N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Coupling Reagent Purity > 99.0% (HPLC)

N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent rau kev npaj ntawm active esters ntawm amino acids.Peptide solid phase synthesis linking agent.
N-Hydroxysuccinimide feem ntau yog siv los pab carbodiimide-mediated peptide coupling los ntawm kev tsim cov ester active nruab nrab ntawm condensation ntawm lub nto carboxyl pawg thiab NHS.NHS-reactive ester intermediate yog qhov cuam tshuam rau nucleophilic nres los ntawm thawj amines thiab ua rau muaj kev ruaj ntseg amide bonds ntawm biomaterial nto thiab N-terminus ntawm peptide.
N-Hydroxysuccinimide yog hydroxylated succinimide uas tau siv dav hauv kev ua kom cov carboxylic acids rau NHS-esters los txhawb kev sib txuas nrog nucleophiles.Txoj hauv kev no feem ntau yog siv los ua kom cov kua qaub dawb ntawm fluorophores los txhawb kev sib txuas ntawm cov fluorophores rau amine residues ntawm cov protein.Kev siv NHS ester activation kuj tau piav qhia hauv kev sib txuas ntawm N-acyl amino acids.
Siv rau cov synthesis ntawm amino acid tiv thaiv, semi-synthetic kanamycin thiab tshuaj intermediates.N-hydroxybutyldiimide thiab nws derivatives yog ib qho tseem ceeb raw cov ntaub ntawv rau cov synthesis ntawm peptides, tshuaj tua kab mob, amino acids thiab proteins.N-hydroxybutyldiimide yog siv nyob rau hauv kev npaj ntawm active tshuaj. esters, thiab inhibition ntawm optically active nyhuv ntawm peptide coupling muaj ntau yam USES nyob rau hauv cov tshuaj, thiab kuj yog ib tug yooj yim tshuaj raw khoom.
N-Hydroxysuccinimide yog siv los txhim kho amidations hauv txoj kev carbodiimide.Nws kuj yog siv los qhib ib pawg carboxyl thiab reacts nrog amine los tsim amide.Nws koom nrog hauv kev npaj N-hydroxymaleimide-styrene copolymer.