Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0 ~ 102.0% Hoobkas

Lus piav qhia luv luv:

Lub npe tshuaj: Lenvatinib Mesylate

CAS: 857890-39-2 Nr

Kev Ntsuas: 98.0 ~ 102.0%

Cov tsos mob: Dawb rau Off-White Powder lossis Crystals

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Xa email rau peb

Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Nrog Siab Purity
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Tom ntej: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Tom ntej: Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Tom ntej: Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Chemical Properties:

Tshuaj npe	Lenvatinib Mesylate
Synonyms	4-[3-Chloro-4-[(cyclopropylaminocarbonyl)amino]phenoxy]-7-Methoxy-6-Quinolinecarboxamide Mesylate;E 7080 Mesylate;Lenvima
CAS Nr	857890-39-2
CAT Number	RF-PI 1975
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C21H19N4O4Cl.CH4O3S
Molecular Luj	522.96 ib
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Powder lossis Crystals
Kev txheeb xyuas	Los ntawm IR;Los ntawm UV;Los ntawm HPLC
Solubility	Me ntsis Soluble hauv dej, xyaum Insoluble hauv Ethanol
Melting Point	228.0 ~ 230.0 ℃
Cov ntsiab lus dej (KF)	<1.00%
Residue ntawm Ignition	<0.10%
Hnyav Hlau	<20 ppm
Yam khoom muaj feem
Ib qho Impurity	<0.50%
Tag nrho cov impurities	<1.00%
Assay / Analysis Method	98.0 ~ 102.0% (HPLC Raws li Kev Qhuav)
Kev ceev ceev	0.40g / ml ~ 0.60gm / ml
Test Standard	Enterprise Standard
Kev siv	API

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

Lenvatinib Mesylate (CAS: 857890-39-2) yog qhov ncauj thiab ntau lub hom phiaj inhibitor ntawm VEGFR1-3, FGFR1-4, PDGFR, KIT, thiab RET, nrog rau cov haujlwm muaj zog tiv thaiv kab mob.Lenvatinib Mesylate yog receptor tyrosine kinase (RTK) inhibitor uas muaj kev xaiv rau VEGFR2.Nws nthuav tawm cov haujlwm antineoplastic, thiab tau qhia txog kev kho mob ntawm cov neeg mob hauv zos rov qab los yog metastatic, kev loj hlob, radioactive iodine (RAI)-refractory sib txawv thyroid cancer.Lenvatinib Mesylate tau pom zoo thawj zaug los ntawm US Food and Drug Administration (FDA) thaum Lub Ob Hlis 13, 2015, tom qab ntawv pom zoo los ntawm Pharmaceuticals thiab Medical Devices Agency of Japan (PMDA) thaum Lub Peb Hlis 26, 2015, thiab pom zoo los ntawm European Medicine Agency (EMA) ntawm Lub Tsib Hlis 28, 2015. Nws tau tsim thiab ua lag luam raws li Lenvima® los ntawm Eisai.Lenvatinib Mesylate yog qhov ncauj ntau tus neeg txais tyrosine kinase inhibitor nrog ib qho tshwj xeeb khi hom uas xaiv inhibits kinase kev ua ub no ntawm vascular endothelial loj hlob zoo tshaj plaws (VEGF) receptors, ntxiv rau lwm yam proangiogenic thiab oncogenic pathway-txog tyrosine kinases xav tias yuav koom nrog cov qog proliferation. .Nws yog qhia rau kev kho mob ntawm cov kab mob radioiodine-refractory txawv cov thyroid cancer.Lenvimayog siv los ntawm nws tus kheej los kho cov qog nqaij hlav qog nqaij hlav sib txawv (DTC), ib hom qog nqaij hlav qog noj ntshav uas tsis tuaj yeem kho nrog cov xov tooj cua iodine thiab tab tom loj hlob.LENVIMA yog siv nrog rau lwm cov tshuaj hu ua everolimus los kho cov neeg laus uas muaj hom mob raum mob cancer hu ua advanced renal cell carcinoma (RCC) tom qab ib qho kev kho mob nrog lwm cov tshuaj tiv thaiv kab mob cancer.