Luliconazole CAS 187164-19-8 Purity ≥99.0% HPLC Hoobkas API Siab Zoo
Supply Luliconazole thiab Cov Khoom Sib Txuas
Luliconazole CAS 187164-19-8
1-Imidazolyl) acetonitrile CAS 98873-55-3
(S)-2,4-Dichloro-α-(Chloromethyl)benzyl cawv CAS 126534-31-4
| Tshuaj npe | Luliconazole |
| Synonyms | (2E)-2-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile;SIB 502 |
| CAS Nr | 187164-19-8 |
| CAT Number | RF-API 110 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C14H9Cl2N3S2 |
| Molecular Luj | 354.27 ib |
| Melting Point | 150.0 txog 154.0 ℃ |
| Kev sib hloov tshwj xeeb [a]20/D | -48.0 ° txog -53.0 ° C = 1, DMF |
| Solubility | Insoluble hauv dej;Soluble hauv Acetone;Methanol Soluble me ntsis |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Off-White to Light Yellow Crystalline Powder |
| Identification IR | Lub infrared spectrum ntawm tus qauv yuav tsum sib haum mus rau tus qauv siv |
| Kev txheeb xyuas HPLC | Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv kev daws teeb meem yuav tsum sib haum rau cov qauv kev daws teeb meem raws li tau txais hauv qhov kev sim |
| Poob rau ziab | ≤0.50% |
| Residue ntawm Ignition | ≤ 0.20% |
| Heavy Metals (Pb) | ≤ 20ppm |
| Yam khoom muaj feem | |
| Txhua tus neeg impurity | ≤ 0.20% |
| Tag nrho cov impurities | ≤0.50% |
| Residual Solvents | |
| Methanol | ≤3000ppm |
| Cov tshuaj acetonitrile | ≤410ppm |
| Dichloromethane | ≤600ppm |
| N-Hexane | ≤290ppm |
| Ethyl Acetate | ≤5000ppm |
| Tetrahydrofuran | ≤720ppm |
| Methyl tert-Butyl Ether | ≤5000ppm |
| N-Heptane | ≤5000ppm |
| Triethylamine | ≤320ppm |
| Dimethyl Sulfoxide | ≤5000ppm |
| Purity / Analysis Method | ≥99.0% (HPLC) (raws li lub hauv paus qhuav) |
| Test Standard | Enterprise Standard |
| Kev siv | Pharmaceutical Intermediates |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo.
Luliconazole (CAS: 187164-19-8) yog ib qho tshuaj tua kab mob imidazole tshuaj tua kab mob uas muaj dav-spectrum thiab muaj zog tiv thaiv kab mob.Luliconazole yog ib hom analogue ntawm lanoconazole.Nws tuaj yeem cuam tshuam nrog fungal cell phab ntsa synthesis thiab fungal loj hlob los ntawm kev txo qis ntawm ergosterol ntawm inhibiting lanosterol demethylase kev ua.Dhau li ntawm kev siv rau kev kho mob ntawm cov neeg ncaws pob ko taw, jock khaus thiab ringworm, nws kuj tau tsim kho rau onychomycosis (nail fungus) thiab tam sim no kuj tau nkag mus rau hauv kev kho mob theem III.Cov khoom no yog Ameslikas tsim los ntawm Japanese tshuaj tua kab Corporation (NihonNohyaku Co., Ltd.).Thaum Lub Kaum Ib Hlis 2013, FDA tau pom zoo 1% luliconazole qab zib rau kev nkag mus rau hauv kev ua lag luam rau kev kho mob ntawm cov neeg ncaws pob interdigital ko taw, jock khaus thiab ringworm nrog lub npe lag luam yog Luzu thiab thawj zaug nkag mus rau hauv kev lag luam hauv North America.Txij li thaum lub Plaub Hlis 2005, luliconazole tau pom zoo nkag mus rau hauv kev lag luam hauv Nyij Pooj raws li lub npe lag luam Lulicon.Thaum Lub Ib Hlis 2010 thiab Lub Rau Hli 2012, nws tau pom zoo rau kev lag luam hauv Is Nrias teb thiab Tuam Tshoj, feem.
