Olmesartan Medoxomil CAS 144689-63-4 Purity > 99.5% (HPLC) API Hoobkas
Ruifu Chemical Supply Olmesartan Medoxomil Intermediates Nrog Cov Khoom Zoo:
Tom ntej: 4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
Tom ntej: 4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Tom ntej: Ethyl 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Tom ntej: Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Tom ntej: Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Tom ntej: Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Tshuaj npe | Olmesartan Medoxomil |
Synonyms | 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H- imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl) methyl Ester;SIB-866 |
CAS Nr | 144689-63-4 |
CAT Number | Qauv: RF-PI1730 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C29H30N6O6 |
Molecular Luj | 558.60 ib |
Melting Point | 180 ℃ (txog) |
Dej Solubility | Insoluble hauv dej;Me ntsis Soluble hauv DMSO |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Yuav luag Dawb Cyrstalline Hmoov |
Kev txheeb xyuas | IR, HPLC, UV: Yuav tsum ua raws li tus qauv siv |
Purity / Analysis Method | > 99.5% (HPLC ntawm Anhydrous thiab Solvent-Free Basis) |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.10% |
Yam khoom muaj feem | |
Olmesartan RRT 0.2 | <0.50% |
Olmesartan Medoxoil Related Compound A. RRT 0.7 | <0.20% |
Olefinic Impurity RRT 1.6 | <0.50% |
N-Alkyl Impurity RRT 3.4 | <0.10% |
Lwm yam impurity | <0.10% |
Tag nrho cov impurities | <0.50% |
Heavy Metals (raws li Pb) | <10ppm |
pH ntawm kev daws (2%, W / V) | 4.5 rau 6.5 |
Test Standard | Enterprise Standard;USP Txuj |
Kev siv | API |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) yog ib qho muaj zog thiab xaiv angiotensin II hom 1 (AT(1)) receptor antagonist nrog IC50 ntawm 66.2 μM., siv los kho cov ntshav siab.Siv raws li ib tug anti-hypertensive.Olmesartan ua haujlwm los ntawm kev thaiv kev khi ntawm angiotensin II rau AT1 receptors hauv cov leeg nqaij.Los ntawm kev thaiv cov kev sib txuas es tsis yog kev sib txuas ntawm angiotensin II, Olmesartan inhibits cov lus qhia tsis zoo ntawm renin secretion.Olmesartan Medoxomil yog ib qho tshuaj tiv thaiv uas yog de-esterified rau cov metabolite nquag, olmesartan.Olmesartan Medoxomil tau tsim tawm hauv Teb Chaws Asmeskas raws li Benicar, ib qho kev kho qhov ncauj rau ntshav siab.