Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Kev Ntsuam Xyuas 97.5 ~ 102.0% Hoobkas
Ruifu Chemical Supply Nrog High Purity
Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
N-Methyl Paroxetine CAS 110429-36-2
| Tshuaj npe | Paroxetine Hydrochloride Hemihydrate |
| Synonyms | (3S,4R)-(-)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Hydrochloride Hemihydrate;Paxil;Seroxat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl |
| CAS Nr | 110429-35-1 |
| CAT Number | RF-PI 1946 |
| Tshuag xwm txheej | Nyob rau hauv Tshuag, ntau lawm Scale mus txog Tons |
| Molecular Formula | C19H20FNO3 · HCl · 1/2H2O |
| Molecular Luj | 374.84 ib |
| Melting Point | 140.0 ~ 143.0 ℃ |
| Kev sib hloov tshwj xeeb [α]20/D | -88.0° to -92.0° (C=1, MeOH, Calcd.on anh.substance) |
| Solubility | Xyaum Insoluble hauv dej;Soluble heev hauv Dimethylformamide, Methanol;Soluble hauv Ethanol |
| Hom | Ruifu Tshuaj |
| Cov ntsiab lus | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog Yuav luag Dawb Crystalline Hmoov | Ua raws |
| Kev Taw Qhia A | Infrared absorption spectrum yuav tsum ua raws li cov ntaub ntawv siv spectrum | Ua raws |
| Kev Qhia B | Lub ntsiab ncov cheeb tsam thiab lub sijhawm khaws cia ntawm cov tshuaj ntsuam xyuas yuav tsum ua raws li cov lus qhia siv | Ua raws |
| Kev txheeb xyuas C | Dej (KF) | Ua raws |
| Kev Taw Qhia D | Cov tshuaj chlorides | Ua raws |
| Impurity D | ≤ 0.20% | Tsis muaj |
| impurity G | ≤ 0.001% | |
| Yam khoom muaj feem | impurity A: ≤0.30% | 0.03% |
| Unspecified impurities: Rau txhua impurity, ≤0.10% | 0.06% | |
| Tag nrho cov impurities: ≤0.50% | 0.10% | |
| Hnyav Hlau | ≤ 0.002% | <0.002% |
| Dej (KF) | 2.20% ~ 2.70%. | 2.46% |
| Sulfated tshauv | ≤0.10% | <0.10% |
| Assay | 97.5% ~ 102.0% (Anhydrous Tshuaj) | 100.2% |
| Residual Solvents | ||
| Methanol | ≤ 0.30% | 0.001% |
| Acetone | ≤0.50% | 0.001% |
| Isopropanol | ≤0.50% | 0.04% |
| Dichloromethane | ≤0.06% | Tsis muaj |
| Toluene | ≤ 0.089% | 0.003% |
| Xaus: Ua raws li EP7.0. | ||
Pob: Lub raj mis, Aluminium ntawv ci hnab, 25kg / Cardboard Nruas, los yog raws li tus neeg yuav tsum tau muaj
Cia txias:Khaws rau hauv cov thawv ntim khoom ntawm qhov chaw txias thiab qhuav;Tiv thaiv los ntawm lub teeb thiab noo noo
Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) yog ib qho ntawm cov muaj zog tshaj plaws thiab xaiv cov tshuaj serotonin reuptake inhibitors (SSRI);antidepressant.Nws yog phenylpiperidine derivative, yog ib qho muaj zog thiab xaiv ST (serotonin transporter / 5-HT) uptake inhibitor.Nws ua los ntawm kev khi rau ST (serotonin transporter / SERT) nrog siab affinity (Ki = 05 nM).Antidepressant thiab anxiolytic hauv vivo.Paroxetine hydrochloride tuaj yeem siv los kho kev nyuaj siab, uas yog cov tshuaj tiv thaiv kev nyuaj siab tshiab.Nws kuj tseem tuaj yeem siv los kho kev ntxhov siab, kev ntxhov siab dav dav, kev ntxhov siab hauv zej zog, kev tsis sib haum xeeb (OCD), insomnia, premenstrual syndrome, ejaculation ntxov ntxov thiab lwm yam kab mob, nrog kev kho kom zoo thiab tsis zoo tshwm sim.Kho txhua yam kev nyuaj siab.Nrog rau kev nyuaj siab nrog kev ntxhov siab thiab kev nyuaj siab reactive.Cov tsos mob ntawm kev nyuaj siab: qaug zog, pw tsaug zog tsis zoo, tsis muaj kev txaus siab thiab txaus siab rau kev ua ub no txhua hnub, tsis qab los noj mov.Tom qab cov nyhuv curative txaus siab, nws tuaj yeem tiv thaiv qhov rov tshwm sim ntawm kev nyuaj siab.
