Molnupiravir N-1 CAS 2346620-55-9 COVID-19 Zoo
Kev Lag Luam Kev Lag Luam Molnupiravir thiab Cov Neeg Nruab Nrab cuam tshuam nrog Cov Khoom Zoo
Uridine CAS 58-96-8
Cytidine CAS 65-46-3
Molnupiravir N-1 CAS 2346620-55-9
Molnupiravir (EIDD-2801) CAS 2349386-89-4
| Tshuaj npe | Molnupiravir N-1 |
| Synonyms | ((3aR,4R,6R,6aR)-6-((E)-4-(hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3, 4-d][1,3]dioxol-4-yl)methyl isobutyrate;Molnupiravir Intermediate;Molnupiravir Dimethyl Dioxol impurity;Molnupiravir impurity 11 |
| CAS Nr | 2346620-55-9 |
| CAT Number | Qauv: RF-PI310 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale nce mus txog pua pua ntawm Kilograms |
| Molecular Formula | C16H23N3O7 |
| Molecular Luj | 369.37 ib |
| Solubility | Soluble hauv DMSO |
| Qhov ntom | 1.51 ± 0.1g / cm3 |
| Shipping kub | Ambient |
| Hom | Ruifu Tshuaj |
| Yam khoom | Specifications |
| Qhov tshwm sim | Dawb rau Off-White Powder |
| Poob rau ziab | ≤ 1.0% |
| Residue ntawm Ignition | ≤ 0.20% |
| Ib leeg Impurity | ≤0.50% |
| Tag nrho cov impurities | ≤ 2.0% |
| Hnyav Hlau | ≤ 20ppm |
| Purity | ≥98.0% |
| Test Standard | Enterprise Standard |
| Kev siv | Intermediate of Molnupiravir (CAS 2349386-89-4) COVID-19 |
Pob: Lub raj mis, Aluminium ntawv ci hnab, Cardboard nruas, 25kg / Nruas, los yog raws li tus neeg yuav tsum tau muaj.
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.
Molnupiravir N-1 (CAS 2346620-55-9), yog qhov nruab nrab ntawm Molnupiravir (CAS 2349386-89-4) hauv kev kho mob ntawm COVID-19.Molnupiravir (EIDD-2801) yog ib daim ntawv hais lus bioavailable ntawm lub zog muaj zog ribonucleoside analog uas cuam tshuam qhov kev rov ua dua ntawm ntau tus kab mob RNA suav nrog SARS-CoV-2, tus neeg sawv cev ntawm COVID-19.EIDD-2801 (7 mg / kg; po; ob zaug hauv ib hnub rau 3.5 hnub) txo qis cov kab mob hnyav thiab lub sijhawm ua npaws.Molnupiravir (EIDD-2801) yog hydrolyzed zoo hauv vivo tom qab nqus tau, ua rau pom tias tsuas yog dawb NHC hauv cov ntshav.EIDD-2801 robustly txo MERS-CoV infectious titers, viral RNA, thiab pathogenesis nyob rau hauv ob qho tib si prophylactic thiab thaum ntxov kho mob.Molnupiravir (EIDD-2801, MK-4482) yog ib qho kev hais lus bioavailable prodrug ntawm ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) nrog broad-spectrum antiviral kev ua haujlwm tawm tsam SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19.
