Omeprazole CAS 73590-58-6 Assay > 99.5% API Hoobkas Zoo
Ruifu Chemical Supply Omeprazole Intermediates Nrog Siab Purity
Omeprazole CAS 73590-58-6
Omeprazole Hydroxy compound CAS 86604-78-6
Omeprazole Chloride Compound CAS 86604-75-3
Omeprazole sulfide CAS 73590-85-9
2-Mercapto-5-Methoxybenzimidazole CAS 37052-78-1
2-Cyano-3-Methylpyridine CAS 20970-75-6
2,3,5-Trimethylpyridine CAS 695-98-7
Tshuaj npe | Omeprazole |
Synonyms | 2-Chloromethyl-3,5-Dinmethyl-4-Methoxypyridine;5-Methoxy-2-[(4-Methoxy-3,5-Dimethyl-pyridin-2-yl)methylsulfinyl]-3H-Benzoimidazole |
CAS Nr | 73590-58-6 |
CAT Number | Qauv: RF-PI1913 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C17H19N3O3S |
Molecular Luj | 345.42 ib |
Melting Point | 151 ℃ (txog.) |
Qhov ntom | 1.332 g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb los yog Off-White Crystalline Hmoov, Tsis muaj ntxhiab tsw, |
Solubility | Yuav tsum soluble hauv dichloromethane, me ntsis soluble hauv methanol lossis ethanol, me ntsis soluble hauv acetone, insoluble hauv dej;Dissolve hauv 0.1mol / L NaOH kua. |
Kev txheeb xyuas (1) | Yuav tsum muaj cov tshuaj tiv thaiv zoo |
Kev txheeb xyuas (2) | Qhov siab tshaj plaws nqus tau tshwm sim ntawm 276nm thiab 305nm, thiab qhov nqus tsawg kawg tshwm sim ntawm 256nm thiab 281nm |
Kev txheeb xyuas (3) | Infrared absorption spectrum yuav tsum ua raws li tus qauv siv |
Clarity thiab Xim | Dichloromethane kua: Cov tshuaj yuav tsum yog ntshiab thiab tsis muaj xim;Yog tias tsis yog, qhov absorbance tsis ntau dua 0.1 ntawm 440nm |
Yam khoom muaj feem | Chromatographic Purity (HPLC) |
Ib leeg Impurity | <0.30% |
Tag nrho cov impurities | <1.00% |
Residual Solvents | |
n-Hexane | <0.024% |
Methanol | <0.009% |
Acetone | <0.15% |
Dichloromethane | <0.06% |
Poob rau ziab | <0.50% |
Residue ntawm Ignition | <0.10% |
Hnyav Hlau | <20 ppm |
Assay | > 99.5% ntawm C17H19N3O3S, xam rau cov khoom anhydrous |
Xaus | Kuaj raws li Suav Pharmacopoeia (2010 tsab), thiab cov txiaj ntsig tau raws li qhov yuav tsum tau ua |
Kev siv | API;Proton Pump Inhibitor (PPI) |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Omeprazole (CAS: 73590-58-6) tau qhia hauv xyoo 1980s.Omeprazole yog proton twj tso kua mis inhibitor siv los kho cov kab mob xws li gastroesophageal reflux disease (GERD), siv rau gastric thiab duodenal ulcers, reflux los yog erosive esophagitis, thiab Zollinger-Ellison syndrome.Nws kuj tseem siv tau rau cov kab mob plab thiab duodenal uas tsis muaj txiaj ntsig nrog H2 receptor antagonists.Kev txhaj tshuaj ntawm Omeprazole kuj tseem siv tau rau: 1 lub plab hnyuv los ntshav, xws li peptic thiab anastomic ulcer los ntshav, thiab kev tiv thaiv cov kab mob hnyav (xws li cerebral hemorrhage, mob hnyav, thiab lwm yam) thiab kev phais plab los ntawm txoj hnyuv los ntshav;2 mob plab hnyuv mucosal puas nyuaj los ntawm kev ntxhov siab lossis cov tshuaj uas tsis yog steroidal anti-inflammatory;3 cov tshuaj loog dav dav, tom qab phais, lossis cov neeg mob coma, los tiv thaiv cov kua qaub reflux thiab aspiration pneumonia;4 Ua ke nrog amoxicillin thiab clarithromycin, lossis nrog metronidazole thiab clarithromycin, nws tuaj yeem tua Helicobacter pylori (Hp).