg/mEq
W = Sample nyhav (mg)
Kev lees txais: 19.0% ~ 19.6%
IMPURITIES
RESIDUE ON IGNITION <281>: NMT 0.1%
chloride thiab sulfate, sulfate <221>
Standard tov: 0.10mL ntawm 0.020 N sulfuric acid
Qauv: 0.33g ntawm Lysine Hydrochloride
Kev lees txais: NMT 0.03%
Hlau <241>: NMT 30ppm
Rho tawm cov hauv qab no:
HEAVY METALS, Method I <231>: NMT 15ppm
TXOJ CAI TSHIAB
Txuj kev daws: 0.05 mg / mL ntawm USP L-Lysine Hydrochloride RS hauv dej.[CEEB TOOM-Qhov kev daws teeb meem no muaj qhov sib npaug sib npaug rau 0.5% ntawm cov qauv tshuaj.]
Piv txwv li: 10mg / mL ntawm Lysine Hydrochloride hauv dej
Kev daws teeb meem tsim nyog: 0.4 mg / mL txhua ntawm USP L-Lysine Hydrochloride RS thiab USP Arginine Hydrochloride RS
Chromatographic system (Saib Chromatography <621>, Thin-Layer Chromatography.)
Mode: TLC
Adsorbent: 0.25-mm txheej ntawm chromatographic silica gel sib tov
Daim ntawv ntim: 5μL
Tsim cov kuab tshuaj: Isopropyl cawv thiab ammonium hydroxide (7: 3)
Txau reagent: 0.2 g ntawm ninhydrin hauv kev sib xyaw ntawm butyl cawv thiab 2N acetic acid (95: 5)
Qhov system haum
Kev xav tau kev tsim nyog: Lub chromatogram ntawm qhov kev daws teeb meem tsim nyog nthuav tawm ob qhov sib cais kom meej.
Kev tsom xam
Cov Qauv: Cov qauv kev daws teeb meem, Kev daws teeb meem tsim nyog, thiab cov qauv kev daws teeb meem.
Qhuav lub phaj ntawm 100 ° thiab 105 ° kom txog thaum ammonia ploj tag.Txau nrog Spray reagent, thiab kub ntawm 100 ° thiab 105 ° rau 15 min.Tshawb xyuas lub phaj hauv qab lub teeb dawb.
Kev lees txais cov qauv: Txhua qhov chaw thib ob ntawm cov qauv kev daws teeb meem tsis loj dua lossis hnyav dua li qhov chaw tseem ceeb ntawm Cov Txheej Txheem Kev daws teeb meem.
Tus kheej impurities: NMT 0.5%
Tag nrho impurities: NMT 2.0%
TSEEM CEEB
OPTICAL ROTATION, Kev sib hloov tshwj xeeb <781S>
Cov qauv tshuaj: 80 mg / mL hauv 6 N hydrochloric acid
Kev lees txais cov qauv: + 20.4 ° txog + 21.4 °
LOSSON DRYING <731>: Qhuav ib qho qauv ntawm 105 ℃ rau 3 h: nws poob NMT 0.4% ntawm nws qhov hnyav.
TSEEM CEEB
PACKAGING THIAB STORAGE: Khaws rau hauv cov thawv kaw kom zoo.
USP REFERENCE STANDARDS <11>
USP Arginine Hydrochloride RS
USP L-Lysine Hydrochloride RS
L-(+)-Lysine Monohydrochloride (CAS: 657-27-2) JP17 Test Method
L-Lysine Hydrochloride, thaum qhuav, muaj tsis pub tsawg tshaj 98.5% ntawm L-lysine hydrochloride (C6H14N2O2.HCl).
Kev piav qhia L-Lysine Hydrochloride tshwm sim ua cov hmoov dawb.Nws muaj me ntsis, yam ntxwv saj.
Nws yog dawb do soluble nyob rau hauv dej thiab formic acid, thiab xyaum insoluble nyob rau hauv ethanol (95).
Nws qhia tau hais tias siv lead ua polymorphism.
Kev txheeb xyuas (1) Txiav txim siab qhov infrared absorption spectrum ntawm L-Lysine Hydrochloride, yav tas los qhuav, raws li qhia nyob rau hauv cov poov tshuaj bromide disk txoj kev nyob rau hauv Infrared Spectrophotometry <2.25>, thiab sib piv cov spectrum nrog rau cov ntaub ntawv Spectrum: ob qho tib si spectra qhia zoo sib xws ntawm kev nqus ntawm tib yoj tus lej.Yog tias muaj qhov sib txawv ntawm qhov spectra, yaj L-Lysine Hydrochloride hauv dej, evaporate cov dej kom qhuav ntawm 60 ℃, thiab rov ua qhov kev sim nrog cov seem.
(2) Ib qho kev daws ntawm L-Lysine Hydrochloride (1 ntawm 10) teb rau Cov Kev Ntsuas Zoo <1.09> rau chloride.
Kev sib hloov kho qhov muag <2.49> [α]20 / D: +19.0 - +21.5 ° (tom qab ziab, 2 g, 6 mol / L hydrochloric acid TS, 25 mL, 100 mm)
pH <2.54> Dissolve 1.0 g ntawm L-Lysine Hydrochloride hauv 10 mL dej: pH ntawm cov tshuaj no yog nyob nruab nrab ntawm 5.0 thiab 6.0.
Purity (1) Clarity thiab xim ntawm kev daws - Dissolve 1.0 g ntawm L-Lysine Hydrochloride hauv 10 mL dej: cov tshuaj yog ntshiab thiab tsis muaj xim.
(2) Sulfate <1.14>- Ua qhov ntsuas nrog 0.6 g ntawm L-Lysine Hydrochloride.Npaj cov tshuaj tswj nrog 0.35 mL ntawm 0.005 mol / L sulfuric acid VS (tsis ntau tshaj 0.028%).
(3) Ammonium <1.02>-Ua qhov ntsuas nrog 0.25 g ntawm L-Lysine Hydrochloride.Npaj cov tshuaj tswj nrog 5.0 mL ntawm Standard Ammonium Solution (tsis ntau tshaj 0.02%).
(4) Cov hlau hnyav <1.07>-Tau nrog 2.0 g ntawm L-Lysine Hydrochloride raws li Txoj Kev 1, thiab ua qhov kev sim.Npaj cov tshuaj tswj nrog 2.0 mL ntawm Standard Lead Solution (tsis ntau tshaj 10 ppm).
(5) Arsenic <1.11>-Npaj cov tshuaj ntsuam xyuas nrog 1.0 g ntawm L-Lysine Hydrochloride raws li Txoj Kev 1, thiab ua qhov kev sim (tsis ntau tshaj 2 ppm).
(6) Lwm yam tshuaj-Dissolve 0.10 g ntawm L-Lysine Hydrochloride hauv 25 mL dej, thiab siv cov tshuaj no ua cov qauv tov.Pipet 1 mL ntawm cov qauv tov, ntxiv dej kom raws nraim 50 mL, pipet 5 mL ntawm cov tshuaj no, ntxiv dej kom raws nraim 20 mL, thiab siv cov tshuaj no raws li tus qauv tov.Ua qhov kev sim nrog cov kev daws teeb meem no raws li qhia hauv Thin-txheej Chromatography <2.03>.Spot 5μL txhua tus qauv kev daws teeb meem thiab cov qauv kev daws teeb meem ntawm lub phaj ntawm silica gel rau nyias txheej chromatography.Tsim lub phaj nrog sib tov ntawm 1-propanol thiab ammonia dej (28) (67:33) mus rau qhov deb li ntawm 10 cm, thiab qhuav lub phaj ntawm 100 ℃ rau 30 feeb.Txau cov phaj sib npaug nrog kev daws ntawm ninhydrin hauv acetone (1 hauv 50) thiab kub ntawm 80 ℃ rau 5 feeb: cov chaw uas tsis yog qhov chaw tseem ceeb ntawm cov qauv tshuaj tsis yog khaus ntau dua li qhov chaw los ntawm cov txheej txheem kev daws teeb meem.
Poob ntawm ziab <2.41> Tsis ntau tshaj 1.0% (1 g, 105 ℃, 3 teev).
Residue ntawm ignition <2.44> Tsis ntau tshaj 0.1% (1 g).
Assay Weigh kom meej txog 0.1 g ntawm L-Lysine Hydrochloride, yav tas los qhuav, yaj hauv 2 mL ntawm formic acid, ntxiv raws nraim 15 mL ntawm 0.1 mol / L perchloric acid VS, thiab kub rau hauv da dej rau 30 feeb.Tom qab txias, ntxiv 45 mL ntawm acetic acid (100), thiab titrate <2.50> qhov tshaj perchloric acid nrog 0.1 mol / L sodium acetate VS (potentiometric titration).Ua ib qho kev txiav txim siab dawb paug, thiab ua ib qho kev kho uas tsim nyog.
Txhua mL ntawm 0.1 mol / L perchloric acid VS ＝9.132 mg ntawm C6H14N2O2.HCl
Containers thiab cia Containers-Tight containers.
Pob: Fluorinated Fwj, 25kg / hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias, qhuav thiab cua tshuab kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.Khaws kom deb ntawm cov oxidizing muaj zog.
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
L-(+)-Lysine Monohydrochloride (H-Lys-OH·HCl) (CAS: 657-27-2) yog siv dav hauv cov khoom noj khoom haus thiab dej haus kev lag luam.Nws kuj tseem siv tau rau hauv cov tsiaj pub noj los ntawm L-Lysine.L-Lysine Monohydrochloride tuaj yeem siv rau hauv ntau yam kev lag luam xws li: khoom noj khoom haus, dej haus, tshuaj, kev ua liaj ua teb / tsiaj pub, thiab ntau yam kev lag luam.
Product Function & Applications:
1. Lysine HCL yog ib qho khoom noj khoom haus fortifier, uas muaj lub luag haujlwm ntawm kev ua kom qab los noj mov ntawm cov tsiaj nyeg thiab nqaij qaib, txhim kho cov kab mob tiv thaiv, txhawb kev kho qhov txhab, txhim kho cov nqaij zoo, txhim kho plab hnyuv, thiab ua kom cov paj hlwb, cov kab mob hlwb, cov protein thiab hemoglobin tseem ceeb. tshuaj.Feem ntau cov nyiaj ntxiv hauv qhov pub yog 0.1-0.2%.
2. Lysine HCL yog ib qho tseem ceeb amino acid nyob rau hauv tib neeg lub cev, uas tuaj yeem txhim kho hematopoietic muaj nuj nqi, txhim kho cov kua dej hauv plab, nce kev siv cov protein, ua kom cov kab mob tiv thaiv, tswj kev sib npaug ntawm metabolic, thiab pab txhawb kev loj hlob ntawm cov me nyuam cov tshuaj lom neeg lub cev thiab lub hlwb kev loj hlob.Tuam Tshoj qhia tias hmoov nplej, biscuits thiab qhob cij uas tuaj yeem siv rau kev ua cov noodles yog siv los ntawm 1 mus rau 2g / kg;0.3 mus rau 0.8g / kg hauv dej haus.
3. Lysine HCL yog ib qho ntawm cov amino acids tseem ceeb tshaj plaws, thiab kev lag luam amino acid tam sim no tau dhau los ua kev lag luam ntawm cov nplai thiab qhov tseem ceeb.Lysine feem ntau yog siv rau hauv cov khoom noj, tshuaj thiab pub.
Muaj nuj nqi:
1. Khoom noj khoom haus qib: khoom noj khoom haus ntxiv, siv rau seasoning nyob rau hauv mayonnaise, mis nyuj, instant noodles
2. Medcine qib: kev npaj rau kev sib xyaw amino acid hloov pauv, txhim kho kev ua haujlwm ntawm cov tshuaj
3. Pub qib: ua kom nqaij qaib sib npaug, txhim kho nqaij zoo thiab tsim khoom
L-(+)-Lysine Monohydrochloride yog tsim los ntawm fermentation siv hom kab mob corynebacteria, tshwj xeeb tshaj yog Corynebacterium glutamicum, uas muaj cov txheej txheem ntau yam xws li fermentation, cell sib cais los ntawm centrifugation lossis ultrafiltration, cov khoom sib cais thiab purification, evaporation thiab ziab.Vim tias L-Lysine tseem ceeb heev, kev siv zog tas li txhawm rau txhawm rau txhim kho cov txheej txheem fermentation, suav nrog kev mob thiab kev txhim kho cov txheej txheem nrog rau kev tshaj tawm xov xwm thiab kev ua haujlwm qis yog siv rau kev tsim L-lysine thiab lwm yam L-amino acids, kev ua haujlwm hauv kev sib xyaw tank lossis cua nqa fermenters.
