L-Serine CAS 56-45-1 (H-Ser-OH) Kev Ntsuas 98.5 ~ 101.0% Lub Hoobkas Zoo
Shanghai Ruifu Chemical Co., Ltd. yog tus xa khoom ntawm L-Serine (H-Ser-OH; Abbreviated Ser lossis S) (CAS: 56-45-1) nrog cov khoom zoo.Raws li ib tug ntawm cov loj tshaj plaws amino acids lwm tus neeg nyob rau hauv Tuam Tshoj, Ruifu Chemical muab cov amino acids raws li AJI, USP, EP, JP thiab FCC cov qauv.Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, me me thiab ntau ntau.Yog tias koj txaus siab rau L-Serine,Please contact: alvin@ruifuchem.com
| Tshuaj npe | L-Serine |
| Synonyms | H-Ser-OH;L-Ser;Sau ntawv Ser lossis S;(-)-Serine;Serine;Laevo-Serine;(S)-Serine;L-2-Amino-3-Hydroxypropionic Acid;(S)-2-Amino-3-Hydroxypropionic Acid;(S)-α-Amino-β-Hydroxypropionic Acid;L-3-Hydroxy-2-Aminopropionic Acid;3-Hydroxy-L-Alanine;β-Hydroxy-L-Alanine |
| Tshuag xwm txheej | Hauv Tshuag, Muaj Peev Xwm Ntau Lawm 500 Tons ib xyoos |
| CAS Nr | 56-45-1 ib |
| Molecular Formula | C3H7NO3 |
| Molecular Luj | 105.09 Nws |
| Melting Point | 222 ℃ (dej.) (lit.) |
| Qhov ntom | 1.6 |
| Dej Solubility | Soluble hauv dej, Yuav luag Transparency |
| Solubility | Dawb Soluble hauv Formic Acid.Xyaum Insoluble hauv Ethanol thiab hauv Ether.Dissolves hauv Dilute Hydrochloric Acid |
| Cia Temp. | Muab ntim rau hauv Qhuav, Khaws ntawm Chav Kub |
| COA & MSDS | Muaj |
| Kev faib tawm | Amino Acids thiab Derivatives |
| Hom | Ruifu Tshuaj |
| Cov khoom | Kev soj ntsuam Standards | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb Crystals los yog Crystalline Hmoov | Ua raws |
| Kev txheeb xyuas | Infrared Absorption Spectrum yog tsim | Ua raws |
| Kev sib hloov tshwj xeeb [α]20/D | 14.4 ° txog + 15.5 ° C = 10, 2N HCl | -33.8 ° |
| State of Solution (Kev xa tawm) | Ntshiab thiab tsis muaj xim ≥98.0% | 98.6% |
| Chloride (Cl) | ≤ 0.020% | <0.020% |
| Sulfate (SO4) | ≤ 0.020% | <0.020% |
| Ammonium (NH4) | ≤ 0.020% | <0.020% |
| Hlau (Fe) | ≤10ppm | <10ppm |
| Heavy Metals (Pb) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤ 1.0ppm | <1.0ppm |
| Lwm yam Amino Acids | Chromatographically Tsis Detectable | Ua raws |
| Poob rau ziab | ≤0.20% (ntawm 105 ℃, 3 teev) | 0.15% |
| Residue ntawm Ignition (Sulfated) | ≤0.10% | 0.06% |
| Assay | 98.5 txog 101.0% (Titration: Qhuav Basis) | 99.7% |
| pH Test | 5.2 txog 6.2 (1.0g hauv 10ml ntawm H2O) | 5.5 |
| Organic Volatile Impurities | Ua tau raws li qhov yuav tsum tau ua | Ua raws |
| Keeb kwm | Tsis yog Tsiaj Source | Ua raws |
| Residual Solvents | Ua raws | Ua raws |
| Xaus | Ua tau raws li AJI97, EP, USP, JP Test Specifications | |
| Txee lub neej | 24 lub hlis txij hnub tsim khoom yog tias khaws cia kom raug | |
| Kev siv tseem ceeb | Khoom noj khoom haus additives;Pharmaceuticals;Khoom noj khoom haus ntxiv;lwm. | |
Pob: Fluorinated Fwj, 25kg / hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias, qhuav thiab cua tshuab kom deb ntawm cov khoom tsis sib xws.Tiv thaiv los ntawm lub teeb thiab noo noo.
JP16
L-Serine, thaum qhuav, muaj tsis pub tsawg tshaj 98.5% thiab tsis ntau tshaj 101.0% ntawm C3H7NO3.
Nqe lus piav qhia L-Serine tshwm sim raws li cov muaju dawb los yog cov hmoov crystalline.Nws muaj me ntsis qab zib.Nws yog dawb do soluble nyob rau hauv dej thiab formic acid, thiab xyaum insoluble nyob rau hauv ethanol (99.5).Nws yaj hauv 2 mol / L hydrochloric acid TS.
Kev txheeb xyuas Kev txiav txim siab qhov infrared absorption spectrum ntawm L-Serine raws li qhia nyob rau hauv cov poov tshuaj bromide disk txoj kev nyob rau hauv Infrared Spectrophotometry <2.25>, thiab muab piv cov spectrum nrog cov Reference Spectrum: ob qho tib si spectra qhia zoo sib xws ntawm kev nqus ntawm tib lub nthwv dej.
Optical rotation <2.49> [a]20D: +14.0° ~ + 16.0° (Tom qab qhuav-ing, 2.5 g, 2 mol/L hydrochloric acid TS, 25 mL, 100 mm).
pH <2.54> Cov pH ntawm cov tshuaj npaj los ntawm dissolving 1.0 g ntawm L-Serine hauv 10 mL dej yog nyob nruab nrab ntawm 5.2 thiab 6.2.
Purity (1) Clarity thiab xim ntawm kev daws - Dissolve 1.0 g ntawm L-Serine hauv 10 mL dej: cov tshuaj yog ntshiab thiab tsis muaj xim.
(2) Chloride <1.03>- Ua qhov kev sim nrog 0.5 g ntawm L-Serine.Npaj cov tshuaj tswj nrog 0.30 mL ntawm 0.01mol / L hydrochloric acid VS (tsis ntau tshaj 0.021%)
(3) Sulfate <1.14> Ua qhov kev sim nrog 0.6 g ntawm L-Serine.Npaj cov tshuaj tswj nrog 0.35 mL ntawm 0.005mol / L sulfuric acid VS (tsis ntau tshaj 0.028%).
(4) Ammonium <1.02>-Ua qhov ntsuas nrog 0.25 g ntawm L-Serine.Npaj cov tshuaj tswj nrog 5.0 mL ntawm Standard Ammonium Solution (tsis ntau tshaj 0.02%).
(5) Cov Hlau Hnyav <1.07> Ua tiav nrog 2.0 g ntawm L-Serine raws li Txoj Kev 1, thiab ua qhov kev sim.Npaj cov tshuaj tswj nrog 2.0 mL ntawm Standard Lead Solution (tsis ntau tshaj 10 ppm).
(6) Hlau <1.10> Npaj cov tshuaj ntsuam xyuas nrog 1.0 g ntawm L-Serine raws li Txoj Kev 1, thiab ua qhov kev sim raws li Txoj Kev A. Npaj cov tshuaj tswj nrog 1.0mL ntawm Standard Iron Solution (tsis ntau tshaj 10 ppm) .
(7) Lwm yam tshuaj-Dissolve 0.10 g ntawm L-Serine nyob rau hauv 10mL dej, thiab siv cov tshuaj no raws li cov qauv tov.Pipet 1 mL ntawm cov qauv tov, ntxiv dej kom raws nraim 10 mL.Pipet 1 mL ntawm cov tshuaj no, ntxiv dej los ua kom tiav 50 mL, thiab siv cov tshuaj no raws li cov qauv kev daws teeb meem.Ua qhov kev sim nrog cov kev daws teeb meem no raws li qhia hauv Thin-txheej Chromatography <2.03>.Spot 5mLeachofthesamplessolution thiab cov qauv kev daws teeb meem ntawm ib lub phaj ntawm silica gel forthin-txheej chromatography.Tom qab ntawd txhim kho nrog kev sib xyaw ntawm 1-butanol, dej thiab acetic acid (100) (3: 1: 1) mus rau qhov deb li ntawm 10 cm, thiab qhuav lub phaj ntawm 809C rau 30 feeb.Txau ib qho kev daws teeb meem ntawm ninhydrinin sib tov ntawm methanol andacetic acid (100) (97: 3) (1 hauv 100) ntawm lub phaj, thiab cua sov ntawm 80 ℃ rau 10 feeb: qhov chaw uas tsis yog lub hauv paus ntsiab lus tau txais los ntawm cov qauv tshuaj tsis yog khaus ntau dua qhov chaw los ntawm cov txheej txheem daws teeb meem.
Poob rau ziab <2.41> Tsis ntau tshaj 0.3% (1 g, 105 ℃, 3 teev).
Residue ntawm Ignition <2.44> Tsis ntau tshaj 0.1% (1 g).
Kev ntsuas qhov hnyav yog kwv yees li 0.11 g ntawm L-Serine, yav tas los qhuav, yaj hauv 3 mL ntawm formic acid, ntxiv 50 mL ntawm acetic acid (100), thiab titrate <2.50> nrog 0.1 mol / L perchloric acid VS (potentiometric titration).Ua ib qho kev txiav txim siab dawb paug ib yam nkaus, thiab ua kom muaj kev kho qhov tsim nyog.
Txhua mL ntawm 0.1 mol / L perchloric acid VS＝10.51 mg ntawm C3H7NO3
Containers thiab cia Containers-Tight containers.
USP39-NF34
DEFINITION L-Serine muaj NLT 98.5% thiab NMT 101.5% ntawm L-serine (C3H7NO3), suav ntawm lub hauv paus qhuav.
IDENTIFICATION
A. INFRARED ABSORPTION <197K>
QHIA
txheej txheem
Qauv: 100mg ntawm Serine
Tsis muaj: Sib tov 3mL ntawm formic acid thiab 50mL ntawm glacial acetic acid.
Titrimetric system
(Saib Titrimetry <541>)
Hom: Direct titration
Titrant: 0.1 N perchloric acid VS
Endpoint detection: Potentiometric
Kev Ntsuam Xyuas: Dissolve cov qauv hauv 3mL ntawm formic acid thiab 50mL ntawm glacial acetic acid.Titrate nrog Titrant.
Ua qhov kev txiav txim siab Blank.
Xam qhov feem pua ntawm serine (C3H7NO3) hauv cov qauv coj mus kuaj:
Result = {[(VS-VB) xNxF]/W} x100
VS = Titrant ntim tau noj los ntawm Cov Qauv (mL)
VB = Titrant ntim tau noj los ntawm Blank (mL)
N = qhov tseeb normality ntawm Titrant (mEq / mL)
F = qhov sib npaug, 105.1mg / mEq
W = Sample nyhav (mg)
Kev lees txais: 98.5% ~ 101.5% ntawm lub hauv paus qhuav
IMPURITIES
RESIDUEON IGNITION <281>: NMT 0.1%
CHLORIDEAND SULFATE, Chloride <221>
Standard tov: 0.50mL ntawm 0.020 N hydrochloric acid
Qauv: 0.73g ntawm Serine
Kev lees txais: NMT 0.05%
Chlorideand Sulfate, Sulfate <221>
Standard tov: 0.10mL ntawm 0.020 N sulfuric acid
Qauv: 0.33g ntawm Serine
Kev lees txais: NMT 0.03%
Hlau <241>: NMT 30ppm
Rho tawm cov hauv qab no:
HEAVY METALS, Method I <231>: NMT 15ppm (Official 1-Jan-201)
TXOJ CAI TSHIAB
Kev daws teeb meem tsim nyog: 0.4mg / mL txhua ntawm USP L-Serine RS thiab USP L-Methionine RS hauv 0.1 N hydrochloric acid
Kev daws teeb meem: 0.05mg / mL ntawm USP L-Serine RS hauv 0.1 N hydrochloric acid.[CEEB TOOM-Qhov kev daws teeb meem no muaj qhov sib npaug sib npaug li 0.5% ntawm cov qauv tshuaj.]
Cov qauv tshuaj: 10mg / mL ntawm Serine hauv 0.1 N hydrochloric acid
Chromatographic system Saib Chromatography <621>, Thin-Layer Chromatography.)
Mode: TLC
Adsorbent: 0.25-mm txheej ntawm chromatographic silica gel sib tov
Daim ntawv ntim: 5μL
Tsim cov kuab tshuaj: Butyl cawv, glacial acebutyl cawv thiab 2N acetic acid (95: 5)
Qhov system haum
Kev xav tau kev tsim nyog: Lub chromatogram ntawm qhov kev daws teeb meem tsim nyog nthuav tawm ob qhov sib cais kom meej.
Kev tsom xam
Cov Qauv: Cov kev daws teeb meem tsim nyog, Cov qauv kev daws teeb meem, thiab cov qauv kev daws teeb meem.
Tom qab cua qhuav lub phaj, tshuaj tsuag nrog tshuaj tsuag reagent, thiab cua sov ntawm 100 ° thiab 105 ° rau 15 min.Tshawb xyuas lub phaj hauv qab lub teeb dawb.
Kev lees txais cov qauv: Txhua qhov chaw thib ob ntawm cov qauv kev daws teeb meem tsis loj dua lossis hnyav dua li qhov chaw tseem ceeb ntawm Cov Txheej Txheem Kev daws teeb meem.
Tus kheej impurities: NMT 0.5%
Tag nrho impurities: NMT 2.0%
TSEEM CEEB
OPTICAL ROTATION, Kev sib hloov tshwj xeeb <781S>
Cov qauv tshuaj: 100mg / mL hauv 2N hydrochloric acid
Kev lees txais cov qauv: + 14.0 ° txog + 15.6 °
LOSSON DRYING <731>: Qhuav ib qho qauv ntawm 105 ℃ rau 3 h: nws poob NMT 0.2% ntawm nws qhov hnyav.
TSEEM CEEB
KEV PAB CUAM: Khaws rau hauv cov thawv kaw kom zoo.
USP REFERENCE STANDARDS <11>
USP L-Methionine RS
USP L-Serine RS
Yuav Yuav Li Cas?Thov hu rauDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Xyoo Kev Paub?Peb muaj ntau tshaj li 15 xyoo ntawm kev paub nyob rau hauv kev tsim thiab export ntawm ib tug ntau yam ntawm zoo tshuaj intermediates los yog zoo tshuaj.
Kev lag luam loj?Muag rau kev lag luam hauv tsev, North America, Europe, India, Kauslim, Nyiv, Australia, thiab lwm yam.
Qhov zoo?Superior zoo, tus nqi pheej yig, kev pabcuam tshaj lij thiab kev txhawb nqa kev pabcuam, xa khoom sai.
ZooKev lees paub?Kev tswj xyuas nruj nruj.Cov cuab yeej tshaj lij rau kev txheeb xyuas suav nrog NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, thiab lwm yam.
Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
Factory Audit?Lub Hoobkas tshawb xyuas txais tos.Thov teem caij ua ntej.
MOQ?Tsis muaj MOQ.Kev txiav txim me me tau txais.
Lub sij hawm xa tuaj? Yog hais tias nyob rau hauv Tshuag, peb hnub shipping guaranteed.
Kev thauj mus los?Los ntawm Express (FedEx, DHL), los ntawm Cua, los ntawm hiav txwv.
Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
Kev cai Synthesis?tuaj yeem muab cov kev pabcuam sib xyaw ua ke kom haum rau koj cov kev xav tau tshawb fawb.
Cov nqe lus them nqi?Proforma invoice yuav raug xa ua ntej tom qab kev pom zoo ntawm kev txiav txim, kaw peb cov ntaub ntawv hauv tuam txhab nyiaj.Kev Them Nyiaj los ntawm T / T (Telex Transfer), PayPal, Western Union, thiab lwm yam.
| Hazard Cov Cim | Xis - Irritant |
| Risk Codes | 36/37/38 - Kab mob rau qhov muag, ua pa thiab tawv nqaij. |
| Kev nyab xeeb piav qhia | S24/25 - Tsis txhob sib cuag nrog daim tawv nqaij thiab qhov muag. S36 - Hnav khaub ncaws tiv thaiv zoo. S26 - Nyob rau hauv rooj plaub ntawm qhov muag, yaug tam sim ntawd nrog dej txaus thiab nrhiav kev kho mob. |
| WGK Germany | 3 |
| RTECS | VT8100000 |
| F | 3 |
| TSCA | Yog lawm |
| HS Code | 2922509099 ib |
L-Serine (H-Ser-OH; Abbreviated Ser lossis S) (CAS: 56-45-1) yog ib qho amino acid, nws yog ib qho ntawm cov proteinogenic amino acids.Nws cov codons hauv cov caj ces yog UCU, UCC, UCA, UCG, AGU thiab AGC.Los ntawm kev tsim txiaj ntawm pawg hydroxyl, serine yog cais raws li cov polar amino acid.
Muaj nuj nqi thiab daim ntawv thov ntawm L-Serine Cas 56-45-1
1. L-Serine yog siv los ua biochemical reagent thiab zaub mov additives;Siv hauv kev tshawb fawb biochemical, koom haum kab lis kev cai nruab nrab kev npaj, tshuaj siv rau cov amino acids ntawm cov tshuaj noj khoom haus.
2. L-Serine yog siv nyob rau hauv kev lag luam, L-Serine yog dav siv los kho lub thib peb tiam compound amino acid infusion thiab khoom noj khoom haus, thiab rau cov synthesis ntawm ntau yam ntawm txhob lo lo ntxhuav amino acid derivatives, xws li mob plawv, mob cancer, AIDS thiab caj ces. engineering ntawm cov tshuaj tshiab thiab lwm yam kev tiv thaiv amino acids.Khoom noj khoom haus thiab dej haus Field, L-Serine tuaj yeem siv los ua kis las dej haus, amino acids noj haus dej haus.Pub teb, L-Serine tuaj yeem siv rau tsiaj pub, txhawb tsiaj thiab kev loj hlob;
3. L-Serine yog siv los ua khoom noj khoom haus ntxiv, hauv cov tshuaj pleev ib ce ua cov khoom noj khoom haus ntawm daim tawv nqaij.
4. Muaj rau kev tshawb fawb biochemical thiab khoom noj khoom haus, tab sis kuj tuaj yeem siv los ua cov khoom siv hluavtaws serine raw khoom.
5. L-Serine muaj ntau hom kev siv tshuaj.Serine txhawb cov metabolism ntawm cov rog thiab fatty acids thiab pab tswj lub cev tiv thaiv kab mob.
6. L-Serine kuj tseem siv tau los ua cov khoom noj khoom haus ntxiv uas nws tuaj yeem pab txhim kho kev nco thiab hauv cov khoom siv tu tus kheej uas nws pab tsim cov tawv nqaij tshiab.
7. L-Serine tau siv rau hauv kev npaj ntawm Tris-BSAN tsis rau homogenization.Nws kuj tau siv rau kev soj ntsuam ntau ntawm kev tso tawm ntawm polypeptides hauv cov zis ib txwm.
8. L-Serine yog siv nyob rau hauv lub synthesis ntawm purines thiab pyrimidines raws li antibacterial/antifungal tus neeg sawv cev, raws li zoo raws li ua raws li ib tug proteinogenic compound.
9. L-Serine yog cais raws li cov amino acid tsis tseem ceeb.Nws yog siv los ua cov kab lis kev cai xov xwm ntawm tes thiab cov khoom siv raw rau kev lag luam biomanufacture ntawm kev kho cov proteins thiab monoclonal antibodies.
10. L-Serine los ntawm phosphorylation-hydroxy derivative tuaj yeem muab tau tom qab lub cev tseem ceeb ntawm P serine yog ib qho tseem ceeb ntawm phospholipids;
11. L-Serine nrog tus nqi pH ruaj khov ntawm lub luag haujlwm ntawm qhov muag te, qhov muag tee thiab tsis ua rau khaus;
12. L-Serine yog ib qho tseem ceeb ntawm lub ntuj moisturizing factor (NMF) yog ib qho ntawm stratum corneum los tuav lub luag haujlwm tseem ceeb ntawm cov dej, L-Serine yog tus yuam sij rau cov khoom siv tshuaj pleev ib ce zoo.
