Lenvatinib Mesylate Intermediate CAS 15568-85-1 Purity > 97.0% (HPLC) Hoobkas

Lus piav qhia luv luv:

5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione

CAS: 15568-85-1 Nr

Purity:> 97.0% (HPLC)

Cov tsos mob: Yellow Powder

Intermediate ntawm Lenvatinib Mesylate CAS 857890-39-2

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Nrog Siab Purity
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Tom ntej: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Tom ntej: Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Tom ntej: Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Chemical Properties:

Tshuaj npe	5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione
Synonyms	5-(Methoxymethylene) Meldrum's Acid;Cabozantinib impurity 56;Lenvatinib impurity 79
CAS Nr	15568-85-1
CAT Number	RF-PI 1967
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C8H10O5
Molecular Luj	186.16 Nws
Melting Point	132.0 ~ 134.0 ℃
Qhov ntom	1.297 ± 0.06 g / cm3
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Yellow hmoov
1 H NMR Spectrum	Raws li tus qauv
Purity / Analysis Method	> 97.0% (HPLC)
Tag nrho cov impurities	<3.00%
Test Standard	Enterprise Standard
Kev siv	Intermediate ntawm Lenvatinib Mesylate (CAS: 857890-39-2)

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo

Qhov zoo:

FAQ:

Daim ntawv thov:

5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS: 15568-85-1) yog ib qho nruab nrab ntawm Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib yog cov tshuaj kho mob qog noj ntshav uas tsim los ntawm Eisai Corporation ntawm Nyiv (Code: E7080), koom nrog cov inhibitor ntawm qhov ncauj ntau tus tyrosine kinase (RTK) thiab tuaj yeem cuam tshuam kinase kev ua ntawm vascular endothelial kev loj hlob yam (VEGF) Receptors VEGFR1 ( FLT1), VEGFR2 (KDR), thiab VEGFR3 (FLT4).Lenvatinib tseem tuaj yeem cuam tshuam kev koom tes ntawm lwm cov RTKs hauv pathological angiogenesis, qog loj hlob, thiab kev mob qog noj ntshav tshwj tsis yog rau lawv cov kev ua haujlwm ntawm tes xws li fibroblast kev loj hlob (FGF) receptors FGFR1, 2, 3, thiab 4;platelet-derived growth factor receptor (PDGFR [alpha]), KIT, thiab RET.[Cov Lus Qhia]: Lenvatinib yog qhov tsim nyog rau kev kho mob ntawm cov neeg mob qog nqaij hlav qog noj ntshav hauv zos lossis hom metastasis, hom kev nce qib thiab hom xov tooj cua iodine-refractory txawv.Thaum Lub Ob Hlis 13, 2015, US FDA tau pom zoo tshuaj tiv thaiv kab mob Lenvatinib rau kev kho mob qog noj ntshav.Lenvatinib yog ntau lub hom phiaj enzyme inhibitor, muaj peev xwm inhibiting VEGFR2 thiab VEGFR3 (vascular endothelial kev loj hlob receptor).Lub npe lag luam ntawm Lenvatinib yog Lenvima.Nyob rau lub Tsib Hlis 20, 2015, European Medicines Agency (EMA) tau pom zoo Lenvatinib rau kev kho mob ntawm invasive, hauv zos advanced lossis metastatic sib txawv (papillary, follicular, Hurthle type) thyroid cancer (DTC).Hauv kev sim, lub sij hawm ciaj sia nruab nrab rau cov neeg mob ntawm radioactive iodine-refractory DTC kho nrog Lenvatinib yog 18 lub hlis thaum tus nqi rau cov neeg mob uas siv cov placebo tsuas yog 3 lub hlis.