Linagliptin CAS 668270-12-0 Purity ≥99.0% (HPLC) Hoobkas
Chaw tsim khoom, siab purity, coj mus muag ntau lawm
Lub npe tshuaj: Linagliptin
CAS: 668270-12-0 Nr
Tshuaj npe | Linagliptin |
Synonyms | IB-1356;8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H purine-2,6-dione |
CAS Nr | 668270-12-0 |
CAT Number | RF-API 105 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C25H28N8O2 |
Molecular Luj | 472.54 ib |
Melting Point | 197.0 txog 200.0 ℃ |
Solubility | Soluble hauv DMSO |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov |
NMR | Raws li tus qauv |
Purity / Analysis Method | ≥99.0% (HPLC) |
Poob rau ziab | ≤0.50% |
Residue ntawm Ignition | ≤0.10% |
Hnyav Hlau | ≤10ppm |
Yam khoom muaj feem | |
Ib leeg Impurity | ≤0.50% |
Tag nrho cov impurities | ≤ 1.0% |
Isomer | ≤ 0.15% |
Residual Solvents | |
Methanol | ≤3000ppm |
Isopropanol | ≤5000ppm |
DMF | ≤800ppm |
Dichloromethane | ≤600ppm |
Test Standard | Enterprise Standard |
Kev siv | API |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
Linagliptin (CAS: 668270-12-0) yog DPP-4 inhibitor tsim los ntawm Boehringer Ingelheim rau kev kho mob ntshav qab zib hom II.Ob tus yam ntxwv pharmacological uas teeb tsa linagliptin sib nrug los ntawm lwm yam DPP-4 inhibitors yog tias nws muaj cov tshuaj uas tsis yog-linear pharmacokinetic thiab tsis yog feem ntau tshem tawm los ntawm lub raum.Linagliptin (ib hnub ib zaug) tau pom zoo los ntawm US FDA ntawm 2 Tsib Hlis 2011 rau kev kho mob ntshav qab zib hom II.Nws tab tom ua lag luam los ntawm Boehringer Ingelheim thiab Lilly.Linagliptin, muag raws li lub npe Tradjenta ntawm lwm tus.Nws yog siv ua ke nrog kev tawm dag zog thiab kev noj haus.