Palonosetron Hydrochloride CAS 135729-62-3 Purity > 99.0% (HPLC) (T) API Hoobkas

Lus piav qhia luv luv:

Lub npe tshuaj: Palonosetron Hydrochloride

CAS: 135729-62-3 Nr

Cov tsos mob: Dawb los yog Off-White Crystalline Hmoov

Purity:> 99.0% (HPLC) (T)

Palonosetron Hydrochloride yog ib qho muaj zog heev, xaiv thiab hais lus nquag 5-HT3 receptor antagonist siv los tiv thaiv thiab kho cov tshuaj tua kab mob vim xeev siab thiab ntuav (CINV).Antiemetic.

Hu rau: Dr. Alvin Huang

Txawb/Wechat/WhatsApp: +86-15026746401

Inquiry: alvin@ruifuchem.com

Xa email rau peb

Product Detail

Yam khoom

Khoom cim npe

Nqe lus piav qhia:

Kev Lag Luam Kev Lag Luam Palonosetron Hydrochloride thiab Cov Khoom Siv Hluav Taws Xob:
(S)-1,2,3,4-Tetrahydro-1-Napthhoic Acid CAS: 85977-52-2
(R)-1,2,3,4-Tetrahedro-1-Napthhoic Acid CAS: 23357-47-3
(S)-3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Napthoic Acid CAS 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API

Chemical Properties:

Tshuaj npe	Palonosetron Hydrochloride
Synonyms	Palonosetron HCl;(S, S) - Palonosetron Hydrochloride;RS-25259;RS25259 197;(S)-2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-Hexahydro-1H-Benzo[de]isoquinolin-1-ib Hydrochloride;(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-Hexahydro-1H-benz[de]isoquinolin-1-ib Hydrochloride ;Aloxi;Onicit
CAS Nr	135729-62-3
CAT Number	RF-API 03
Tshuag xwm txheej	Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons
Molecular Formula	C19H24N2O · HCl
Molecular Luj	332.87 ib
Qhov xwm txheej kom zam	Thaum tshav kub kub Sensitive
Melting Point	307 ℃ (txog.)
Solubility hauv dej	Soluble tag nrho hauv dej
Solubility	Heev me ntsis Soluble nyob rau hauv Ethanol
Shipping kub	Ambient Kub
COA & MSDS	Muaj
Hom	Ruifu Tshuaj

Specifications:

Yam khoom	Specifications
Qhov tshwm sim	Dawb los yog Off-White Crystalline Hmoov
Palonosetron Hydrochloride	> 99.0% (HPLC) (T)
Kev sib hloov tshwj xeeb [α]20/D	-98.0° ~ 104.0°
Kev txheeb xyuas	Ntxiv BiI7K4, Tsim cov txiv kab ntxwv daj Precipitate
Kev txheeb xyuas	TLC Ua raws li Cov Khoom Siv Siv
Kev txheeb xyuas	IR Raws li tus qauv IR
Kev txheeb xyuas	Kev txheeb xyuas raws li chloride
Solubility	Dawb Soluble hauv dej, sparingly soluble hauv Methanol, me ntsis soluble hauv ethanol, insoluble hauv acetone
Clarity thiab xim ntawm kev daws	Max.Yellow No. 2 Standard Color Solution
pH Vaub	4.5 ~ 6.5 (10mg / ml)
Muaj feem xyuam
Related Compound A (NO)	<0.10%
Related Compound B (Ene-NO)	<0.10%
Related Compound C (S, R)	<0.10%
Related Compound D (R, S)	<0.50%
Palonosetron Enantiomer	<0.10%
Related Compound E (3-Ene)	<0.50%
Ib leeg tsis hais txog impurity	<0.10%
Residual Solvents
Ethanol	<3000ppm
Tetrahydrofuran	<5000ppm
DMF	<880ppm
Ib txwm Hexane	<290ppm
Methyl Cawv	<3000ppm
Isopropanol	<5000ppm
Methylbenzene	<890ppm
Dej	<0.30%
Residue ntawm Ignition	<0.20%
Poob rau ziab	<1.00%
Hnyav Hlau	<10ppm
Test Standard	Tebchaws Asmeskas Pharmacopoeia (USP);European Pharmacopoeia (EP)
Kev siv	Palonosetron Hydrochloride API;5-HT3 Antagonist;CINV

Pob & Cia:

Pob: Lub raj mis, Cardboard Nruas, 25kg / Nruas, lossis raws li cov neeg siv khoom xav tau.

Cia:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb, noo noo thiab kab tsuag.

Qhov zoo:

FAQ:

Daim ntawv thov:

Palonosetron Hydrochloride (CAS: 135729-62-3) yog ib qho tshuaj tiv thaiv xeev siab thiab ntuav, uas yog ib hom tshiab uas muaj kev xaiv zoo, siab affinity 5-HT3 receptor antagonist uas tuaj yeem thaiv qhov ntuav reflex chaw peripheral neurons presynaptic 5-HT.Receptor excitement ncaj qha cuam tshuam rau hauv nruab nrab paj hlwb hauv 5-HT.Impulse receptor excitement generated los ntawm lub luag hauj lwm ntawm vagal afferent hlab ntsha tom qab cheeb tsam, thaiv cov hlab ntsha vagus xaus nyob rau hauv lub plab, tiv thaiv cov teeb meem rau 5-HT.Receptor trigger zone tuaj yeem txo qhov tshwm sim ntawm xeev siab thiab ntuav.Central chaw kho mob rau kev kho mob hnyav emetogenic chemotherapy induced qeeb xeev siab thiab ntuav.Vim nws cov nyhuv curative siab, me ntsis phiv, ntev ib nrab-lub neej (txog 40 h), me me npaum li cas, thiab hais txog, nws tau nyiam ntau xim.

Nrog 1,2,3,4-Tetrahydro-1-Naphthoic Acid ua cov khoom pib, qhov sib cais, amination, txo, cyclization, ntsev ntawm palonosetron hydrochloride granisetron.Cov kev tshawb fawb soj ntsuam tau pom tias palonosetron tuaj yeem siv tau zoo nrog corticosteroids, tshuaj tua kab mob, tshuaj tua kab mob, tshuaj antispasmodics thiab anticholinergic tshuaj raws li cov khoom pib, kev sib cais, amination, txo, cyclization, ntsev ntawm palonosetron hydrochloride granisetron.