Lasofoxifene Tartrate CAS 190791-29-8 Chiral Purity ≥99.0% Purity ≥98.0% (HPLC) API Siab Purity
Chaw tsim tshuaj paus Supply nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Lasofoxifene Tartrate
CAS: 190791-29-8 Nr
Lasofoxifene Tartrate (CAS: 190791-29-8) hauv kev kho mob Postmenopausal Osteoporosis
Tshuaj npe | Lasofoxifene Tartrate |
Synonyms | (5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol Tartrate Oporia |
CAS Nr | 190791-29-8 |
CAT Number | RF-API 20 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
Molecular Formula | C28H31NO2.ClH |
Molecular Luj | 450.019 Nws |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder |
Moisture (KF) | ≤0.50% |
Hnyav Hlau | ≤ 20ppm |
Chiral Purity | ≥99.0% |
Purity / Analysis Method | ≥98.0% (HPLC) |
Poob rau ziab | ≤0.50% |
Residue ntawm Ignition | ≤0.50% |
Test Standard | Suav Pharmacopoeia (CP);Enterprise Standard |
Kev siv | Cov khoom xyaw tshuaj nquag (API);Postmenopausal Osteoporosis |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Shanghai Ruifu Chemical Co., Ltd. yog cov chaw tsim khoom thiab cov chaw muag khoom ntawm Lasofoxifene Tartrate (CAS: 190791-29-8) nrog cov khoom zoo.
Lasofoxifene Tartrate yog ib tiam thib peb, uas tsis yog-steroidal xaiv estrogen receptor modulator (SERM).Nws xaiv khi rau tib neeg ERalpha nrog IC50 tus nqi ntawm 1.5 nM thiab inhibits pob txha poob hauv ovariectomized nas.Hauv kev tshawb fawb soj ntsuam ntawm postmenopausal osteoporosis, 0.5 mg / hnub lasofoxifene tau cuam tshuam nrog txo qis kev pheej hmoo ntawm cov pob txha tsis muaj pob txha thiab pob txha, ER-zoo mob qog noj ntshav, kab mob plawv, thiab mob hlab ntsha tawg tab sis muaj kev pheej hmoo ntawm cov kab mob venous thromboembolic.Lasofoxifene kuj tau pom tias ua tus agonist inverse ntawm CB2 cannabinoid receptor, qhia tias nws muaj peev xwm yuav tsum tau repurposed raws li ib tug kho mob rau indications wherein CB2 yog lub hom phiaj.