Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4 Purity > 98.0% (HPLC) Lenvatinib Mesylate Intermediate Factory
Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Nrog Siab Purity
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Tom ntej: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Tom ntej: Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Tom ntej: Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Tshuaj npe | Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate |
Synonyms | Lenvatinib impurity 47;4-Chloro-7-Methoxyquinoline-6-Carboxylic Acid Methyl Ester;4-Chloro-7-Methoxy-6-Quinolinecarboxylic Acid Methyl Ester;Lenvaint-D |
CAS Nr | 205448-66-4 |
CAT Number | RF-PI 1970 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C12H10ClNO3 |
Molecular Luj | 251.67 ib |
Boiling Point | 377.4 ± 37.0 ℃ |
Qhov ntom | 1.320 ± 0.06g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Off-White to Yellow Solid Powder |
1 H NMR Spectrum | Raws li tus qauv |
Purity / Analysis Method | > 98.0% (HPLC) |
Poob rau ziab | <1.00% |
Tag nrho cov impurities | <2.00% |
Test Standard | Enterprise Standard |
Kev siv | Intermediate / Impurity ntawm Lenvatinib Mesylate (CAS: 857890-39-2) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate (CAS: 205448-66-4) yog ib qho nruab nrab ntawm Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib yog cov tshuaj kho mob qog noj ntshav uas tsim los ntawm Eisai Corporation ntawm Nyiv (Code: E7080), koom nrog inhibitor ntawm qhov ncauj ntau tus neeg txais tyrosine kinase (RTK) thiab tuaj yeem cuam tshuam kinase kev ua ntawm vascular endothelial kev loj hlob yam Receptors R1 (FLT1), VEG-FR2 (KDR), R3 (FLT4).Lenvatinib tseem tuaj yeem cuam tshuam kev koom tes ntawm lwm cov RTKs hauv pathological angiogenesis, qog loj hlob, thiab kev mob qog noj ntshav tshwj tsis yog rau lawv cov kev ua haujlwm ntawm tes xws li fibroblast kev loj hlob (FGF) receptors FGFR1, 2, 3, thiab 4;platelet-derived growth factor receptor (PDGFR [alpha]), KIT, thiab RET.[Cov Lus Qhia]: Lenvatinib yog qhov tsim nyog rau kev kho mob ntawm cov neeg mob qog nqaij hlav qog noj ntshav hauv zos lossis hom metastasis, hom kev nce qib thiab hom xov tooj cua iodine-refractory txawv.