L-Thyroxine CAS 51-48-9 Purity > 98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm L-Thyroxine (CAS: 51-48-9) nrog cov khoom zoo.Peb tuaj yeem muab COA, xa khoom thoob ntiaj teb, me me thiab ntau ntau.Yog tias koj txaus siab rau cov khoom no, thov xa cov ncauj lus kom ntxaws suav nrog CAS naj npawb, cov khoom npe, kom muaj nuj nqis rau peb.Please contact: alvin@ruifuchem.com
Tshuaj npe | L-Thyroxine |
Synonyms | Levothyroxine;L-T4;NSC 36397;(-) - Thyroxine;3,3',5,5'-Tetraiodo-L-Thyronine;3,5,3',5'-Tetraiodothyronine;beta-[(3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl] alanine;β-((3,5-Diiodo-4-Hydroxyphenoxy)-3,5-Diiodophenyl) alanine;o-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine |
CAS Nr | 51-48-9 : kuv |
CAT Number | TIAB SA 2891 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C15H11I4NO4 |
Molecular Luj | 776.87 ib |
Melting Point | 227.0 ~ 230.0 ℃ |
Boiling Point | 576.3 ± 50.0 ℃ |
Qhov ntom | 2.635 ib |
rhiab heev | Lub teeb Sensitive |
Dej Solubility | Insoluble hauv dej |
Solubility | Dissolve hauv 4M Ammonium Hydroxide hauv Methanol ntawm 50mg / ml |
Kev ruaj ntseg | ≥ 2 Xyoos |
HS Code | 29379000 ib |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
Purity / Analysis Method | > 98.0% (HPLC) |
Melting Point | 227.0 ~ 230.0 ℃ |
Kev sib hloov tshwj xeeb [α]20/D | -5.2° ~ -6.2° (C = 1, Ethanol: 1N NaOH = 2: 1) |
Heavy Metals (Pb) | ≤10ppm |
Poob rau ziab | <0.20% |
Residue ntawm Ignition | <0.10% |
Tag nrho cov impurities | <1.50% |
Infrared Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Pharmaceutical Intermediates |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
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Cov qauv?Cov khoom lag luam feem ntau muab cov qauv dawb rau kev soj ntsuam zoo, tus nqi thauj khoom yuav tsum tau them los ntawm cov neeg siv khoom.
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Cov ntaub ntawv?Kev pab cuam tom qab muag: COA, MOA, ROS, MSDS, thiab lwm yam tuaj yeem muab tau.
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L-Thyroxine (CAS: 51-48-9) los yog Levothyroxine yog cov thyroid hormones hluavtaws uas yog tshuaj zoo ib yam rau thyroxine (T4), uas yog ib txwm zais los ntawm cov hlwb follicular ntawm cov thyroid caj pas.Nws yog siv los kho cov thyroid hormone deficiency, thiab qee zaus los tiv thaiv kev rov tshwm sim ntawm cov thyroid cancer.Ib yam li nws tus kheej zais cia, Levothyroxine yog ib qho chiral compound hauv L-daim ntawv.Cov tshuaj muaj feem xyuam nrog dextrothyroxine (D-Thyroxine) tau siv yav dhau los ua kev kho mob rau hypercholesterolemia (nce qib roj cholesterol) tab sis raug tshem tawm vim muaj kev mob plawv.L-Thyroxine tsuas yog siv rau kev kho mob hypothyroidism, goiter, mob lymphocytic thyroiditis, myxedema coma, thiab stupor.Hauv vivo, L-Thyroxine (0.9 thiab 2.7 μg) inhibits synthesis thiab tso tawm ntawm thyrotropin induced los ntawm thyrotropin-tso cov tshuaj hormones los ntawm anterior pituitary hauv cov nas.Cov tshuaj uas muaj L-Thyroxine tau siv los kho hypothyroidism.Levothyroxine therapy yog siv nyob rau hauv cov ntaub ntawv ntawm deficiency ntawm cov thyroid hormones nyob rau hauv tib neeg lub cev, raws li nws tshwm sim nyob rau hauv lub deficiency ntawm thyroid, pituitary thiab hypothalamic qog (feem ntau, theem nrab thiab tertiary hypothyroidism).L-Thyroxine kuj tseem siv rau hauv kev kho mob ntawm euthyroid goiter thiab multinodular goiter, nrog rau cov thyroid nodules, subacute los yog chronic thyroiditis, los yog nyob rau hauv cov ntaub ntawv ntawm ib tug tom qab phais tsis txaus, los yog tom qab kev kho mob radiometabolic nyob rau hauv cov neeg mob uas muaj thyroid cancer.Cov teebmeem ntawm cov tshuaj no nyob ntawm ntau npaum li cas.Hauv cov koob tshuaj me me, L-Thyroxine nthuav tawm cov tshuaj anabolic.Hauv cov koob tshuaj nruab nrab, nws txhawb kev loj hlob thiab kev loj hlob ntawm cov ntaub so ntswg, metabolism ntawm cov protein, rog, thiab carbohydrates, nce kev ua haujlwm ntawm lub hauv paus paj hlwb thiab cov hlab plawv, nrog rau ob lub raum thiab lub siab.Hauv cov koob tshuaj loj, nws ua rau qeeb ntawm thyrotropic kev ua ntawm hypophysis thiab inhibits cov thyroid caj pas.