Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8 PF-07321332 Boceprevir Intermediate

Lus piav qhia luv luv:

Lub npe tshuaj: Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate

CAS: 328086-60-8 Nr

Cov tsos mob: Dawb rau Off-White hmoov

Intermediate ntawm PF-07321332 Paxlovid (CAS 2628280-40-8) thiab Boceprevir (CAS 394730-60-0)

High Quality, Commercial Production

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Product Detail

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Nqe lus piav qhia:

Kev Lag Luam Kev Lag Luam PF-07321332 Paxlovid Cov Khoom Siv Hluav Taws Xob nrog Cov Khoom Zoo
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(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
Tom ntej: 6,6-Dimethyl-3-azabicyclo [3.1.0]hexane CAS 943516-54-9

Chemical Properties:

Tshuaj npe	Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate
Synonyms	Methyl (S)-2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate;(αS,3S)-α-[(tert-Butyloxycarbonyl)aMino]-2-oxo-3-pyrrolidinepropanoic acid Methyl Ester;(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate
CAS Nr	328086-60-8
CAT Number	Qauv: RF-PI317
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms
Molecular Formula	C13H22N2O5
Molecular Luj	286.33 Nws
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb rau Off-White Powder
Kev Taw Qhia A	IR: Zoo ib yam li Cov Khoom Siv
Kev Qhia B	Lub Sijhawm Khaws Cia: Zoo ib yam li Cov Khoom Siv
Poob rau ziab	≤ 1.0%
Residue ntawm Ignition	≤ 0.20%
Ib leeg Impurity	≤0.50%
Tag nrho cov impurities	≤ 2.0%
Heavy Metals (Pb)	≤ 20ppm
Purity	≥98.0%
Test Standard	Enterprise Standard
Kev siv	Intermediate ntawm PF-07321332 Paxlovid (CAS 2628280-40-8) thiab Boceprevir (CAS 394730-60-0)

Pob & Cia:

Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.

Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.

Qhov zoo:

FAQ:

Daim ntawv thov:

Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate (CAS 328086-60-8) yog nruab nrab ntawm PF-07321332 Paxlovid (CAS 2628280-40) -8) thiab Boceprevir (CAS 394730-60-0).PF-07321332, lub ntsiab lus tseem ceeb ntawm Paxlovid (PF-07321332 thiab Ritonavir) uas yog tus kws tshawb nrhiav COVID-19 qhov ncauj tshuaj tiv thaiv tus neeg sib tw, yog qhov ncauj qhov ncauj bioavailable 3C-zoo li protease (3CLPRO) inhibitor nrog cov tshuaj tiv thaiv muaj zog tiv thaiv kab mob SARS-CoV-2. thiab COVID-19.Thaum Lub Kaum Ib Hlis 6th 2021, Pfizer tshaj tawm tias Paxlovid txo qis kev mus pw hauv tsev kho mob thiab kev tuag, raws li kev soj ntsuam ib ntus ntawm Theem 2/3 EPIC-HR (Kev Ntsuam Xyuas ntawm Protease Inhibition rau COVID-19 hauv Cov Neeg Mob Risk Siab) randomized, ob qhov muag tsis pom kev. ntawm cov neeg laus uas tsis nyob hauv tsev kho mob nrog COVID-19, uas muaj kev pheej hmoo siab ua rau mob hnyav.Boceprevir (EBP-520) yog HCV protease inhibitor (Ki = 14 nM) rau kev kho tus kab mob siab C.Boceprevir nrog pegylated interferon thiab ribavirin (PegIFN / RBV) tau ua kom muaj kev txhim kho hauv cov kab mob kis tau zoo ntawm cov neeg mob genotype 1 HCV.Boceprevir cuam tshuam nrog kev siv tshuaj tiv thaiv kab mob (IT) los ntawm inhibiting cytochrome P450 3A enzyme.