Letrozole CAS 112809-51-5 API Hoobkas Aromatase Inhibitor II Zoo
Muab khoom nrog High Purity thiab ruaj khov zoo
Lub npe tshuaj: Letrozole
CAS: 112809-51-5 Nr
Aromatase Inhibitor II
API High Quality, Commercial Production
| Tshuaj npe | Letrozole |
| Synonyms | CGS-20267;Femara |
| CAS Nr | 112809-51-5 |
| CAT Number | RF-API 86 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
| Molecular Formula | C17H11N5 |
| Molecular Luj | 285.3 ib |
| Melting Point | 181.0 txog 183.0 ℃ |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb rau Off-White Crystalline Hmoov |
| Solubility | Dawb Soluble nyob rau hauv Dichloromethane, me ntsis Soluble nyob rau hauv Ethanol thiab xyaum insoluble nyob rau hauv dej |
| Identification IR | Spectrum ntawm tus qauv sib raug raws li tus qauv siv |
| Kev txheeb xyuas HPLC | Lub sijhawm khaws cia ntawm cov qauv xeem sib raug raws li tus qauv siv |
| Cov ntsiab lus dej (los ntawm KF) | ≤ 0.30% |
| Residue ntawm Ignition | ≤0.10% |
| Yam khoom muaj feem | |
| Yam khoom muaj feem A | ≤ 0.30% |
| Yam khoom muaj feem B | ≤ 0.20% |
| Tej yam tsis meej tsis meej | ≤0.10% |
| Tag nrho Unspecified Impurities | ≤ 0.30% |
| Tag nrho cov impurities | ≤0.50% |
| Residual Solvents | |
| Ethyl Acetate | ≤0.50% |
| Methanol | ≤ 0.30% |
| Ethanol | ≤0.50% |
| DMF | ≤ 0.088% |
| Hnyav Hlau | ≤10ppm |
| Assay | 98.0% ~ 102.0% (raws li anhydrous hauv paus) |
| Txee lub neej | 24 Lub Hlis |
| Test Standard | Enterprise Standard |
| Kev siv | API, Aromatase Inhibitor II |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Letrozole (CAS 112809-51-5) yog ib feem ntawm ib tiam tshiab ntawm cov neeg nyiam aromatase inhibitors thiab yog ib qho khoom siv hluavtaws benzotriazole derivative.Letrozole inhibits aromatase kom txo qis cov tshuaj estrogen, yog li tiv thaiv cov tshuaj estrogen los ntawm stimulating qog loj hlob.Nws cov haujlwm hauv vivo yog 150-250 lub sijhawm muaj zog dua li ntawm thawj tiam aromatase inhibitor Amarante.Raws li nws muaj kev xaiv heev, nws yuav tsis cuam tshuam rau glucocorticoid, mineralocorticoid thiab cov thyroid ua haujlwm;Txawm tias muaj ntau npaum li cas, nws yuav tsis muaj qhov cuam tshuam rau adrenal corticosteroid secretion, muab nws qhov kev kho mob siab.Letrozole tsis muaj latent toxicity ntawm lub cev thiab lub hom phiaj ntawm lub cev, tsis muaj mutagenicity thiab carcinogenic cuam tshuam, muaj cov tshuaj lom neeg tsawg tsawg, muaj txiaj ntsig zoo, thiab muaj zog tiv thaiv kab mob ntau dua li lwm yam aromatase inhibitors thiab tshuaj antiestrogen.Letrozole yog qhov tsim nyog rau cov neeg mob qog nqaij hlav cancer mis tom qab lub cev tsis muaj zog uas tsis tau teb rau kev kho tshuaj estrogen thiab rau kev kho mob qog noj ntshav thaum ntxov.Nws yog siv los kho cov neeg mob postmenopausal nrog mob qog noj ntshav siab siab thiab ua haujlwm raws li kev kho mob thib ob kom ua raws li kev kho mob antiestrogen tsis ua tiav.
