Omeprazole sulfide CAS 73590-85-9 Purity > 99.0% (HPLC) Hoobkas
Ruifu Chemical Supply Omeprazole Intermediates Nrog Siab Purity
Omeprazole CAS 73590-58-6
Omeprazole Hydroxy compound CAS 86604-78-6
Omeprazole Chloride Compound CAS 86604-75-3
Omeprazole sulfide CAS 73590-85-9
2-Mercapto-5-Methoxybenzimidazole CAS 37052-78-1
2-Cyano-3-Methylpyridine CAS 20970-75-6
2,3,5-Trimethylpyridine CAS 695-98-7
Tshuaj npe | Omeprazole sulfide |
Synonyms | Ufiprazole;Omeprazole sulfur Ether;Esomeprazole EP impurity C;Omeprazole EP Impurity C;5-Methoxy-2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)methyl]thio]benzimidazole;5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)methyl]thio}-1H-Benzimidazole |
CAS Nr | 73590-85-9 |
CAT Number | RF-PI 1914 |
Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
Molecular Formula | C17H19N3O2S |
Molecular Luj | 329.42 ib |
Melting Point | 122.0 txog 126.0 ℃ |
Solubility | Soluble hauv Methanol |
Qhov ntom | 1.28 ± 0.10g / cm3 |
Hom | Ruifu Tshuaj |
Yam khoom | Specifications |
Qhov tshwm sim | Dawb rau Off-White Powder lossis Crystals |
Purity / Analysis Method | > 99.0% (HPLC) |
Poob rau ziab | <1.00% |
Residue ntawm Ignition | <0.20% |
Heavy Metals (raws li Pb) | <20 ppm |
Ib leeg Impurity | <0.50% |
Tag nrho cov impurities | <1.00% |
Infrared Spectrum | Raws li tus qauv |
Proton NMR Spectrum | Raws li tus qauv |
Test Standard | Enterprise Standard |
Kev siv | Intermediate ntawm Omeprazole / Esomeprazole |
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Omeprazole Sulfide (CAS: 73590-85-9) yog ib qho nruab nrab siv rau hauv kev tsim cov gastric proton twj tso kua mis inhibitors, Omeprazole (CAS: 73590-58-6) thiab Esomeprazole (CAS: 119141-88-7), Esomeprazole Sodium ( CAS: 161796-78-7 Nr.Raws li cov khoom lag luam degradation, nws tau tshaj tawm tias yog ib qho kev ua haujlwm ncaj qha ntawm cytochrome P450 2C19 hauv cov tib neeg lub siab microsomes (IC50 = 9.7 μM).Omeprazole sulfide yog ib qho metabolite ntawm Omeprazole.Esomeprazole Sodium yog sodium ntsev daim ntawv ntawm esomeprazole.Nws yog ib qho tshuaj tiv thaiv kab mob uas nquag siv, uas yog thawj zaug tau tsim los ntawm Swedish lub tuam txhab Astra Zeneca ua ntej.Nws belongs rau proton twj tso kua mis inhibitor.Lub twj tso kua mis proton inhibitor yog qhov kev xaiv tseem ceeb rau kev kho mob peptic ulcer, gastro-oesophageal reflux kab mob thiab lwm yam kab mob ntsig txog cov kua qaub.Tam sim no feem ntau siv tshuaj PPI suav nrog tsib yam: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole thiab Esomeprazole.Raws li thawj PPI, omeprazole cov tshuaj muaj txiaj ntsig zoo hauv kev kho cov kab mob kua qaub tau pom dav dav.Esomeprazole yog S-isomer ntawm Omeprazole, uas tuaj yeem txo qis gastric acid secretion los ntawm cov phiaj xwm tshwj xeeb.Nws yog qhov tshwj xeeb inhibitor rau proton twj tso kua mis inhibitor hauv parietal cell.Ua tsaug rau cov txiaj ntsig metabolic ntawm esomeprazole, nws muaj ntau dua bioavailability thiab ntau cov tshuaj pharmacokinetics zoo dua li nws tus khub, Omeprazole Sodium, nce cov tshuaj uas nce mus txog lub twj tso kua mis proton.Nws lub luag haujlwm ntawm kev tswj lub plab yog zoo dua li lwm cov twj tso kua mis proton inhibitors xws li Lansoprazole, Pantoprazole, thiab Rabeprazole.